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mechlorethamine and Delayed Hypersensitivity

mechlorethamine has been researched along with Delayed Hypersensitivity in 18 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"Seventy-six patients with mycosis fungoides (MF) were given topical mechlorethamine hydrochloride therapy."7.67Response of mycosis fungoides to topical chemotherapy with mechlorethamine. ( Dubin, N; Parnes, RE; Ramsay, DL, 1984)
"One hundred seventeen patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride."7.67Topical mechlorethamine therapy for early stage mycosis fungoides. ( Halperin, PS; Ramsay, DL; Zeleniuch-Jacquotte, A, 1988)
"Seventy-six patients with mycosis fungoides (MF) were given topical mechlorethamine hydrochloride therapy."3.67Response of mycosis fungoides to topical chemotherapy with mechlorethamine. ( Dubin, N; Parnes, RE; Ramsay, DL, 1984)
"One hundred seventeen patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride."3.67Topical mechlorethamine therapy for early stage mycosis fungoides. ( Halperin, PS; Ramsay, DL; Zeleniuch-Jacquotte, A, 1988)
"A group of 220 patients with mycosis fungoides (MF) and other lymphomatous diseases was treated with sustained topical applications of dilute aqueous solutions of mechlorethamine hydrochloride for intervals ranging in excess of seven years."3.65Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results. ( Asbell, SO; Grekin, DA; Johnson, WC; Van Scott, EJ; Vonderheid, EC, 1977)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's2 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BOREL, Y1
SCHWARTZ, R1
SIPOS, K1
ALLEN, IV1
Waldorf, DS1
Haynes, HA1
Van Scott, EJ6
Nusbaum, BP1
Edwards, EK1
Horwitz, SN1
Frost, P1
Ramsay, DL2
Parnes, RE1
Dubin, N1
Smith, KJ1
Vidmar, D1
Skelton, HG1
Hackley, BE1
Vonderheid, EC2
Ekbote, SK1
Kerrigan, K1
Kalmanson, JD2
Rook, AH1
Abrams, JT1
Johnson, WC1
Grekin, DA1
Asbell, SO1
Maurice, PA1
Lederrey, C1
Halperin, PS1
Zeleniuch-Jacquotte, A1
Yu, RJ1
Maguire, HC1
Baer, RL1
Michaelides, P1
Prestia, AE1
Winters, PL1
Devita, VT1
Serpick, AA1
Carbone, PP1
Schwab, JH1

Trials

1 trial available for mechlorethamine and Delayed Hypersensitivity

ArticleYear
Psoriasis therapy. The effect of UV radiation on sensitization to mechlorethamine.
    Archives of dermatology, 1983, Volume: 119, Issue:2

    Topics: Administration, Topical; Aged; Clinical Trials as Topic; Dermatitis, Contact; Drug Hypersensitivity;

1983

Other Studies

17 other studies available for mechlorethamine and Delayed Hypersensitivity

ArticleYear
INHIBITION OF IMMEDIATE AND DELAYED HYPERSENSITIVITY IN THE RABBIT BY 6-MERCAPTOPURINE.
    Journal of immunology (Baltimore, Md. : 1950), 1964, Volume: 92

    Topics: gamma-Globulins; Hypersensitivity; Hypersensitivity, Delayed; Immunity; Mechlorethamine; Mercaptopur

1964
PAINTING TREATMENT OF NITROGEN MUSTARD IN MYCOSIS FUNGOIDES.
    Dermatologica, 1965, Volume: 130

    Topics: Drug Therapy; Erythema; Fever; Geriatrics; Humans; Hypersensitivity; Hypersensitivity, Delayed; Hype

1965
THE EFFECT OF GRANULOCYTOPENIA ON EXPERIMENTAL TUBERCULIN FEVER.
    Immunology, 1965, Volume: 8

    Topics: Agranulocytosis; Fever; Hypersensitivity; Hypersensitivity, Delayed; Leukopenia; Lipopolysaccharides

1965
Cutaneous hypersensitivity and desensitization to mechlorethamine in patients with mycosis fungoides lymphoma.
    Annals of internal medicine, 1967, Volume: 67, Issue:2

    Topics: Cyclophosphamide; Dermatitis, Contact; Desensitization, Immunologic; Dosage Forms; Drug Hypersensiti

1967
Response of mycosis fungoides to topical chemotherapy with mechlorethamine.
    Archives of dermatology, 1984, Volume: 120, Issue:12

    Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Drug Hypersensitivity; Female; Humans; Hype

1984
Improved results of delayed-type hypersensitivity skin testing in HIV-infected patients treated with topical dinitrochlorobenzene.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:3 Pt 1

    Topics: Catechols; CD8-Positive T-Lymphocytes; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene

1996
The prognostic significance of delayed hypersensitivity to dinitrochlorobenzene and mechlorethamine hydrochloride in cutaneous T cell lymphoma.
    The Journal of investigative dermatology, 1998, Volume: 110, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Dinitrochlorobenzene; Disease P

1998
Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results.
    Archives of dermatology, 1977, Volume: 113, Issue:4

    Topics: Administration, Topical; Aged; Desensitization, Immunologic; Dinitrochlorobenzene; Drug Hypersensiti

1977
Increased sensitivity of chronic lymphocytic leukemia lymphocytes to alkylating agents due to a deficient DNA repair mechanism.
    European journal of cancer, 1977, Volume: 13, Issue:9

    Topics: DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Hypersensitivity, Delayed; Leuk

1977
Topical mechlorethamine therapy for early stage mycosis fungoides.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:4

    Topics: Administration, Topical; Adult; Aged; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delay

1988
Complete remissions of mycosis fungoides lymphoma induced by topical nitrogen mustard (HN2). Control of delayed hypersensitivity to HN2 by desensitization and by induction of specific immunologic tolerance.
    Cancer, 1973, Volume: 32, Issue:1

    Topics: Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Immune Tolerance; Immunologic Tech

1973
Antimitotic, antigenic, and structural relationships of nitrogen mustard and its homologues.
    The Journal of investigative dermatology, 1974, Volume: 62, Issue:4

    Topics: Animals; Antigens; Cross Reactions; Drug Hypersensitivity; Epithelial Cells; Epithelium; Ethanolamin

1974
Induction of delayed hypersensitivity to nitrogen mustard in the guinea-pig.
    The British journal of dermatology, 1974, Volume: 91, Issue:1

    Topics: Allergens; Animals; Biopsy; Dimethyl Sulfoxide; Disease Models, Animal; Erythema; Female; Freund's A

1974
Failure to induce immune tolerance to nitrogen mustard. Intravenous administration preceding topical use in patients with proriasis.
    The Journal of investigative dermatology, 1972, Volume: 58, Issue:1

    Topics: Adult; Aged; Humans; Hypersensitivity, Delayed; Immune Tolerance; Immunosuppression Therapy; Male; M

1972
Responses of mycosis fungoides to intensive external treatment with nitrogen mustard.
    Archives of dermatology, 1970, Volume: 102, Issue:5

    Topics: Adult; Aged; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Leukocyte Count; Male

1970
Combination chemotherapy in the treatment of advanced Hodgkin's disease.
    Annals of internal medicine, 1970, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Drug Synerg

1970
Effect of nitrogen mustard, 6-mercaptopurine and cortisone on reactions of dermal connective tissue of rabbits to the streptococcal cell wall.
    The American journal of pathology, 1965, Volume: 47, Issue:4

    Topics: Animals; Connective Tissue; Cortisone; Granuloma; Hypersensitivity, Delayed; Mechlorethamine; Mercap

1965