mechlorethamine has been researched along with Cancer, Radiation-Induced in 36 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose." | 7.85 | Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017) |
| " The additional use of mechlorethamine or oral psoralen plus UV-A, but not radiation, was significantly associated with the development of basal cell carcinoma and squamous cell carcinoma, but not malignant melanoma." | 4.79 | Malignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation. ( Braverman, IM; Feldman, AM; Kacinski, BM; Licata, AG; Wilson, LD, 1995) |
| "Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose." | 3.85 | Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017) |
| "Ductal invasive carcinoma and ductal carcinoma in situ represented, respectively, 51 cases (71%) and 14 cases (19%)." | 1.38 | Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option. ( Belin, L; Bollet, MA; Campana, F; Decaudin, D; Fourquet, A; Haberer, S; Kirova, YM; Le Scodan, R; Moisson, P; Pierga, JY; Reyal, F; Savignoni, A; Stevens, D, 2012) |
| "Relative risks (RRs) of stomach cancer and the radiation-related excess relative risk (ERR) per gray were calculated by conditional logistic regression analysis." | 1.35 | Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy. ( Aleman, BM; Besseling, G; de Bruin, ML; de Wit, R; Gietema, JA; Hauptmann, M; Kerst, JM; Noordijk, EM; Ribot, JG; van 't Veer, MB; van den Belt-Dusebout, AW; van Leeuwen, FE, 2009) |
| "The treatment strategies of Hodgkin's lymphoma (HL) are different according to clinical stage and risk factors, yet the optimal treatment strategy remains unclear." | 1.34 | [Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases]. ( Hu, DS; Hu, S; Song, QB; Tan, WY; Wei, L; Zeng, FY; Zhou, LQ, 2007) |
| "Patients treated with radiotherapy for Hodgkin's disease have a considerable risk for a second cancer in long-term follow-up." | 1.30 | Second cancer among long-term survivors from Hodgkin's disease. ( Joensuu, H; Muhonen, T; Nyandoto, P, 1998) |
| "A past history of treated Hodgkin disease is a factor of risk for breast cancer and suggests the need for annual mammography screening 10 years after the end of treatment." | 1.29 | [Breast cancer after treatment of Hodgkin's disease]. ( Blanchot, J; Dugast, J; Grall, JY; Le Prise, E; Levêque, J; Meunier, B; Poulain, P, 1995) |
| "Two patients developed breast cancer 14 and 8 years after treatment of Hodgkin's disease." | 1.29 | Breast cancer developing after therapy for Hodgkin's disease. ( Cascinu, S; Catalano, G; Fedeli, A, 1993) |
| "We report about two cases of cancer of the testis occurring 2 and 7 years after Hodgkin's disease treated with combined chemotherapy and radiation therapy." | 1.28 | [Cancer of the testis after Hodgkin's disease. Apropos of 2 cases]. ( Averous, M; Chevallier, P; Grasset, D; Guiter, J; Iborra, F; Lavabre-Bertrand, T; Rebillard, X; Robert, M, 1992) |
| "2) Non-Hodgkin's lymphoma has not appeared in any of the patients in this series." | 1.28 | [Second neoplasms as a late complication of the treatment of Hodgkin's disease]. ( Alvarez, A; Colomé, JA; del Potro, E; Díaz Mediavilla, J; González, FA; Martínez, R; Morales, MD; Villegas, A, 1992) |
| "Thirty-four subsequent second malignant neoplasms were observed in 33 patients among those treated for Hodgkin's disease." | 1.27 | Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience. ( DeVita, VT; Glatstein, E; Kelley, PA; Kinsella, TJ; Makuch, RW; Tester, WJ; Waller, B, 1984) |
| "Patients who had a relapse of Hodgkin's disease did not have an increased incidence of second malignancy." | 1.27 | Second malignancy complicating Hodgkin's disease. ( Mercier, JP; Tawil, E, 1983) |
| "Two patients developed breast cancer after treatment of Hodgkin's disease." | 1.27 | Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease. ( Anderson, T; Cox, JD; Gillin, M; Greenberg, M; Janjan, NA; Schewe, K; Wilson, JF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (44.44) | 18.7374 |
| 1990's | 10 (27.78) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Eggermond, AM | 1 |
| Schaapveld, M | 1 |
| Janus, CP | 1 |
| de Boer, JP | 1 |
| Krol, AD | 1 |
| Zijlstra, JM | 1 |
| van der Maazen, RW | 1 |
| Kremer, LC | 1 |
| van Leerdam, ME | 1 |
| Louwman, MW | 1 |
| Visser, O | 1 |
| De Bruin, ML | 2 |
