mechlorethamine has been researched along with Carcinoma 256, Walker in 42 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In rats dosed with SR 4233 in vivo, significantly higher levels of 8-hydroxydeoxyguanosine could be detected in liver, compared to vehicle-dosed controls." | 1.29 | Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions. ( Cahill, A; Jenkins, TC; Pickering, P; White, IN, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (95.24) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MCDONALD, GO | 1 |
| CRUZ, EP | 1 |
| COLE, WH | 1 |
| MCNAIR, TJ | 1 |
| WIBIN, FA | 1 |
| HOPPE, ET | 1 |
| SCHMIDT, JL | 1 |
| DEPEYSTER, JA | 1 |
| NYHAN, WL | 1 |
| LOH HOEHN-SARIC, E | 1 |
| INCH, WR | 2 |
| McCREDIE, JA | 2 |
| AGOSTINO, D | 2 |
| CLIFFTON, EE | 2 |
| DASGUPTA, T | 1 |
| PIETRA, G | 1 |
| SCORTECCI, V | 1 |
| SICE, J | 1 |
| IWAMOTO, RH | 1 |
| ACTON, EM | 1 |
| ROSS, LO | 1 |
| SKINNER, WA | 1 |
| BAKER, BR | 1 |
| GOODMAN, L | 4 |
| TSOU, KC | 1 |
| SU, HC | 1 |
| MCKIBBIN, B | 1 |
| DEGRAW, J | 1 |
| FARPOUR, A | 1 |
| FISHER, B | 1 |
| FISHER, ER | 1 |
| GROSSI, CE | 1 |
| COLE, DR | 1 |
| ROUSSELOT, LM | 1 |
| ZIMMER, H | 1 |
| SILL, AD | 1 |
| BURKE, WJ | 1 |
| BROWN, JE | 1 |
| WEATHERBEE, C | 1 |
| CURTIS, DH | 1 |
| SMITH, HE | 1 |
| COOK, SL | 1 |
| ZIMEL, H | 1 |
| MACRINEANU, A | 1 |
| MARTINEZ, AP | 2 |
| LEE, WW | 2 |
| Cahill, A | 2 |
| Jenkins, TC | 1 |
| Pickering, P | 1 |
| White, IN | 3 |
| Merriman, RL | 1 |
| Sladek, NE | 2 |
| Suzanger, M | 1 |
| Mattocks, AR | 1 |
| Bailey, E | 1 |
| Farmer, PB | 1 |
| Connors, TA | 1 |
| Dean, SW | 2 |
| Johnson, AB | 1 |
| Tew, KD | 4 |
| Grunicke, H | 3 |
| Doppler, W | 2 |
| Hofmann, J | 3 |
| Lindner, H | 1 |
| Maly, K | 2 |
| Oberhuber, H | 1 |
| Ringsdorf, H | 1 |
| Roberts, JJ | 1 |
| Moy, BC | 1 |
| Helliger, W | 2 |
| Hermann, BJ | 2 |
| Höck, W | 2 |
| Puschendorf, B | 2 |
| Buller, AL | 1 |
| Clapper, ML | 1 |
| Gibson, NW | 1 |
| Everett, J | 1 |
| Goldenberg, GJ | 1 |
| Sinha, BK | 1 |
| Terent'eva, TG | 1 |
| Fomina, IP | 1 |
| Navashin, SM | 1 |
| Foster, AB | 1 |
| Jarman, M | 1 |
| Ross, WC | 1 |
| Tisdale, MJ | 1 |
| Elson, LA | 1 |
| Cambanis, A | 1 |
| Dobre, V | 1 |
| Niculescu-Duvăz, I | 1 |
| Smith, GM | 1 |
| Garvie, WH | 2 |
| Hellmann, K | 1 |
| Tucker, DF | 1 |
42 other studies available for mechlorethamine and Carcinoma 256, Walker
| Article | Year |
|---|---|
The effect of cancer inhibitor drugs on the take of Walker carcinosarcoma 256 in rats.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Mechlorethamine; Neoplasms, Experimental; Nit | 1957 |
Antitumor action of several new piperazine derivatives compared to certain standard anticancer agents.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Fluorouracil; Humans; Mechloretham | 1963 |
Effects of nitrogen mustards on the incorporation of amino acids into the proteins of tumors and other tissues; the mustard derivative of serine.
