mechlorethamine has been researched along with Carcinoma 256, Walker in 42 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
Excerpt | Relevance | Reference |
---|---|---|
" In rats dosed with SR 4233 in vivo, significantly higher levels of 8-hydroxydeoxyguanosine could be detected in liver, compared to vehicle-dosed controls." | 1.29 | Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions. ( Cahill, A; Jenkins, TC; Pickering, P; White, IN, 1995) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 40 (95.24) | 18.7374 |
1990's | 2 (4.76) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
MCDONALD, GO | 1 |
CRUZ, EP | 1 |
COLE, WH | 1 |
MCNAIR, TJ | 1 |
WIBIN, FA | 1 |
HOPPE, ET | 1 |
SCHMIDT, JL | 1 |
DEPEYSTER, JA | 1 |
NYHAN, WL | 1 |
LOH HOEHN-SARIC, E | 1 |
INCH, WR | 2 |
McCREDIE, JA | 2 |
AGOSTINO, D | 2 |
CLIFFTON, EE | 2 |
DASGUPTA, T | 1 |
PIETRA, G | 1 |
SCORTECCI, V | 1 |
SICE, J | 1 |
IWAMOTO, RH | 1 |
ACTON, EM | 1 |
ROSS, LO | 1 |
SKINNER, WA | 1 |
BAKER, BR | 1 |
GOODMAN, L | 4 |
TSOU, KC | 1 |
SU, HC | 1 |
MCKIBBIN, B | 1 |
DEGRAW, J | 1 |
FARPOUR, A | 1 |
FISHER, B | 1 |
FISHER, ER | 1 |
GROSSI, CE | 1 |
COLE, DR | 1 |
ROUSSELOT, LM | 1 |
ZIMMER, H | 1 |
SILL, AD | 1 |
BURKE, WJ | 1 |
BROWN, JE | 1 |
WEATHERBEE, C | 1 |
CURTIS, DH | 1 |
SMITH, HE | 1 |
COOK, SL | 1 |
ZIMEL, H | 1 |
MACRINEANU, A | 1 |
MARTINEZ, AP | 2 |
LEE, WW | 2 |
Cahill, A | 2 |
Jenkins, TC | 1 |
Pickering, P | 1 |
White, IN | 3 |
Merriman, RL | 1 |
Sladek, NE | 2 |
Suzanger, M | 1 |
Mattocks, AR | 1 |
Bailey, E | 1 |
Farmer, PB | 1 |
Connors, TA | 1 |
Dean, SW | 2 |
Johnson, AB | 1 |
Tew, KD | 4 |
Grunicke, H | 3 |
Doppler, W | 2 |
Hofmann, J | 3 |
Lindner, H | 1 |
Maly, K | 2 |
Oberhuber, H | 1 |
Ringsdorf, H | 1 |
Roberts, JJ | 1 |
Moy, BC | 1 |
Helliger, W | 2 |
Hermann, BJ | 2 |
Höck, W | 2 |
Puschendorf, B | 2 |
Buller, AL | 1 |
Clapper, ML | 1 |
Gibson, NW | 1 |
Everett, J | 1 |
Goldenberg, GJ | 1 |
Sinha, BK | 1 |
Terent'eva, TG | 1 |
Fomina, IP | 1 |
Navashin, SM | 1 |
Foster, AB | 1 |
Jarman, M | 1 |
Ross, WC | 1 |
Tisdale, MJ | 1 |
Elson, LA | 1 |
Cambanis, A | 1 |
Dobre, V | 1 |
Niculescu-Duvăz, I | 1 |
Smith, GM | 1 |
Garvie, WH | 2 |
Hellmann, K | 1 |
Tucker, DF | 1 |
42 other studies available for mechlorethamine and Carcinoma 256, Walker
Article | Year |
---|---|
The effect of cancer inhibitor drugs on the take of Walker carcinosarcoma 256 in rats.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Mechlorethamine; Neoplasms, Experimental; Nit | 1957 |
Antitumor action of several new piperazine derivatives compared to certain standard anticancer agents.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Fluorouracil; Humans; Mechloretham | 1963 |
Effects of nitrogen mustards on the incorporation of amino acids into the proteins of tumors and other tissues; the mustard derivative of serine.
