mechlorethamine has been researched along with Benign Neoplasms, Brain in 40 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Excerpt | Relevance | Reference |
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"Previous investigators have reported responses in 52% of patients treated with mechlorethamine (nitrogen mustard), vincristine, and procarbazine (MOP) for recurrent glioma." | 9.08 | Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results. ( Buckner, JC; Burch, PA; Dinapoli, RP; Galanis, E; Mailliard, JA; Morton, RF; Novotny, PJ; Rowland, KM; Schaefer, PL; Scheithauer, BW; Vukov, AM, 1998) |
"The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma." | 8.78 | Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992) |
"Biopsy samples and cultured cells derived from them were obtained from 39 patients with malignant glioma and were analyzed for 1) glutathione (GSH) content; 2) sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or nitrogen mustard (HN2) treatment and 3) the effect of buthionine sulfoximine (BSO) treatment on BCNU and/or HN2 cytotoxicity." | 7.68 | Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells. ( Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK, 1991) |
"Previous investigators have reported responses in 52% of patients treated with mechlorethamine (nitrogen mustard), vincristine, and procarbazine (MOP) for recurrent glioma." | 5.08 | Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results. ( Buckner, JC; Burch, PA; Dinapoli, RP; Galanis, E; Mailliard, JA; Morton, RF; Novotny, PJ; Rowland, KM; Schaefer, PL; Scheithauer, BW; Vukov, AM, 1998) |
"The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma." | 4.78 | Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992) |
"Estramustine phosphate (EMP) is an anti-microtubule agent that induces apoptosis of glioma cells." | 3.71 | Induction of apoptosis by estramustine phosphate mediated by phosphorylation of bcl-2. ( Noha, M; Sugisaki, Y; Takahashi, H; Teramoto, A; Watanabe, K; Yoshida, D, 2001) |
"Between 1978 and 1988, 20 children with medulloblastoma (MB) of the brain were treated postoperatively with MOPP (nitrogen mustard, vincristine, prednisone, and procarbazine)." | 3.68 | Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. ( Hayani, A; Mahoney, DH; Taylor, LD, 1992) |
"Biopsy samples and cultured cells derived from them were obtained from 39 patients with malignant glioma and were analyzed for 1) glutathione (GSH) content; 2) sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or nitrogen mustard (HN2) treatment and 3) the effect of buthionine sulfoximine (BSO) treatment on BCNU and/or HN2 cytotoxicity." | 3.68 | Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells. ( Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK, 1991) |
"Thirteen patients with advanced (Stage III) malignant melanoma have been treated with high-dose chemotherapy (nitrogen mustard or a combination of BCNU and melphalan) combined with autologous, nonfrozen, bone marrow transplantation." | 3.66 | Treatment of advanced malignant melanoma with high-dose chemotherapy and autologous bone marrow transplantation. Preliminary results--Phase I study. ( Dantas, ME; Glode, LM; Koeppler, H; Morton, N; Robinson, WA; Sutherland, J; Thomas, MR, 1982) |
"Infants and young children who have brain tumors have a poor rate of survival and high treatment associated morbidity." | 1.30 | MOPP chemotherapy without irradiation as primary postsurgical therapy for brain tumors in infants and young children. ( Ater, JL; Bruner, J; Copeland, DR; Moore, B; van Eys, J; Woo, SY, 1997) |
"7 of 8 with brain metastases treated by the same modality gave complete remission." | 1.27 | [Combination therapy of advanced choriocarcinoma--an analysis of 60 patients]. ( Cai, SM; Ding, YQ; Wang, RY, 1986) |
"Central nervous system involvement with Hodgkin's disease is extremely rare and is almost always a late complication in patients who have widely disseminated disease in the usual nodal sites." | 1.27 | Hodgkin's disease presenting with isolated craniospinal involvement. ( Bender, BL; Mayernik, DG, 1986) |