Topics: Amino Acids; Animals; Carcinoma; Carcinoma 256, Walker; Humans; Mechlorethamine; Methionine; Mustard | 1963 |
Effect of aging aqueous nitrogen mustard on white blood cell count, body weight, and Walker 256 tumor in the rat.
Topics: Animals; Body Weight; Carcinoma; Carcinoma 256, Walker; Leukocyte Count; Mechlorethamine; Rats | 1963 |
Effect of wound irrigation with nitrogen mustard or Clorpactin XCB on local recurrence of rat and mouse tumors.
Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Carcinoma; Carcinoma 256, Walker; Mechlorethamine | 1963 |
Decrease in pulmonary metastases: potentiation of nitrogen mustard effect by heparin and fibrinolysin.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Fibrinolysin; Heparin; Lung Neoplasms; Mechlorethamine; N | 1963 |
CARCINOSTATIC PROPERTIES OF MECHLORETHAMINE OXIDE.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Mechlorethamine; Neoplasm Metastasis; Pharmacology; Rats; | 1964 |
POTENTIAL ANTICANCER AGENTS. LXXIX. AROMATIC NITROGEN MUSTARDS DERIVED FROM CYSTEINE.
Topics: Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Cysteine; Mechlo | 1963 |
SYNTHESIS OF POSSIBLE CANCER CHEMOTHERAPEUTIC COMPOUNDS BASED ON ENZYME APPROACH. V. TETRAZOLIUM NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia; Leukemia, Experiment | 1963 |
DESTRUCTION OF MALIGNANT CELLS IN PERITONEAL CAVITY. EXPERIMENTAL USE OF A CHEMOTHERAPEUTIC AGENT.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Iatrogenic Disease; Injections; In | 1964 |
ALKYLATING AGENTS DERIVED FROM INDOLES. IV. SYNTHESIS OF THE 5-NITROGEN MUSTARD OF INDOLE-3-CARBOXYLIC ACID.
Topics: Alkylating Agents; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Indoles; Mechloretha | 1964 |
TRANSPLANTABLE LUNG CANCER IN RATS. EFFECT OF TREATMENT.
Topics: Animals; Blood; Carcinoma; Carcinoma 256, Walker; Fibrinolysin; Heparin; Lung Neoplasms; Mechloretha | 1964 |
EFFECT OF EXPERIMENTAL PERFUSION UPON THE BIOLOGIC AND PATHOLOGIC BEHAVIOR OF TUMOR.
Topics: Biological Products; Carcinoma; Carcinoma 256, Walker; Chemotherapy, Cancer, Regional Perfusion; Lun | 1964 |
INTRALUMINAL CHEMOTHERAPY WITH NITROGEN MUSTARD IN SIMULATED CANCER OF THE COLON IN THE RAT.
Topics: Absorption; Carcinoma; Carcinoma 256, Walker; Cecal Neoplasms; Colonic Neoplasms; Mechlorethamine; N | 1964 |
POTENTIAL ANTICANCER AGENTS. IV. HETEROCYCLIC PHOSPHORAMIDE NITROGEN MUSTARDS.
Topics: Antineoplastic Agents; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Neoplasms; | 1964 |
CYANO ANALOGS OF PHENOLIC NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia L1210; Mechlorethamin | 1964 |
ETHYL N-BENZYLLEUCINATE NITROGEN MUSTARD.
Topics: Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Nitrogen Mustard Compo | 1964 |
[RESEARCH ON THE ANTIBLASTIC ACTION OF A NITROGEN MUSTARD OF THE URETHANE TYPE BOUND TO HYDROCORTISONE].
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Hydrocortisone; Mammary Neoplas | 1964 |
NITROGEN MUSTARDS DERIVED FROM 3,4-DIHYDRO-2, 4-DIOXO-1(2H)-PYRIMIDINEPROPIONIC AND -BUTYRIC ACIDS.
