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mechlorethamine and Anaplastic Astrocytoma

mechlorethamine has been researched along with Anaplastic Astrocytoma in 8 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"Previous investigators have reported responses in 52% of patients treated with mechlorethamine (nitrogen mustard), vincristine, and procarbazine (MOP) for recurrent glioma."9.08Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results. ( Buckner, JC; Burch, PA; Dinapoli, RP; Galanis, E; Mailliard, JA; Morton, RF; Novotny, PJ; Rowland, KM; Schaefer, PL; Scheithauer, BW; Vukov, AM, 1998)
"The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma."8.78Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992)
"Previous investigators have reported responses in 52% of patients treated with mechlorethamine (nitrogen mustard), vincristine, and procarbazine (MOP) for recurrent glioma."5.08Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results. ( Buckner, JC; Burch, PA; Dinapoli, RP; Galanis, E; Mailliard, JA; Morton, RF; Novotny, PJ; Rowland, KM; Schaefer, PL; Scheithauer, BW; Vukov, AM, 1998)
"The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma."4.78Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992)
"The first child had hydrocephalus with an enhancing mass at the hypothalamus which followed the optic radiation to include the lateral geniculate body and medial temporal lobe."2.38Chemotherapeutic treatment of extensive optic pathway tumors in infants. ( Kretschmar, CS; Linggood, RM, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cangir, A3
Ragab, AH1
Steuber, P1
Land, VJ1
Berry, DH1
Krischer, JP1
Galanis, E1
Buckner, JC1
Burch, PA1
Schaefer, PL1
Dinapoli, RP1
Novotny, PJ1
Scheithauer, BW1
Rowland, KM1
Vukov, AM1
Mailliard, JA1
Morton, RF1
Coyle, T1
Bushunow, P1
Winfield, J1
Wright, J1
Graziano, S1
Kretschmar, CS1
Linggood, RM1
Stokes, DC1
Shenep, JL1
Horowitz, ME1
Hughes, WT1
van Eys, J2
Baram, TZ1
Bruner, JM1
Martinez-Prieto, J1
Coody, D1
Smith, B1
Mahaley, MS1
Woodhall, B1

Reviews

2 reviews available for mechlorethamine and Anaplastic Astrocytoma

ArticleYear
Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma.
    Cancer, 1992, May-15, Volume: 69, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Hypersensit

1992
Chemotherapeutic treatment of extensive optic pathway tumors in infants.
    Journal of neuro-oncology, 1991, Volume: 10, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Astrocytoma; Cerebrospinal Fluid Shunts; Ci

1991

Trials

1 trial available for mechlorethamine and Anaplastic Astrocytoma

ArticleYear
Phase II trial of nitrogen mustard, vincristine, and procarbazine in patients with recurrent glioma: North Central Cancer Treatment Group results.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Female; Glioma;

1998

Other Studies

5 other studies available for mechlorethamine and Anaplastic Astrocytoma

ArticleYear
Combination chemotherapy with vincristine (NSC-67574), procarbazine (NSC-77213), prednisone (NSC-10023) with or without nitrogen mustard (NSC-762)(MOPP vs OPP) in children with recurrent brain tumors.
    Medical and pediatric oncology, 1984, Volume: 12, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Follow-Up

1984
Presentation of Pneumocystis carinii pneumonia as unilateral hyperlucent lung.
    Chest, 1988, Volume: 94, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child, Preschool; Huma

1988
Salvage chemotherapy for recurrent primary brain tumors in children.
    The Journal of pediatrics, 1988, Volume: 113, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Chi

1988
MOPP regimen as primary chemotherapy for brain tumors in infants.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms;

1985
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
    Annals of surgery, 1967, Volume: 166, Issue:2

    Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carci

1967