Page last updated: 2024-10-30

mechlorethamine and Chronic Lung Injury

mechlorethamine has been researched along with Chronic Lung Injury in 6 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"Acute edematous lung injury is associated with a marked increase in the number of granulocytes in the alveoli and microvasculature of the lung."1.26Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals. ( McMurtry, I; Repine, JE; Shasby, DM; Shasby, SS; Tate, RM; Vanbenthuysen, KM, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Solopov, P1
Biancatelli, RMLC1
Marinova, M1
Dimitropoulou, C1
Catravas, JD1
Smith, LC1
Venosa, A3
Gow, AJ4
Laskin, JD4
Laskin, DL4
Sunil, VR1
Vayas, KN1
Cervelli, JA1
Ebramova, EV1
Goedken, M1
Malaviya, R3
Choi, H1
Hall, L1
Sinko, PJ1
Shasby, DM1
Vanbenthuysen, KM1
Tate, RM1
Shasby, SS1
McMurtry, I1
Repine, JE1

Other Studies

6 other studies available for mechlorethamine and Chronic Lung Injury

ArticleYear
The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice.
    International journal of molecular sciences, 2020, Jul-03, Volume: 21, Issue:13

    Topics: Animals; Biomarkers; Disease Models, Animal; Extracellular Matrix Proteins; HSP90 Heat-Shock Protein

2020
Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard.
    Annals of the New York Academy of Sciences, 2020, Volume: 1480, Issue:1

    Topics: Animals; Chemical Warfare Agents; Gene Expression Regulation; Inflammation; Lung Injury; Macrophages

2020
Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 11-01, Volume: 166, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Female; Lung Injury; Macrophage Activation; Macrophages, Alve

2018
Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.
    American journal of respiratory cell and molecular biology, 2016, Volume: 54, Issue:3

    Topics: Animals; Biomarkers; Cytokines; Disease Models, Animal; Gene Expression Regulation; Inflammation Med

2016
Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.
    Toxicology and applied pharmacology, 2012, Dec-15, Volume: 265, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Drug Interactions; Enzyme Inhibitors; Fibrosis; Guanidines; H

2012
Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.
    The American review of respiratory disease, 1982, Volume: 125, Issue:4

    Topics: Agranulocytosis; Animals; Free Radicals; Granulocytes; Granulomatous Disease, Chronic; Lung; Lung In

1982