"Five children with brain tumors, who had had no prior chemotherapy, were treated with combination chemotherapy including nitrogen mustard, vincristine sulfate, procarbazine, prednisolone (MOPP) and intrathecal methotrexate." | 1.27 | [Combination chemotherapy with MOPP and intrathecal methotrexate in children with brain tumors]. ( Akita, H; Hashimoto, T; Hirose, M; Matsumoto, K; Miki, Y; Miyao, M; Ninomiya, T; Saijo, T; Sato, J, 1986) |
"Intracranial hodgkin's disease, an extremely uncommon finding, is reported in a 21-year-old man." | 1.27 | Hodgkin's disease, intracranial involvement. Report of a case and review of the literature. ( Enriquez, R; Papac, R; Vera, R, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 34 (85.00) | 18.7374 |
1990's | 5 (12.50) | 18.2507 |
2000's | 1 (2.50) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
SOKOL, S | 1 |
ANDERSON, B | 2 |
HATIBOGLU, I | 1 |
OWENS, G | 2 |
WESTBURY, G | 1 |
JAVID, R | 1 |
TALLON, M | 1 |
STEPANIAN, G | 1 |
BELMUSTO, L | 1 |
GONDOS, B | 1 |
REINGOLD, IM | 1 |
RATTIGAN, JP | 1 |
MICHELSON, AL | 1 |
POMERANTZ, AZ | 1 |
FRENCH, JD | 1 |
WEST, PM | 1 |
VON AMERONGEN, FK | 1 |
MAGOUN, HW | 1 |
Moser, K | 1 |
Pohl, A | 1 |
Cangir, A | 4 |
Ragab, AH | 1 |
Steuber, P | 1 |
Land, VJ | 1 |
Berry, DH | 2 |
Krischer, JP | 1 |
Schmitt, K | 1 |
Tulzer, W | 1 |
Thomas, MR | 1 |
Robinson, WA | 1 |
Glode, LM | 1 |
Dantas, ME | 1 |
Koeppler, H | 1 |
Morton, N | 1 |
Sutherland, J | 1 |
Shafer, RH | 1 |
Chase, ES | 1 |
Ater, JL | 1 |
van Eys, J | 5 |
Woo, SY | 1 |
Moore, B | 1 |
Copeland, DR | 1 |
Bruner, J | 1 |
Galanis, E | 1 |
Buckner, JC | 1 |
Burch, PA | 1 |
Schaefer, PL | 1 |
Dinapoli, RP | 1 |
Novotny, PJ | 1 |
Scheithauer, BW | 1 |
Rowland, KM | 1 |
Vukov, AM | 1 |
Mailliard, JA | 1 |
Morton, RF | 1 |
Yoshida, D | 1 |
Noha, M | 1 |
Watanabe, K | 1 |
Takahashi, H | 1 |
Sugisaki, Y | 1 |
Teramoto, A | 1 |
Holoye, PY | 1 |
Mensi, F | 1 |
Bombara, R | 1 |
Massari, A | 1 |
Sala, F | 1 |
Visca, U | 1 |
Hvizdala, E | 1 |
Morgan, SK | 1 |
Hayani, A | 1 |
Mahoney, DH | 1 |
Taylor, LD | 1 |
Coyle, T | 1 |
Bushunow, P | 1 |
Winfield, J | 1 |
Wright, J | 1 |
Graziano, S | 1 |
Allalunis-Turner, MJ | 1 |
Day, RS | 1 |
McKean, JD | 1 |
Petruk, KC | 1 |
Allen, PB | 1 |
Aronyk, KE | 1 |
Weir, BK | 1 |
Huyser-Wierenga, D | 1 |
Fulton, DS | 1 |
Urtasun, RC | 1 |
Cai, SM | 1 |
Wang, RY | 1 |
Ding, YQ | 1 |
Evans, CG | 1 |
Bodell, WJ | 2 |
Tokuda, K | 1 |
Doane-Setzer, P | 1 |
Smith, MT | 1 |
Takaue, Y | 1 |
Sullivan, MP | 1 |
Ramirez, I | 1 |
Cleary, KR | 1 |
Stokes, DC | 1 |
Shenep, JL | 1 |
Horowitz, ME | 1 |
Hughes, WT | 1 |
Baram, TZ | 1 |
Bruner, JM | 1 |
Martinez-Prieto, J | 1 |
Aida, T | 1 |
Gurney, HP | 1 |
Phadke, K | 1 |
Jostes, R | 1 |
Deen, DF | 1 |
Bender, BL | 1 |
Mayernik, DG | 1 |
Sato, J | 1 |
Ninomiya, T | 1 |
Saijo, T | 1 |
Akita, H | 1 |
Miki, Y | 1 |
Hirose, M | 1 |
Hashimoto, T | 1 |
Miyao, M | 1 |
Matsumoto, K | 1 |
Vera, R | 1 |
Enriquez, R | 1 |
Papac, R | 1 |
Coody, D | 1 |
Smith, B | 1 |
Wilson, CB | 1 |
Hoshino, T | 1 |
Miller, DR | 1 |
Sonley, M | 1 |
Karon, M | 1 |
Breslow, N | 1 |
Hammond, D | 1 |
Mahaley, MS | 2 |
Woodhall, B | 2 |
Gaelen, LH | 1 |
Levitan, S | 1 |
Sanders, AP | 1 |
2 reviews available for mechlorethamine and Benign Neoplasms, Brain
Article | Year |
---|---|
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Hypersensit | 1992 |
1 trial available for mechlorethamine and Benign Neoplasms, Brain
Article | Year |
---|---|
Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Female; Glioma; | 1998 |
37 other studies available for mechlorethamine and Benign Neoplasms, Brain
Article | Year |
---|---|
[Treatment of cerebral metastases with oxidized nitrogen mustards].
Topics: Brain; Brain Neoplasms; Mechlorethamine; Nitrogen Mustard Compounds | 1956 |
Necrotizing uveitis incident to perfusion of intractraial malignancies with nitrogen mustard or related compounds.
Topics: Brain Neoplasms; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Perfusion; Uveitis | 1960 |
Results of intermittent, prolonged infusion of nitrogen mustard into the carotid artery in twelve patients with cerebral gliomas.