Topics: Amino Acids; Animals; Carcinoma; Carcinoma 256, Walker; Humans; Mechlorethamine; Methionine; Mustard | 1963 |
Effect of aging aqueous nitrogen mustard on white blood cell count, body weight, and Walker 256 tumor in the rat.
Topics: Animals; Body Weight; Carcinoma; Carcinoma 256, Walker; Leukocyte Count; Mechlorethamine; Rats | 1963 |
Effect of wound irrigation with nitrogen mustard or Clorpactin XCB on local recurrence of rat and mouse tumors.
Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Carcinoma; Carcinoma 256, Walker; Mechlorethamine | 1963 |
Decrease in pulmonary metastases: potentiation of nitrogen mustard effect by heparin and fibrinolysin.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Fibrinolysin; Heparin; Lung Neoplasms; Mechlorethamine; N | 1963 |
CARCINOSTATIC PROPERTIES OF MECHLORETHAMINE OXIDE.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Mechlorethamine; Neoplasm Metastasis; Pharmacology; Rats; | 1964 |
POTENTIAL ANTICANCER AGENTS. LXXIX. AROMATIC NITROGEN MUSTARDS DERIVED FROM CYSTEINE.
Topics: Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Cysteine; Mechlo | 1963 |
SYNTHESIS OF POSSIBLE CANCER CHEMOTHERAPEUTIC COMPOUNDS BASED ON ENZYME APPROACH. V. TETRAZOLIUM NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia; Leukemia, Experiment | 1963 |
DESTRUCTION OF MALIGNANT CELLS IN PERITONEAL CAVITY. EXPERIMENTAL USE OF A CHEMOTHERAPEUTIC AGENT.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Iatrogenic Disease; Injections; In | 1964 |
ALKYLATING AGENTS DERIVED FROM INDOLES. IV. SYNTHESIS OF THE 5-NITROGEN MUSTARD OF INDOLE-3-CARBOXYLIC ACID.
Topics: Alkylating Agents; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Indoles; Mechloretha | 1964 |
TRANSPLANTABLE LUNG CANCER IN RATS. EFFECT OF TREATMENT.
Topics: Animals; Blood; Carcinoma; Carcinoma 256, Walker; Fibrinolysin; Heparin; Lung Neoplasms; Mechloretha | 1964 |
EFFECT OF EXPERIMENTAL PERFUSION UPON THE BIOLOGIC AND PATHOLOGIC BEHAVIOR OF TUMOR.
Topics: Biological Products; Carcinoma; Carcinoma 256, Walker; Chemotherapy, Cancer, Regional Perfusion; Lun | 1964 |
INTRALUMINAL CHEMOTHERAPY WITH NITROGEN MUSTARD IN SIMULATED CANCER OF THE COLON IN THE RAT.
Topics: Absorption; Carcinoma; Carcinoma 256, Walker; Cecal Neoplasms; Colonic Neoplasms; Mechlorethamine; N | 1964 |
POTENTIAL ANTICANCER AGENTS. IV. HETEROCYCLIC PHOSPHORAMIDE NITROGEN MUSTARDS.
Topics: Antineoplastic Agents; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Neoplasms; | 1964 |
CYANO ANALOGS OF PHENOLIC NITROGEN MUSTARDS.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia L1210; Mechlorethamin | 1964 |
ETHYL N-BENZYLLEUCINATE NITROGEN MUSTARD.
Topics: Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Nitrogen Mustard Compo | 1964 |
[RESEARCH ON THE ANTIBLASTIC ACTION OF A NITROGEN MUSTARD OF THE URETHANE TYPE BOUND TO HYDROCORTISONE].
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Hydrocortisone; Mammary Neoplas | 1964 |
NITROGEN MUSTARDS DERIVED FROM 3,4-DIHYDRO-2, 4-DIOXO-1(2H)-PYRIMIDINEPROPIONIC AND -BUTYRIC ACIDS.
