mechlorethamine has been researched along with Amenorrhea in 6 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Amenorrhea: Absence of menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Buserelin (d-Ser-[TBU]6 LHRH ethylamide) was prescribed in two different dosage schedules to twenty men, and in a single dosage schedule to eight women." | 2.66 | Failure to preserve fertility in patients with Hodgkin's disease. ( Ahmed, R; Besser, GM; Crowther, D; Gregory, W; Malpas, JS; Rees, LH; Shalet, S; Smith, D; Waxman, JH; Wrigley, PF, 1987) |
| "Persistent amenorrhea has occurred in 11 of 24 patients (46 percent) treated with MOPP alone or MOPP plus radiation excluding the pelvis." | 1.26 | Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease. ( DeVita, VT; Hubbard, SM; Schilsky, RL; Sherins, RJ; Wesley, MN; Young, RC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giuseppe, L | 1 |
| Attilio, G | 1 |
| Edoardo, DN | 1 |
| Loredana, G | 1 |
| Cristina, L | 1 |
| Vincenzo, L | 1 |
| Dein, RA | 1 |
| Mennuti, MT | 1 |
| Kovach, P | 1 |
| Gabbe, SG | 1 |
| Waxman, JH | 2 |
| Terry, YA | 1 |
| Wrigley, PF | 2 |
| Malpas, JS | 2 |
| Rees, LH | 2 |
| Besser, GM | 2 |
| Lister, TA | 1 |
| Schilsky, RL | 1 |
| Sherins, RJ | 1 |
| Hubbard, SM | 1 |
| Wesley, MN | 1 |
| Young, RC | 1 |
| DeVita, VT | 1 |
| Clark, ST | 1 |
| Radford, JA | 1 |
| Crowther, D | 2 |
| Swindell, R | 1 |
| Shalet, SM | 1 |
| Ahmed, R | 1 |
| Smith, D | 1 |
| Gregory, W | 1 |
| Shalet, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University[NCT00902720] | Phase 4 | 25 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mechlorethamine and Amenorrhea
| Article | Year |
|---|---|
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
3 trials available for mechlorethamine and Amenorrhea
| Article | Year |
|---|---|
Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD).
Topics: Adolescent; Adult; Amenorrhea; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocol | 2007 |
Gonadal function following chemotherapy for Hodgkin's disease: a comparative study of MVPP and a seven-drug hybrid regimen.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Doxorub | 1995 |
Failure to preserve fertility in patients with Hodgkin's disease.
Topics: Amenorrhea; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Dogs; Female; Follic | 1987 |
2 other studies available for mechlorethamine and Amenorrhea
| Article | Year |
|---|---|
Gonadal function in Hodgkin's disease: long-term follow-up of chemotherapy.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Child; Drug Therapy, | 1982 |
Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Agents; Female; Follow-Up Studies; Hodgkin Disease; Ho | 1981 |