Page last updated: 2024-10-30

mechlorethamine and Anemia

mechlorethamine has been researched along with Anemia in 19 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.

Research Excerpts

ExcerptRelevanceReference
" This side effect could be explained by a cycling of the hematopoietic stem-cells and call to some caution when androgens are used during cancer chemotherapy."2.64[Increased hematological toxicity of antineoplastic drugs with simultaneous androgenotherapy (author's transl)]. ( Barthélémy, M; Bilski-Pasquier, G; Blanc, CM; Bouchard, M; Bousser, J; Zittoun, R, 1977)
"In three patients with advanced Hodgkin's disease treated with combination chemotherapy (MOPP) incorporating vincristine, and receiving at the same time a fixed daily dose of 8000 U of rHu-EPO subcutaneously for 10 to 15 days because of myelosuppressive anemia, myeloaspirates were performed one week before and 24 hours after the administration of vincristine."1.28Selective metaphasic arrest of erythroblasts by vincristine in patients receiving high doses of recombinant human erythropoietin for myelosuppressive anemia. ( Marmont, AM, 1992)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199018 (94.74)18.7374
1990's1 (5.26)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BROMBERG-SZNEK, S1
ERSLEV, AJ1
LAVIETES, PH1
FROMOWICZ, KK1
PALESTER, M1
HEYL, T1
MATSUOKA, M1
MAUER, AM1
KRILL, CE1
KURZ, GH1
BURNINGHAM, RA1
RESTREPO, A1
PUGH, RP1
BROWN, EB1
SCHLOSSMAN, SF1
KHURI, PD1
LESSNER, HE1
HARRINGTON, WJ1
DAMESHEK, W1
THOMAS, ED1
FLIEDNER, TM1
THOMAS, D1
CRONKITE, EP1
GONZAGA, E2
ROMEO, G1
Shamberger, RC1
Devereux, DF1
Brennan, MF1
Willemze, R1
Walker, RI1
Herion, JC1
Palmer, JG1
Zittoun, R1
Barthélémy, M1
Bouchard, M1
Blanc, CM1
Bousser, J1
Bilski-Pasquier, G1
Marmont, AM1
Fairley, GH1
Greenberg, LH1
Wong, S1
Richardson, AP1
Dollinger, MR1

Reviews

2 reviews available for mechlorethamine and Anemia

ArticleYear
RECENT STUDIES IN AUTOIMMUNITY.
    Acta haematologica, 1964, Volume: 31

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anemia; Anemia, Hemolytic; Antibody Formation;

1964
The effect of chemotherapeutic agents on wound healing.
    International advances in surgical oncology, 1981, Volume: 4

    Topics: Adrenal Cortex Hormones; Anemia; Animals; Antineoplastic Agents; Azathioprine; Collagen; Cyclophosph

1981

Trials

1 trial available for mechlorethamine and Anemia

ArticleYear
[Increased hematological toxicity of antineoplastic drugs with simultaneous androgenotherapy (author's transl)].
    La Nouvelle presse medicale, 1977, Sep-17, Volume: 6, Issue:30

    Topics: Androgens; Anemia; Antineoplastic Agents; Drug Therapy, Combination; Humans; Lymphoma; Mechlorethami

1977

Other Studies

16 other studies available for mechlorethamine and Anemia

ArticleYear
[Therapeutic action of small doses of nitrogen mustard in hemolytic anemia].
    Polski tygodnik lekarski, 1952, Oct-20, Volume: 7, Issue:42

    Topics: Anemia; Anemia, Hemolytic; Mechlorethamine; Nitrogen Mustard Compounds; Tracheophyta

1952
Observations on the nature of the erythropoietic serum factor.
    Blood, 1954, Volume: 9, Issue:11

    Topics: Anemia; Erythrocytes; Mechlorethamine; Nitrogen Mustard Compounds

1954
[Result of the treatment of acquired hemolytic anemia with nitrogen mustard].
    Polskie Archiwum Medycyny Wewnetrznej, 1956, Volume: 26, Issue:11

