Page last updated: 2024-10-30

mechlorethamine and Cornea Injuries

mechlorethamine has been researched along with Cornea Injuries in 6 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
" The effects of NM-exposure to eyes may include irritation, redness, inflammation, fibrosis, epithelial degradation, blurred vision, partial/complete blindness, which may be temporary or permanent, depending on the route, duration, and dosage of exposure."1.72Effect of dexamethasone treatment at variable therapeutic windows in reversing nitrogen mustard-induced corneal injuries in rabbit ocular in vivo model. ( Agarwal, C; Agarwal, R; Ammar, DA; Goswami, DG; Kant, R; Mishra, N; Petrash, JM; Tewari-Singh, N, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Goswami, DG2
Mishra, N1
Kant, R2
Agarwal, C1
Ammar, DA2
Petrash, JM2
Tewari-Singh, N2
Agarwal, R2
An, S1
Shen, X1
Anwar, K1
Ashraf, M1
Lee, H1
Koganti, R1
Ghassemi, M1
Djalilian, AR1
Kaluzhny, Y1
Kinuthia, MW1
Lapointe, AM1
Truong, T1
Klausner, M1
Hayden, P1
Charkoftaki, G1
Jester, JV1
Thompson, DC1
Vasiliou, V1
Eveleth, DD1
Eveleth, JJ1
Subramaniam, A1
Hahn, R1
Zhou, P1
Gordon, MK1
Bradshaw, RA1
Kumar, D1
Enzenauer, RW1

Other Studies

6 other studies available for mechlorethamine and Cornea Injuries

ArticleYear
Effect of dexamethasone treatment at variable therapeutic windows in reversing nitrogen mustard-induced corneal injuries in rabbit ocular in vivo model.
    Toxicology and applied pharmacology, 2022, 02-15, Volume: 437

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Corneal Injuries; Dexamethasone; Irritants; Male; Mec

2022
Therapeutic Potential of Mesenchymal Stem Cell-Secreted Factors on Delay in Corneal Wound Healing by Nitrogen Mustard.
    International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19

    Topics: Animals; Corneal Injuries; Culture Media, Conditioned; Endothelial Cells; Mechlorethamine; Mesenchym

2022
Oxidative stress in corneal injuries of different origin: Utilization of 3D human corneal epithelial tissue model.
    Experimental eye research, 2020, Volume: 190

    Topics: Alkylating Agents; Cell Survival; Corneal Injuries; Cytokines; Dry Eye Syndromes; Electric Impedance

2020
Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.
    The ocular surface, 2018, Volume: 16, Issue:1

    Topics: Animals; Ceramides; Chemical Warfare Agents; Chromatography, Liquid; Cornea; Corneal Injuries; Digly

2018
An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures.
    Investigative ophthalmology & visual science, 2018, 09-04, Volume: 59, Issue:11

    Topics: ADAM17 Protein; Animals; Chemical Warfare Agents; Cornea; Corneal Injuries; DNA Damage; Fibroblast G

2018
Acute corneal injury in rabbits following nitrogen mustard ocular exposure.
    Experimental and molecular pathology, 2019, Volume: 110

    Topics: Acute Disease; Animals; Chemical Warfare Agents; Cornea; Corneal Injuries; Cyclooxygenase 2; Humans;

2019