mechlorethamine has been researched along with Disease Exacerbation in 21 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proportion of intravenous drug abusers (IVDA) in HIV-HD (38%) is higher than in French HIV-infected population as a whole (20." | 3.78 | Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors. ( Andrieu, JM; Brice, P; Colonna, P; Gastaut, JA; Lévy, R; Raphaël, M; Taillan, B; Tourani, JM, 1995) |
| "This supports, that parapsoriasis is not a distinct entity, but an early stage of MF." | 1.39 | Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis. ( Fenger-Gron, M; Iversen, L; Lindahl, LM, 2013) |
| "The treatment results of our Hodgkin's disease patients improved, additionally we showed that patients with early stage favourable disease the treatment toxicity should be reduced, while patients with advanced, unfavourable prognosis (10% of all patients) aggressive primary treatment should be used even with more severe side effects and complications." | 1.34 | [Our experiences in treating patients with Hodgkin disease in the last decade]. ( Gergely, L; Illés, A; Keresztes, K; Miltényi, Z; Ress, Z; Simon, Z; Vadász, G; Váróczy, L, 2007) |
| "Clinical features predictive of disease progression include initial lymphadenopathy (stage IIA) and lack of complete response to initial treatment." | 1.30 | Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides. ( Chow, S; Hoppe, RT; Kim, YH; Varghese, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tewari-Singh, N | 2 |
| Jain, AK | 2 |
| Inturi, S | 1 |
| White, CW | 2 |
| Agarwal, R | 2 |
| Orlicky, DJ | 1 |
| Malaviya, R | 1 |
| Sunil, VR | 1 |
| Venosa, A | 1 |
| Verissimo, VL | 1 |
| Cervelli, JA | 1 |
| Vayas, KN | 1 |
| Hall, L | 1 |
| Laskin, JD | 1 |
| Laskin, DL | 1 |
| Lindahl, LM | 1 |
| Fenger-Gron, M | 1 |
| Iversen, L | 1 |
| Bonadonna, G | 1 |
| Viviani, S | 1 |
| Bonfante, V | 1 |
| Gianni, AM | 1 |
| Valagussa, P | 1 |
| Simon, Z | 1 |
| Keresztes, K | 1 |
| Miltényi, Z | 1 |
| Ress, Z | 1 |
| Váróczy, L | 1 |
| Vadász, G | 1 |
| Gergely, L | 1 |
| Illés, A | 1 |
| Advani, R | 1 |
| Maeda, L | 1 |
| Lavori, P | 1 |
| Quon, A | 1 |
| Hoppe, R | 1 |
| Breslin, S | 1 |
| Rosenberg, SA | 1 |
| Horning, SJ | 1 |
| Lévy, R | 1 |
| Colonna, P | 1 |
| Tourani, JM | 1 |
| Gastaut, JA | 1 |
| Brice, P | 2 |
| Raphaël, M | 1 |
| Taillan, B | 1 |
| Andrieu, JM | 1 |
| Haim, N | 1 |
| Leviov, M | 1 |
| Ben-Arieh, Y | 1 |
| Epelbaum, R | 1 |
| Freidin, N | 1 |
| Reshef, R | 1 |
| Ben-Shahar, M | 1 |
| Wirth, A | 1 |
| Corry, J | 1 |
| Laidlaw, C | 1 |
| Matthews, J | 1 |
| Liew, KH | 1 |
| Crowley, JJ | 1 |
| Nikko, A | 1 |
| Varghese, A | 2 |
| Hoppe, RT | 2 |
| Kim, YH | 2 |
| Vonderheid, EC | 1 |
| Ekbote, SK | 1 |
| Kerrigan, K | 1 |
| Kalmanson, JD | 1 |
| Van Scott, EJ | 1 |
| Rook, AH | 1 |
| Abrams, JT | 1 |
| Delfau-Larue, MH | 1 |
| Dalac, S | 1 |
| Lepage, E | 2 |
| Petrella, T | 1 |
| Wechsler, J | 1 |
| Farcet, JP | 1 |
| Bagot, M | 1 |
| Chow, S | 1 |
| Lemoli, RM | 1 |
| Visani, G | 1 |
| Leopardi, G | 1 |
| Motta, MR | 1 |
| Rizzi, S | 1 |
| Testoni, N | 1 |
| Curti, A | 1 |
| Tura, S | 1 |
| Yang, JM | 1 |
| Yang, GY | 1 |
| Medina, DJ | 1 |
| Vassil, AD | 1 |
| Liao, J | 1 |
| Hait, WN | 1 |
| Meddeb, B | 1 |
| Ben Lakhal, R | 1 |
| Bel Hadj Ali, Z | 1 |
| Ben Abid, H | 1 |
| Hafsia, R | 1 |
| Hafsia, A | 1 |
| Fisher, RI | 1 |
| Dana, BW | 1 |
| LeBlanc, M | 1 |
| Kjeldsberg, C | 1 |
| Forman, JD | 1 |
| Unger, JM | 1 |
| Balcerzak, SP | 1 |
| Gaynor, ER | 1 |
| Roy, V | 1 |
| Miller, T | 1 |
| Duvic, M | 1 |
| Colin, P | 1 |
| Berger, F | 1 |
| de Kerviler, E | 1 |
| Diviné, M | 1 |
| Bouaffia, F | 1 |
| Kerneis, Y | 1 |
| Blanc, M | 1 |
| Fermé, C | 1 |
| Carde, P | 1 |
| Cavalli, F | 1 |
| Diehl, V | 1 |
| Franklin, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimization of the Primary Therapy for Patients With Hodgkin's Lymphoma and Evaluation of the Positron Emission Tomography (PET) as a Diagnostic Tool for Primary Staging and Assessment of the Effects of the Therapy[NCT00188149] | Phase 4 | 300 participants | Interventional | 2000-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mechlorethamine and Disease Exacerbation
| Article | Year |
|---|---|
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
Current treatment of Cutaneous T-Cell Lymphoma.