    Topics: Anemia; Anemia, Hemolytic; Humans; Mechlorethamine; Nitrogen Mustard Compounds

1956
[Bone-marrow transplantation in patients with bone-marrow depression. Aplastic anemia after nitrogen mustard therapy].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1961, Jul-22, Volume: 35

    Topics: Anemia; Anemia, Aplastic; Bone Marrow; Bone Marrow Transplantation; Depression; Humans; Mechloretham

1961
[IMPROVEMENT AND EXACERBATION IN LEUKEMIA].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Aminocaproates; Aminocaproic Acid; Anemia; Antineoplastic Agents; Blood Transfusion; Busulfan; Centr

1963
A STUDY OF THE MECHANISMS OF GRANULOCYTOPENIA.
    Annals of the New York Academy of Sciences, 1964, Feb-28, Volume: 113

    Topics: Agranulocytosis; Anemia; Anemia, Macrocytic; Carcinoma; Carcinoma, Bronchogenic; Child; Hodgkin Dise

1964
RETINOPATHY OF OBSCURE (TOXIC?) ORIGIN IN HODGKIN'S DISEASE.
    American journal of ophthalmology, 1964, Volume: 57

    Topics: Anemia; Chloramphenicol; Chlorpromazine; Eye; Glutethimide; Herpes Zoster; Herpes Zoster Ophthalmicu

1964
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
    The New England journal of medicine, 1964, May-28, Volume: 270

    Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia;

1964
THE PROBLEM OF THE STEM CELL: OBSERVATIONS IN DOGS FOLLOWING NITROGEN MUSTARD.
    The Journal of laboratory and clinical medicine, 1965, Volume: 65

    Topics: Anemia; Anemia, Aplastic; Autoradiography; Bone Marrow Cells; Bone Marrow Transplantation; DNA; Dogs

1965
[Use of nitrogen mustards in congenital hemolytic anemia; case report].
    Arquivos de clinica, 1951, Volume: 12, Issue:3

    Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Congenital; Mechlorethamine; Nitrogen Mustard Compound

1951
[Use of nitrogen mustards in congenital hemolitic anemia; case report].
    Revista brasileira de medicina, 1951, Volume: 8, Issue:5

    Topics: Anemia; Anemia, Hemolytic; Anemia, Neonatal; Humans; Infant, Newborn; Mechlorethamine; Nitrogen Must

1951
[Tentative treatment with nitrogen yperite in some childhood anemias with erythroblastosis; subacute erythremic myelosis and Cooley's anemia].
    Minerva medica, 1949, Sep-08, Volume: 40, Issue:44 Pt 2

    Topics: Anemia; beta-Thalassemia; Hematopoietic System; Humans; Leukemia, Erythroblastic, Acute; Mechloretha

1949
Marrow culture in diffusion chambers in rabbits. II. Effect of competing demands for red cell and white cell production on cell growth.
    Blood, 1978, Volume: 51, Issue:6

    Topics: Anemia; Animals; Bone Marrow Cells; Cells, Cultured; Endotoxins; Erythrocytes; Erythropoietin; Hemat

1978
Selective metaphasic arrest of erythroblasts by vincristine in patients receiving high doses of recombinant human erythropoietin for myelosuppressive anemia.
    Leukemia, 1992, Volume: 6 Suppl 4

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Erythroblasts; Erythropoietin; Hodgkin Disea

1992
The use of different drugs and combinations in the treatment of Hodgkin's disease.
    Series haematologica (1968), 1973, Volume: 6, Issue:2

    Topics: Administration, Oral; Anemia; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; I

1973
Combination chemotherapy of Hodgkin's disease in private practice.
    JAMA, 1972, Jul-17, Volume: 221, Issue:3

    Topics: Adolescent; Adult; Aged; Anemia; Biopsy; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Mid

1972