mechlorethamine has been researched along with Body Weight in 29 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These outcomes will add to our understanding of the toxic effects of topical vesicant exposure, which might be helpful towards developing effective countermeasures against injuries from acute topical exposures." | 1.42 | Topical nitrogen mustard exposure causes systemic toxic effects in mice. ( Agarwal, C; Agarwal, R; Dhar, D; Goswami, DG; Inturi, S; Jain, AK; Kant, R; Kumar, D; Orlicky, DJ; Rancourt, RC; Tewari-Singh, N; White, CW, 2015) |
| " Single dose of 1 LD50 of nitrogen mustards and sulphur mustard was administered percutaneously and various oxidative stress parameters were also evaluated." | 1.35 | Comparison of toxicity of selected mustard agents by percutaneous and subcutaneous routes. ( Ganesan, K; Sharma, M; Vijayaraghavan, R, 2008) |
| " Using this assay in the present study, dose-response relationships of cytotoxicity, PFC response and histology in the spleen were evaluated in rats receiving alkylating agents." | 1.29 | Dose-response relationships of cytotoxicity, PFC response and histology in the spleen in rats treated with alkylating agents. ( Doi, T; Nagai, H; Suzuki, T; Tsukuda, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (68.97) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goswami, DG | 1 |
| Kumar, D | 1 |
| Tewari-Singh, N | 1 |
| Orlicky, DJ | 1 |
| Jain, AK | 1 |
| Kant, R | 1 |
| Rancourt, RC | 1 |
| Dhar, D | 1 |
| Inturi, S | 1 |
| Agarwal, C | 1 |
| White, CW | 1 |
| Agarwal, R | 1 |
| Sharma, M | 3 |
| Vijayaraghavan, R | 4 |
| Ganesan, K | 1 |
| Gautam, A | 1 |
| Agrawal, OP | 1 |
| INCH, WR | 1 |
| McCREDIE, JA | 1 |
| HUSVETI, S | 1 |
| BESZNYAK, I | 1 |
| KUDASZ, J | 1 |
| SYRKIN, AB | 1 |
| CHUMAKOV, VM | 1 |
| FIELD, JB | 1 |
| MIRELES, A | 1 |
| DOLENDO, EC | 1 |
| ERSHOFF, BH | 1 |
| ITO, T | 1 |
| Vincent, PC | 2 |
| Reeve, TS | 2 |
| Brittle, N | 2 |
| Nicholls, A | 2 |
| Richards, M | 1 |
| Bhattacharya, S | 1 |
| Ganguly, C | 1 |
| Sanyal, U | 1 |
| Das, S | 1 |
| Doi, T | 1 |
| Nagai, H | 1 |
| Tsukuda, R | 1 |
| Suzuki, T | 1 |
| Kumar, P | 1 |
| Joshi, U | 1 |
| Raza, SK | 1 |
| Lakshmana Rao, PV | 1 |
| Malhotra, RC | 1 |
| Jaiswal, DK | 1 |
| Avilés, A | 2 |
| Neri, N | 1 |
| Cooke, RA | 1 |
| Nikles, A | 1 |
| Roeser, HP | 1 |
| Takamizawa, A | 1 |
| Matsumoto, S | 1 |
| Iwata, T | 1 |
| Tochino, Y | 1 |
| Katagiri, K | 1 |
| Yamaguchi, K | 1 |
| Díaz-Maqueo, JC | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| García, EL | 1 |
| Takeda, M | 1 |
| Hosaka, M | 1 |
| Kitajima, N | 1 |
| Noguchi, K | 1 |
| Fujii, H | 1 |
| Oshima, H | 1 |
| Harada, M | 1 |
| Druker, BJ | 1 |
| Rosenthal, DS | 1 |
| Canellos, GP | 1 |
| Vojvodić, V | 1 |
| Milosavljević, Z | 1 |
| Bosković, B | 1 |
| Bojanić, N | 1 |
| Lokich, JJ | 1 |
| Galvanek, EG | 1 |
| Moloney, WC | 1 |
| McDowell, AA | 1 |
| Chang-Yit, RH | 1 |
| Condell, Y | 1 |
| Bailey, EM | 1 |
| Picken, JC | 1 |
| Elson, LA | 1 |
| Kito, T | 1 |
| Murakami, K | 2 |
| Ueda, Y | 2 |
| Tsunoda, T | 2 |
| Mikami, M | 2 |
| Yamamoto, M | 2 |
| Host, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 other studies available for mechlorethamine and Body Weight
| Article | Year |
|---|---|
Topical nitrogen mustard exposure causes systemic toxic effects in mice.