Topics: Butyrates; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Nitrogen Mu | 1965 |
Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aerobiosis; Animals; Antineoplastic Agents; Biotransformation; Carcinom | 1995 |
Cytotoxic activity of mechlorethamine and melphalan against cultured tumor cells: potentiation by caffeine.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma 256, Walker; Cells, Cultured; Drug Synergism; Ly | 1978 |
Reductive activation of N-oxides to cause DNA strand breakage in cell lines in vitro.
Topics: Aerobiosis; Anaerobiosis; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Line; Cell Tra | 1991 |
Reduction of nitromin to nitrogen mustard: unscheduled DNA synthesis in aerobic or anaerobic rat hepatocytes, JB1, BL8 and Walker carcinoma cell lines.
Topics: Aerobiosis; Anaerobiosis; Animals; Antineoplastic Agents; Carcinoma 256, Walker; DNA Repair; In Vitr | 1989 |
A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas.
Topics: Animals; Carcinoma 256, Walker; Cell Line; Cross-Linking Reagents; DNA; Dose-Response Relationship, | 1986 |
Plasma membrane as target of alkylating agents.
Topics: Adenosine Triphosphatases; Alkylating Agents; Animals; Calcium Channel Blockers; Carcinoma 256, Walk | 1985 |
Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines.
Topics: Adenosine Monophosphate; Animals; Antigens, Nuclear; Carcinoma 256, Walker; Cell Line; Chromatograph | 1985 |
Differential sensitivity of histone acetylation in nitrogen-mustard sensitive and resistant cells. Relation to drug uptake, formation and repair of DNA-interstrand cross-links.
Topics: Acetylation; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyclophosphamid | 1988 |
Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Chlorambucil; Cytosol; Drug Resistance; Glutathio | 1987 |
Alkylating antitumor agents reduce histone acetyl-transferase activity.
Topics: Acetylation; Acetyltransferases; Animals; Butyrates; Butyric Acid; Carcinoma 256, Walker; Carcinoma, | 1986 |
Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity.
Topics: Animals; Carcinoma 256, Walker; Cell Line; Dacarbazine; DNA, Neoplasm; Drug Resistance; Mammary Neop | 1986 |
Walker carcinosarcoma 256 in study of anticancer agents. II. Results.
Topics: Acetates; Animals; Antineoplastic Agents; Azirines; Benzene; Benzoates; Butyrates; Carcinoma 256, Wa | 1966 |
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo.
Topics: Acrolein; Animals; Biological Assay; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Cyclophosph | 1973 |
Nitrogen mustard sensitivity and choline transport in Walker 256 carcinosarcoma cells in vitro.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Carbon Radioisotopes; Carcinoma 256, Wa | 1973 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As | 1970 |
N-(2-chloroethyl)-N-(2-hydroxyethyl)arylamines. Possible intermediates to potential carcinolytic agents bearing dissimilar reactive functions.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Lethal Dose 50; Mechloreth | 1972 |
DL-willardiine mustard.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Culture Techniques; Leukemia L1210 | 1968 |
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlor | 1968 |
Potential anticancer agents. V. New aromatic nitrogen mustards related to 3-[N,N-bis(2-chloroethyl)amino]-4-methylbenzoic acid.
Topics: Amides; Animals; Antineoplastic Agents; Benzoates; Carcinoma 256, Walker; Chemical Phenomena; Chemis | 1969 |
A comparison of the effects of cytotoxic agents on the Walker 256 tumour growing in the rat and at the hamster cheek pouch.
Topics: Animals; Carcinoma 256, Walker; Cheek; Cricetinae; Female; Male; Mechlorethamine; Methotrexate; Neop | 1969 |
The action of protamine derivatives and nitrogen mustard on the growth of the Walker 256 rat carcinoma.
Topics: Animals; Carcinoma 256, Walker; Drug Synergism; Injections, Intraperitoneal; Mechlorethamine; Protam | 1965 |
Localization of tumours and drugs on the chorio-allantoic membrane of the chick embryo.
Topics: Animals; Carcinoma 256, Walker; Chick Embryo; Cyclophosphamide; Extraembryonic Membranes; Mechloreth | 1965 |
Studies on induced tumour resistance.
Topics: Animals; Antibody Formation; Carcinoma 256, Walker; Mechlorethamine; Neoplasms; Rats | 1966 |