Topics: Butyrates; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Mechlorethamine; Nitrogen Mu | 1965 |
Genotoxic effects of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) and nitrogen mustard-N-oxide (nitromin) in Walker carcinoma cells under aerobic and hypoxic conditions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aerobiosis; Animals; Antineoplastic Agents; Biotransformation; Carcinom | 1995 |
Cytotoxic activity of mechlorethamine and melphalan against cultured tumor cells: potentiation by caffeine.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma 256, Walker; Cells, Cultured; Drug Synergism; Ly | 1978 |
Reductive activation of N-oxides to cause DNA strand breakage in cell lines in vitro.
Topics: Aerobiosis; Anaerobiosis; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Line; Cell Tra | 1991 |
Reduction of nitromin to nitrogen mustard: unscheduled DNA synthesis in aerobic or anaerobic rat hepatocytes, JB1, BL8 and Walker carcinoma cell lines.
Topics: Aerobiosis; Anaerobiosis; Animals; Antineoplastic Agents; Carcinoma 256, Walker; DNA Repair; In Vitr | 1989 |
A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas.
Topics: Animals; Carcinoma 256, Walker; Cell Line; Cross-Linking Reagents; DNA; Dose-Response Relationship, | 1986 |
Plasma membrane as target of alkylating agents.
Topics: Adenosine Triphosphatases; Alkylating Agents; Animals; Calcium Channel Blockers; Carcinoma 256, Walk | 1985 |
Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines.
Topics: Adenosine Monophosphate; Animals; Antigens, Nuclear; Carcinoma 256, Walker; Cell Line; Chromatograph | 1985 |
Differential sensitivity of histone acetylation in nitrogen-mustard sensitive and resistant cells. Relation to drug uptake, formation and repair of DNA-interstrand cross-links.
Topics: Acetylation; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyclophosphamid | 1988 |
Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Chlorambucil; Cytosol; Drug Resistance; Glutathio | 1987 |
Alkylating antitumor agents reduce histone acetyl-transferase activity.
Topics: Acetylation; Acetyltransferases; Animals; Butyrates; Butyric Acid; Carcinoma 256, Walker; Carcinoma, | 1986 |
Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity.
Topics: Animals; Carcinoma 256, Walker; Cell Line; Dacarbazine; DNA, Neoplasm; Drug Resistance; Mammary Neop | 1986 |
Walker carcinosarcoma 256 in study of anticancer agents. II. Results.
Topics: Acetates; Animals; Antineoplastic Agents; Azirines; Benzene; Benzoates; Butyrates; Carcinoma 256, Wa | 1966 |
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo.
Topics: Acrolein; Animals; Biological Assay; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Cyclophosph | 1973 |
Nitrogen mustard sensitivity and choline transport in Walker 256 carcinosarcoma cells in vitro.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Carbon Radioisotopes; Carcinoma 256, Wa | 1973 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As | 1970 |
N-(2-chloroethyl)-N-(2-hydroxyethyl)arylamines. Possible intermediates to potential carcinolytic agents bearing dissimilar reactive functions.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Lethal Dose 50; Mechloreth | 1972 |
DL-willardiine mustard.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma 256, Walker; Culture Techniques; Leukemia L1210 | 1968 |
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlor | 1968 |
Potential anticancer agents. V. New aromatic nitrogen mustards related to 3-[N,N-bis(2-chloroethyl)amino]-4-methylbenzoic acid.
Topics: Amides; Animals; Antineoplastic Agents; Benzoates; Carcinoma 256, Walker; Chemical Phenomena; Chemis | 1969 |
A comparison of the effects of cytotoxic agents on the Walker 256 tumour growing in the rat and at the hamster cheek pouch.
Topics: Animals; Carcinoma 256, Walker; Cheek; Cricetinae; Female; Male; Mechlorethamine; Methotrexate; Neop | 1969 |
The action of protamine derivatives and nitrogen mustard on the growth of the Walker 256 rat carcinoma.
Topics: Animals; Carcinoma 256, Walker; Drug Synergism; Injections, Intraperitoneal; Mechlorethamine; Protam | 1965 |
Localization of tumours and drugs on the chorio-allantoic membrane of the chick embryo.
Topics: Animals; Carcinoma 256, Walker; Chick Embryo; Cyclophosphamide; Extraembryonic Membranes; Mechloreth | 1965 |
Studies on induced tumour resistance.
Topics: Animals; Antibody Formation; Carcinoma 256, Walker; Mechlorethamine; Neoplasms; Rats | 1966 |