Topics: Administration, Oral; Administration, Topical; Anticarcinogenic Agents; Apoptosis; Bexarotene; Biops | 2001 |
Is escalated BEACOPP a standard therapy for advanced Hodgkin's disease?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials, Phase III | 2000 |
5 trials available for mechlorethamine and Disease Exacerbation
| Article | Year |
|---|---|
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
Intermediate and high-grade gastric non-Hodgkin's lymphoma: a prospective study of non-surgical treatment with primary chemotherapy, with or without radiotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression; | 1995 |
[Results of a prospective protocol for the treatment of adult Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; D | 1999 |
Interferon alpha consolidation after intensive chemotherapy does not prolong the progression-free survival of patients with low-grade non-Hodgkin's lymphoma: results of the Southwest Oncology Group randomized phase III study 8809.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression; | 2000 |
Advanced Hodgkin disease with large mediastinal involvement can be treated with eight cycles of chemotherapy alone after a major response to six cycles of chemotherapy: a study of 82 patients from the Groupes d'Etudes des Lymphomes de l'Adulte H89 trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; Doxorubicin; | 2001 |
14 other studies available for mechlorethamine and Disease Exacerbation
| Article | Year |
|---|---|
Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.
Topics: Animals; Biomarkers; Disease Progression; Edema; Erythema; Irritants; Mechlorethamine; Mice; Mice, H | 2013 |
Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.
Topics: Animals; Blister; Chemical Warfare Agents; Dermis; Disease Progression; Epidermis; Hyperkeratosis, E | 2014 |
Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody.
Topics: Alkylating Agents; Animals; Antibodies, Monoclonal; Biomarkers; Chemical Warfare Agents; Disease Pro | 2015 |
Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Disease Progression; Female; Humans; Male; | 2013 |
Survival in Hodgkin's disease patients--report of 25 years of experience at the Milan Cancer Institute.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Dacarbazine; Disea | 2005 |
[Our experiences in treating patients with Hodgkin disease in the last decade].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Ad | 2007 |
Impact of positive positron emission tomography on prediction of freedom from progression after Stanford V chemotherapy in Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; Doxorubicin; | 2007 |
Salvage radiotherapy for Hodgkin's disease following chemotherapy failure.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Dacarbazine; Di | 1997 |
Mycosis fungoides in young patients: clinical characteristics and outcome.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Case-Control Studies; Cause of De | 1998 |
The prognostic significance of delayed hypersensitivity to dinitrochlorobenzene and mechlorethamine hydrochloride in cutaneous T cell lymphoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Dinitrochlorobenzene; Disease P | 1998 |
Prognostic significance of a polymerase chain reaction-detectable dominant T-lymphocyte clone in cutaneous lesions of patients with mycosis fungoides.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antineoplastic A | 1998 |
Clinical characteristics and long-term outcome of patients with generalized patch and/or plaque (T2) mycosis fungoides.
Topics: Adult; Aged; Aged, 80 and over; Cause of Death; Disease Progression; Female; Humans; Lymph Nodes; Ly | 1999 |
Autologous transplantation of chemotherapy-purged PBSC collections from high-risk leukemia patients: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow Purging; Busulfan; Combined Mod | 1999 |
Treatment of multidrug resistant (MDR1) murine leukemia with P-glycoprotein substrates accelerates the course of the disease.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cell Movement; Dise | 1999 |