mechlorethamine has been researched along with Colonic Neoplasms in 30 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies were performed in human colon cancer HCT-116 cells and murine embryonic fibroblasts (MEF) with intact versus disrupted p21 genes." | 1.30 | Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard. ( Chang, JK; Duba, D; Fan, S; Fornace, AJ; O'Connor, PM; Smith, ML, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (80.00) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharaf el dein, O | 1 |
| Gallerne, C | 1 |
| Brenner, C | 1 |
| Lemaire, C | 1 |
| HIGGINS, GA | 1 |
| SERLIN, O | 1 |
| HUGHES, F | 1 |
| DWIGHT, RW | 1 |
| HENNE, HF | 1 |
| ETALA, E | 1 |
| SOFIA, V | 1 |
| ROMERO, LM | 1 |
| FUJIMORI, M | 1 |
| SAKAUCHI, G | 1 |
| IZUO, M | 1 |
| ABE, C | 1 |
| MORITA, S | 1 |
| NASHIMOTO, T | 1 |
| ISHIKAWA, S | 1 |
| SADMITSU, H | 1 |
| KAWAI, T | 1 |
| SHINGLETON, WW | 1 |
| PARKER, RT | 1 |
| MRAZEK, R | 1 |
| ECONOMOU, E | 1 |
| MCDONALD, G | 1 |
| SLAUGHTER, D | 1 |
| COLE, WH | 1 |
| GOLDGRABER, MB | 1 |
| KIRSNER, JB | 1 |
| FRIEDMAN, BI | 1 |
| SAENGER, EL | 1 |
| KREINDLER, MS | 1 |
| GROSSI, CE | 4 |
| COLE, DR | 5 |
| ROUSSELOT, LM | 5 |
| Cohn, I | 1 |
| Gilbert, JM | 1 |
| Markman, M | 1 |
| Presant, CA | 1 |
| Carr, D | 1 |
| Kohn, KW | 1 |
| Orr, A | 1 |
| O'Connor, PM | 2 |
| Guziec, LJ | 1 |
| Guziec, FS | 1 |
| Fan, S | 1 |
| Chang, JK | 1 |
| Smith, ML | 1 |
| Duba, D | 1 |
| Fornace, AJ | 1 |
| Boddie, AW | 1 |
| Constantinou, A | 1 |
| Williams, C | 1 |
| Reed, A | 1 |
| Futscher, BW | 2 |
| Pieper, RO | 1 |
| Dalton, WS | 1 |
| Erickson, LC | 2 |
| Knock, FE | 1 |
| Galt, RM | 1 |
| Oester, YT | 1 |
| Sylvester, R | 1 |
| Griffen, WO | 1 |
| Humphrey, L | 1 |
| Sosin, H | 1 |
| Kenis, Y | 1 |
| Hill, GJ | 1 |
| Larsen, RR | 1 |
| Habib, MA | 1 |
| Donaldson, JC | 1 |
| Burningham, RA | 1 |
| Conte, AJ | 2 |
| Gonzalez, EM | 3 |
| Pasternack, BS | 1 |
| Lefkowitz, ER | 1 |
| Slattery, J | 1 |
3 reviews available for mechlorethamine and Colonic Neoplasms
| Article | Year |
|---|---|
[CHEMOTHERAPY BY PERFUSION FOR CANCER OF THE STOMACH AND COLON].
Topics: Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Flox | 1963 |
The prognosis and management of recurrent abdominal malignancies.
Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Ca | 1969 |
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
4 trials available for mechlorethamine and Colonic Neoplasms
| Article | Year |
|---|---|
Adjuvant chemotherapy of large bowel cancer.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Colonic Neoplasms; Drug Therapy, Combination; Floxu | 1982 |
Newer techniques in cancer chemotherapy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bleomycin; Bone Marrow Transplantation; Carcinoma; Ce | 1984 |
Intraluminal chemotherapy (HN2 or 5-FU) adjuvant to operation for cancer of the colon and rectum. II. Follow-up report of 97 cases.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Neoplasms; Fluorouracil; Follow-Up Studies; Humans; M | 1967 |
A five year progress report on the effectiveness of intraluminal chemotherapy (5-fluorouracil) adjuvant to surgery for colorectal cancer.
Topics: Carcinoma; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections, Intravenous; Male; Mechloret | 1968 |
23 other studies available for mechlorethamine and Colonic Neoplasms
| Article | Year |
|---|---|
Increased expression of VDAC1 sensitizes carcinoma cells to apoptosis induced by DNA cross-linking agents.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Pro | 2012 |
The Veterans Administration surgical Adjuvant Group--interim report.