Topics: Brain Neoplasms; Carotid Arteries; Glioma; Humans; Mechlorethamine; Nitrogen Mustard Compounds | 1961 |
CONTINUOUS INTRA-ARTERIAL INFUSION AND INTERMITTENT INTRA-ARTERIAL INJECTION.
Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Ethoglucid; Head a | 1963 |
ARTERIAL INFUSION CHEMOTHERAPY OF PRIMARY GLIOMAS.
Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Glioma; Mechloreth | 1963 |
MEDIASTINAL GANGLIONEUROBLASTOMA METASTASIZING TO SCALENE LYMPH NODES IN AN ADULT. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Autopsy; Black People; Brain Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Diagnosis, Differential; | 1964 |
Bronchogenic carcinoma with intracranial metastasis (symptomatic improvement following nitrogen mustard therapy.
Topics: Brain; Brain Neoplasms; Carcinoma, Bronchogenic; Lung Neoplasms; Mechlorethamine; Nitrogen Mustard C | 1952 |
Effects of intracarotid administration of nitrogen mustard on normal brain and brain tumors.
Topics: Brain; Brain Neoplasms; Mechlorethamine; Nitrogen Mustard Compounds; Pharmaceutical Preparations | 1952 |
Combination chemotherapy with vincristine (NSC-67574), procarbazine (NSC-77213), prednisone (NSC-10023) with or without nitrogen mustard (NSC-762)(MOPP vs OPP) in children with recurrent brain tumors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Follow-Up | 1984 |
[Second tumor following Hodgkin's disease].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child, Presc | 1984 |
Treatment of advanced malignant melanoma with high-dose chemotherapy and autologous bone marrow transplantation. Preliminary results--Phase I study.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Carmustine; | 1982 |
DNA damage in rat 9L cells treated with nitrogen mustard and 1,3-bis(2-chloroethyl)-1-nitrosourea assayed by viscoelastometry and S1 nuclease.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Cross-Linking Reagents; Deoxyribonucleases; DNA, Ne | 1980 |
MOPP chemotherapy without irradiation as primary postsurgical therapy for brain tumors in infants and young children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebellar Neoplasms; Chemotherapy, | 1997 |
Induction of apoptosis by estramustine phosphate mediated by phosphorylation of bcl-2.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Astrocytes; Brain Neoplasms; Ele | 2001 |
Management of small-cell bronchogenic carcinoma.
Topics: Altretamine; Antibiotics, Antineoplastic; Brain Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide | 1978 |
[The chordoma. Description of 2 clinical cases and results of oncolytic chemotherapy].
Topics: Adult; Aged; Brain Neoplasms; Chordoma; Coccyx; Cyclophosphamide; Humans; Male; Mechlorethamine; Neo | 1979 |
Combination chemotherapy with MOPP in children with recurrent brain tumors.
Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Drug Therapy, Combinati | 1978 |
Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool | 1992 |
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; C | 1991 |
[Combination therapy of advanced choriocarcinoma--an analysis of 60 patients].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Combined Modality | 1986 |
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatograp | 1987 |
Second malignant neoplasm in treated Hodgkin's disease. Report of a patient and scope of the problem.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; G | 1986 |
Presentation of Pneumocystis carinii pneumonia as unilateral hyperlucent lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child, Preschool; Huma | 1988 |
Salvage chemotherapy for recurrent primary brain tumors in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Chi | 1988 |
[Anticancer drug induced sister chromatid exchange and correlation to cell survival in human brain tumor cells].
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line; Cell Survival; Cisplatin; Glioma; Hum | 1987 |
Hodgkin's disease presenting with central nervous system involvement.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Hodgkin Disease; Humans; Mal | 1987 |
Double elution analysis of cross-link formation and repair in cycling and noncycling 9L spheroid cells.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cross-Linking Reagents; Culture Techniques; DNA Repair; DNA, N | 1986 |
Hodgkin's disease presenting with isolated craniospinal involvement.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; D | 1986 |
[Combination chemotherapy with MOPP and intrathecal methotrexate in children with brain tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Choroid Pl | 1986 |
Hodgkin's disease, intracranial involvement. Report of a case and review of the literature.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Hodgkin Disease; Humans; Mal | 1985 |
MOPP regimen as primary chemotherapy for brain tumors in infants.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; | 1985 |
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; | 1969 |
Additive therapy in the maintenance of remission in acute lymphoblastic leukemia of childhood: the effect of the initial leukocyte count.
Topics: Adolescent; Age Factors; Blood; Brain Neoplasms; Child; Child, Preschool; Dactinomycin; Digestive Sy | 1974 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci | 1967 |
Solitary intracranial metastasis by Hodgkin's disease.
Topics: Adult; Brain Neoplasms; Cerebral Angiography; Cerebral Ventriculography; Dura Mater; Female; Hodgkin | 1967 |
Brain perfusion for tumour--the effect of nitrogen mustard on brain adenosine triphosphate.
Topics: Acid Phosphatase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Neoplasms; Carbon I | 1968 |
The in vitro respiration of normal brain and brain tumors.
Topics: Brain; Brain Neoplasms; Cyclophosphamide; Humans; In Vitro Techniques; Mechlorethamine; Methotrexate | 1966 |