| Aleman, BM | 2 |
| van Leeuwen, FE | 2 |
| Almagro-Casado, E | 1 |
| Sánchez, A | 1 |
| Cantos, B | 1 |
| Salas, C | 1 |
| Pérez-Callejo, D | 1 |
| Provencio, M | 1 |
| Conway, JL | 1 |
| Connors, JM | 1 |
| Tyldesley, S | 1 |
| Savage, KJ | 1 |
| Campbell, BA | 1 |
| Zheng, YY | 1 |
| Hamm, J | 1 |
| Pickles, T | 1 |
| Mullah-Ali, A | 1 |
| Ramsay, JA | 1 |
| Bourgeois, JM | 1 |
| Hodson, I | 1 |
| Macdonald, P | 1 |
| Midia, M | 1 |
| Portwine, C | 1 |
| Aversa, SM | 1 |
| Trentin, C | 1 |
| Sorarů, M | 1 |
| Di Bona, E | 1 |
| Marino, D | 1 |
| Canova, F | 1 |
| Salvagno, L | 1 |
| Adami, F | 1 |
| van den Belt-Dusebout, AW | 1 |
| Besseling, G | 1 |
| Hauptmann, M | 1 |
| van 't Veer, MB | 1 |
| de Wit, R | 1 |
| Ribot, JG | 1 |
| Noordijk, EM | 1 |
| Kerst, JM | 1 |
| Gietema, JA | 1 |
| Haberer, S | 1 |
| Belin, L | 1 |
| Le Scodan, R | 1 |
| Kirova, YM | 1 |
| Savignoni, A | 1 |
| Stevens, D | 1 |
| Moisson, P | 1 |
| Decaudin, D | 1 |
| Pierga, JY | 1 |
| Reyal, F | 1 |
| Campana, F | 1 |
| Fourquet, A | 1 |
| Bollet, MA | 1 |
| DUHIG, JT | 1 |
| CONKLIN, JW | 1 |
| UPTON, AC | 1 |
| CHRISTENBERRY, KW | 1 |
| Morbidini-Gaffney, S | 1 |
| Alpert, TE | 1 |
| Hatoum, GF | 1 |
| Sagerman, RH | 1 |
| Mandal, S | 1 |
| Mandal, AK | 1 |
| Tan, WY | 1 |
| Hu, DS | 1 |
| Zeng, FY | 1 |
| Song, QB | 1 |
| Hu, S | 1 |
| Wei, L | 1 |
| Zhou, LQ | 1 |
| Jacquillat, C | 1 |
| Khayat, D | 1 |
| Desprez-Curely, JP | 1 |
| Weil, M | 1 |
| Brocheriou, C | 1 |
| Auclerc, G | 1 |
| Chamseddine, N | 1 |
| Bernard, J | 1 |
| Epstein, JH | 2 |
| Tester, WJ | 1 |
| Kinsella, TJ | 1 |
| Waller, B | 1 |
| Makuch, RW | 1 |
| Kelley, PA | 1 |
| Glatstein, E | 2 |
| DeVita, VT | 2 |
| Schmitt, K | 1 |
| Tulzer, W | 1 |
| Gassmann, W | 1 |
| Schmitz, N | 1 |
| Kayser, W | 1 |
| Löffler, H | 1 |
| Tawil, E | 1 |
| Mercier, JP | 1 |
| Hancock, RL | 1 |
| Gomez, GA | 1 |
| Aggarwal, KK | 1 |
| Han, T | 1 |
| Brusamolino, E | 1 |
| Lazzarino, M | 1 |
| Orlandi, E | 1 |
| Canevari, A | 1 |
| Morra, E | 1 |
| Castelli, G | 1 |
| Alessandrino, EP | 1 |
| Pagnucco, G | 1 |
| Astori, C | 1 |
| Livraghi, A | 1 |
| Licata, AG | 1 |
| Wilson, LD | 1 |
| Braverman, IM | 1 |
| Feldman, AM | 1 |
| Kacinski, BM | 1 |
| Levêque, J | 1 |
| Meunier, B | 1 |
| Poulain, P | 1 |
| Blanchot, J | 1 |
| Dugast, J | 1 |
| Le Prise, E | 1 |
| Grall, JY | 1 |
| Anderson, JR | 1 |
| Vose, J | 1 |
| Kessinger, A | 1 |
| Cascinu, S | 1 |
| Fedeli, A | 1 |
| Catalano, G | 1 |
| Falchero, L | 1 |
| Coiffier, B | 1 |
| Guibert, B | 1 |
| Souquet, PJ | 1 |
| Isaac Pinet, S | 1 |
| Trillet-Lenoir, V | 1 |
| Nyandoto, P | 1 |
| Muhonen, T | 1 |
| Joensuu, H | 1 |
| Aisenberg, AC | 1 |
| Robert, M | 1 |
| Averous, M | 1 |
| Lavabre-Bertrand, T | 1 |
| Iborra, F | 1 |
| Chevallier, P | 1 |
| Rebillard, X | 1 |
| Guiter, J | 1 |
| Grasset, D | 1 |
| Morales, MD | 1 |
| González, FA | 1 |
| Villegas, A | 1 |
| del Potro, E | 1 |
| Díaz Mediavilla, J | 1 |
| Martínez, R | 1 |
| Alvarez, A | 1 |
| Colomé, JA | 1 |
| Young, RC | 1 |
| Longo, DL | 1 |
| Ihde, DC | 1 |
| Jaffe, ES | 1 |
| Jenkin, D | 1 |
| Doyle, J | 1 |
| Tokuoka, S | 1 |
| Inai, K | 1 |
| Janjan, NA | 1 |
| Wilson, JF | 1 |
| Gillin, M | 1 |
| Anderson, T | 1 |
| Greenberg, M | 1 |
| Schewe, K | 1 |
| Cox, JD | 1 |
| Perri, RT | 1 |
| Allen, JI | 1 |
| Oken, MM | 1 |
| Limas, C | 1 |
| Kay, NE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Late Treatment Effects in Long-Term Survivors of Hodgkin's Disease Previously Treated at NIH: A Multi-Institutional Trial[NCT00924131] | 157 participants (Anticipated) | Observational | 2009-04-17 | Completed | |||
| A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodg[NCT00479167] | Phase 2 | 1 participants (Actual) | Interventional | 2007-05-31 | Terminated (stopped due to Lack of accrual and interest in study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for mechlorethamine and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 18; Chromosomes, Human, X; | 2008 |
Non-Hodgkin's lymphoma occurring after Hodgkin's disease. Four new cases and a review of the literature.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; | 1984 |
Malignant melanoma and other second cutaneous malignancies in cutaneous T-cell lymphoma. The influence of additional therapy after total skin electron beam radiation.
Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Electrons; Female; Humans; Lymphoma, T | 1995 |
[Malignant mesothelioma of the pleura following radiotherapy of Hodgkin disease].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Hodgkin Disease; Humans; | 1996 |
Problems in Hodgkin's disease management.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant | 1999 |
[Lung cancer and related environmental factors].
Topics: Asbestos; Bronchi; Epithelium; Humans; Lung Neoplasms; Mechlorethamine; Neoplasms, Radiation-Induced | 1988 |
2 trials available for mechlorethamine and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Post-therapeutic acute malignant myeloproliferative syndrome and acute nonlymphocytic leukemia in non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Carmustine; Cyclophosphamide; Drug Administration Schedule; Drug | 1982 |
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub | 1988 |
28 other studies available for mechlorethamine and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colon; Colo | 2017 |
Lung cancer and other second neoplasms after treatment of Hodgkin lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Dox | 2016 |
Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma.
Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 2017 |
Acute promyelocytic leukemia after Stanford V plus radiotherapy for advanced Hodgkin lymphoma.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin | 2009 |
Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cohort Studies; Combine | 2009 |
Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms | 2012 |
TUMOR INCIDENCE IN A-STRAIN MICE.
Topics: Cyclophosphamide; Incidence; Leukemia; Leukemia, Radiation-Induced; Lung Neoplasms; Mechlorethamine; | 1965 |
FURTHER OBSERVATIONS ON LATE SOMATIC EFFECTS OF RADIOMIMETIC CHEMICALS AND X-RAYS IN MICE.
Topics: Aging; Busulfan; Cataract; Female; Humans; Leukemia; Leukemia, Myeloid; Longevity; Lung Neoplasms; L | 1965 |
Benign pleural schwannoma secondary to radiotherapy for Hodgkin disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Combin | 2005 |
Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adju | 2007 |
[Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co | 2007 |
Nitrogen mustard (mechlorethamine) and UVB photocarcinogenesis: a dose response effect.
Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Mechlorethamine; Mice; Mice, Ha | 1984 |
Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Combine | 1984 |
[Second tumor following Hodgkin's disease].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child, Presc | 1984 |
Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Combined Modality Therapy; Drug Resistanc | 1984 |
Effects of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis in hairless mouse skin.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Mechlorethamine; Mice; Mice, Hairless; Neoplasm | 1984 |
Second malignancy complicating Hodgkin's disease.
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cycloph | 1983 |
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins. VI. Radiation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Chromatin; Dose-Response Relationship, Radiat | 1980 |
Early-stage Hodgkin's disease: long-term results with radiotherapy alone or combined radiotherapy and chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Combin | 1994 |
[Breast cancer after treatment of Hodgkin's disease].
Topics: Adenocarcinoma; Adult; Aftercare; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 1995 |
Myelodysplastic syndrome after autologous transplant for lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Hematopoietic Stem Cell Transplantation; Hodgkin Dis | 1994 |
Breast cancer developing after therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intr | 1993 |
Second cancer among long-term survivors from Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleom | 1998 |
[Cancer of the testis after Hodgkin's disease. Apropos of 2 cases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Dysgermi | 1992 |
[Second neoplasms as a late complication of the treatment of Hodgkin's disease].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinom | 1992 |
Pediatric Hodgkin's disease. Later results and toxicity--the Toronto experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Follow | 1989 |
Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Hodgkin | 1988 |
Simultaneous presentation of relapsing Hodgkin's disease and treatment-related non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Hodgkin Disease; Humans; | 1985 |