Topics: Antineoplastic Agents; Colonic Neoplasms; Humans; Lung Neoplasms; Mechlorethamine; Nitrogen Mustard | 1962 |
[Results of supplementary chemotherapy in surgically treated bronchial, stomach and colon carcinoma].
Topics: Bronchial Neoplasms; Colonic Neoplasms; Cyclophosphamide; Humans; Intestinal Neoplasms; Mechloretham | 1962 |
STUDIES ON REGIONAL PERFUSION AND INTRA-ARTERIAL INFUSION FOR CANCER CHEMOTHERAPY.
Topics: Antineoplastic Agents; Breast Neoplasms; Celiac Artery; Chemotherapy, Cancer, Regional Perfusion; Co | 1964 |
ABDOMINAL PERFUSION FOR CANCER CHEMOTHERAPY USING HYPOTHERMIA AND HYPERTHERMIA.
Topics: Abdomen; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cycloph | 1964 |
PROPHYLACTIC AND ADJUVANT USE OF CHEMOTHERAPY IN THE SURGICAL TREATMENT OF CANCER.
Topics: Breast Neoplasms; Colonic Neoplasms; Humans; Mechlorethamine; Neoplasms; Rectal Neoplasms | 1964 |
CARCINOMA OF THE COLON IN ULCERATIVE COLITIS.
Topics: Aged; Aging; Cell Biology; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Fluorouracil; Humans; Me | 1964 |
ENDOREDUPLICATION IN LEUCOCYTE CHROMOSOMES. PRELIMINARY REPORT OF ITS RELATION TO CANCER AND WHOLE-BODY IRRADIATION.
Topics: Breast Neoplasms; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Cobalt Isotopes; Coloni | 1964 |
INTRALUMINAL CHEMOTHERAPY WITH NITROGEN MUSTARD IN SIMULATED CANCER OF THE COLON IN THE RAT.
Topics: Absorption; Carcinoma; Carcinoma 256, Walker; Cecal Neoplasms; Colonic Neoplasms; Mechlorethamine; N | 1964 |
Intraluminal injection of nitrogen mustard as adjuvant chemotherapy in treatment of cancer of the colon and rectum.
Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Rect | 1962 |
[Indications for the Babcock-Bacon operation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colonic Neoplasms; Doxorubicin; Humans; L | 1952 |
Implantation in cancer of the colon.
Topics: Animals; Antisepsis; Carcinoma, Brown-Pearce; Colonic Neoplasms; Dextrans; Dimethyl Sulfoxide; In Vi | 1967 |
Amphotericin B (Fungizone R) enhancement of nitrogen mustard uptake by human tumor cells.
Topics: Amphotericin B; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Cells, Cultured; C | 1980 |
Synthesis and DNA-sequence selectivity of a series of mono- and difunctional 9-aminoacridine nitrogen mustards.
Topics: Acridines; Alkylation; Base Sequence; Binding Sites; Colonic Neoplasms; DNA; Guanine; Humans; Interc | 1994 |
Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Cycle; Chloramphenicol O-Ace | 1997 |
Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells.
Topics: Adenosine Triphosphate; Ammonia; Antineoplastic Agents, Alkylating; Apoptosis; Cell Cycle; Chromatog | 1998 |
Gene-specific DNA interstrand cross-links produced by nitrogen mustard in the human tumor cell line Colo320HSR.
Topics: Blotting, Southern; Colonic Neoplasms; DNA Damage; DNA Probes; DNA Repair; DNA, Neoplasm; Genes, myc | 1992 |
Changes in c-myc and c-fos expression in a human tumor cell line following exposure to bifunctional alkylating agents.
Topics: Blotting, Northern; Cell Line; Colonic Neoplasms; Gene Expression; Humans; Kinetics; Mechlorethamine | 1990 |
Inhibition of DNA polymerases and neoplastic cells by selected SH inhibitors.
Topics: Animals; Antineoplastic Agents; Arsenicals; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Ch | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; | 1972 |
Hodgkin's disease of the colon.
Topics: Adult; Biopsy; Colonic Neoplasms; Female; Hodgkin Disease; Humans; Lymph Nodes; Mechlorethamine; Pre | 1973 |
Perforation of transverse colon in a patient with Hodgkin's disease.
Topics: Adolescent; Colonic Neoplasms; Cyclophosphamide; Female; Hodgkin Disease; Humans; In Vitro Technique | 1965 |
Intraluminal chemotherapy adjuvant (HN2 or 5-FU) to operation for cancer of the colon and rectum. Follow-up report of 83 cases.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Humans; Mechlorethamine; Middle | 1965 |