Topics: Administration, Cutaneous; Animals; Apoptosis; Body Weight; Chemical Warfare Agents; Hematopoietic S | 2015 |
Comparison of toxicity of selected mustard agents by percutaneous and subcutaneous routes.
Topics: Administration, Cutaneous; Animals; Body Weight; Female; Injections, Subcutaneous; Mechlorethamine; | 2008 |
DRDE-07 and its analogues as promising cytoprotectants to nitrogen mustard (HN-2)--an alkylating anticancer and chemical warfare agent.
Topics: Amifostine; Animals; Antidotes; Antineoplastic Agents, Alkylating; Body Weight; Chemical Warfare Age | 2009 |
Comparative toxic effect of nitrogen mustards (HN-1, HN-2, and HN-3) and sulfur mustard on hematological and biochemical variables and their protection by DRDE-07 and its analogues.
Topics: Alkaline Phosphatase; Amifostine; Animals; Body Weight; Female; Lethal Dose 50; Leukocyte Count; Mec | 2010 |
Effect of aging aqueous nitrogen mustard on white blood cell count, body weight, and Walker 256 tumor in the rat.
Topics: Animals; Body Weight; Carcinoma; Carcinoma 256, Walker; Leukocyte Count; Mechlorethamine; Rats | 1963 |
[EXPERIMENTAL REGIONAL PERFUSION OF THE EXTREMITIES WITH CYTOSTATICS].
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Body Weight; Chemotherapy, Cancer, Regional Perfus | 1963 |
INFLUENCE OF SOME ANTITUMOR DRUGS ON BODY AND ORGANS GROWTH IN RATS.
Topics: Adrenal Glands; Antineoplastic Agents; Body Weight; Bone and Bones; Brain; Chlorambucil; Diaphragm; | 1964 |
REVERSAL OF NITROGEN MUSTARD INTOXICATION BY ANTI-HISTAMINES.
Topics: Anti-Allergic Agents; Body Weight; Body Weights and Measures; Dimethindene; Histamine; Histamine H1 | 1964 |
[HEMATOLOGICAL AND HISTOLOGICAL STUDIES IN THE OFFSPRINGS OF WISTAR STRAIN ALBINO RATS TREATED WITH ANTICANCER DRUGS OF X-RAY IRRADIATION. I. HEMATOLOGICAL AND HISTOLOGICAL OBSERVATIONS ON WISTAR STRAIN RATS ADMINISTERED WITH NITROGEN MUSTARD-N-OXIDE].
Topics: Animals; Antineoplastic Agents; Blood Cells; Body Weight; Body Weights and Measures; Mechlorethamine | 1965 |
The effect of cytotoxic drugs on serum albumin in the rat.
Topics: Animals; Blood Protein Disorders; Blood Protein Electrophoresis; Body Weight; Cyclophosphamide; Mala | 1967 |
Evaluation of phthalmustine, a new anticancer compound. I. Effect on Dalton's ascitic lymphoma in mice.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Body Weight; DNA, Neoplasm; Drug Evaluation, Precl | 1994 |
Dose-response relationships of cytotoxicity, PFC response and histology in the spleen in rats treated with alkylating agents.
Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Cell Count; Cell Survival; Chlorambucil; Cy | 1996 |
Prophylactic efficacy of amifostine and its analogues against sulphur mustard toxicity.
Topics: Administration, Oral; Amifostine; Animals; Body Weight; Dermatologic Agents; DNA Fragmentation; Fema | 2001 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
A comparison of the antifertility effects of alkylating agents and vinca alkaloids in male rats.
Topics: Alkylating Agents; Animals; Blood; Body Weight; Cyclophosphamide; Fertility; Male; Mechlorethamine; | 1978 |
Studies on cyclophosphamide metabolites and their related compounds. 2. Preparation of an active species of cyclophosphamide and related compounds.
Topics: Acetals; Animals; Body Weight; Cyclophosphamide; HeLa Cells; Lethal Dose 50; Leukemia L1210; Magneti | 1975 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
[Effect of anticancer agents on rat prostate. Evaluation of organ weight, histological finding and 5 alpha-reductase activities].
Topics: Animals; Antineoplastic Agents; Bleomycin; Body Weight; Cholestenone 5 alpha-Reductase; Cisplatin; C | 1985 |
Chlorambucil, vinblastine, procarbazine, and prednisone. An effective but less toxic regimen than MOPP for advanced-stage Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chlorambucil; Female; Hodg | 1989 |
The protective effect of different drugs in rats poisoned by sulfur and nitrogen mustards.
Topics: Animals; Antidotes; Body Weight; Chinchilla; Cholinesterases; Female; Lethal Dose 50; Male; Mechlore | 1985 |
Nephrosis of Hodgkin disease. An immune complex-induced lesion.
Topics: Antigen-Antibody Complex; Basement Membrane; Biopsy; Blood Urea Nitrogen; Body Weight; Capillaries; | 1973 |
Chronic effects of a single nitrogen mustard injection on the activity response of albino rats.
Topics: Animals; Blood Cell Count; Body Weight; Dose-Response Relationship, Drug; Injections, Intramuscular; | 1973 |
Effects of two alkylating agents in calves.
Topics: Alkylating Agents; Animals; Biological Assay; Blood Cells; Blood Proteins; Body Weight; Cattle; Catt | 1971 |
The effect of large doses of cytotoxic drugs on the blood volume of the rat.
Topics: Anemia, Hemolytic; Animals; Blood Volume; Body Weight; Cyclophosphamide; Erythrocytes; Mechlorethami | 1966 |
Growth inhibitory and haematological effects of alkylating agents and attempts at their modification to give greater selectivity of anti-tumour action.
Topics: Alkylating Agents; Animals; Body Weight; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Chlor | 1968 |
Effect of oxygen at high pressure on the growth of Ehrlich ascites tumor; especially on the combined therapy with methyl-bis-(2-chloroethyl)amine N-oxide hydrochloride.
Topics: Animals; Ascitic Fluid; Body Weight; Carcinoma, Ehrlich Tumor; Female; Lung; Mechlorethamine; Mice; | 1968 |
[Addenda to the study of the effect of carcinostatic drugs on human beings. I. Death rate of young and adult albino rats after administration of sublethal doses, equally divided per body weight].
Topics: Age Factors; Animals; Body Weight; Mechlorethamine; Methotrexate; Mitomycins; Rats | 1968 |
[Addenda to the study of the effect of carcinostatic drugs on human beings. II. Variations in peripheral blood in young and adult albino rats after administration of sublethal doses, equally divided per body weight].
Topics: Aging; Animals; Blood Cell Count; Blood Cells; Body Weight; Hemoglobins; Mechlorethamine; Methotrexa | 1968 |
Comparative effects of cyclophosphamide, nitrogen mustard, and total-body irradiation on survival and on white blood cells in rats.
Topics: Animals; Body Weight; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Female; Leukocyte Count; Leu | 1966 |