mechlorethamine has been researched along with Alopecia Areata in 5 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Alopecia Areata: Loss of scalp and body hair involving microscopically inflammatory patchy areas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alopecia areata is an autoimmune disease targeted at hair follicles with infiltrated T lymphocytes probably playing an important role in the pathogenesis." | 5.32 | Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes. ( Bernardo, O; Cao, L; Chen, Y; Chung, S; Lui, H; Shapiro, J; Sundberg, JP; Tang, L, 2003) |
| "Alopecia areata is regarded as a tissue-restricted autoimmune disease of hair follicles in which follicular activity is arrested because of the continued activity of lymphocytic infiltrates." | 2.42 | Old wine in new bottles: reviving old therapies for alopecia areata using rodent models. ( Lui, H; Shapiro, J; Sundberg, JP; Tang, L, 2003) |
| "Alopecia areata is an autoimmune disease targeted at hair follicles with infiltrated T lymphocytes probably playing an important role in the pathogenesis." | 1.32 | Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes. ( Bernardo, O; Cao, L; Chen, Y; Chung, S; Lui, H; Shapiro, J; Sundberg, JP; Tang, L, 2003) |
| "Its efficacy in treating alopecia areata was reported in an uncontrolled study." | 1.32 | Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study. ( Bernardo, O; Lui, H; Shapiro, J; Tang, L, 2003) |
| "Systemic symptoms of Hodgkin's disease were present for 6 months, and rapidly developing patchy hair loss of the scalp was present for 2 weeks prior to presentation." | 1.28 | Simultaneously occurring alopecia areata and Hodgkin's lymphoma: complete remission of both diseases with MOPP/ABV chemotherapy. ( Berk, MA; Chan, PD; Kucuk, O; Singh, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, L | 3 |
| Cao, L | 1 |
| Bernardo, O | 2 |
| Chen, Y | 1 |
| Sundberg, JP | 2 |
| Lui, H | 3 |
| Chung, S | 1 |
| Shapiro, J | 3 |
| Chan, PD | 1 |
| Berk, MA | 1 |
| Kucuk, O | 1 |
| Singh, S | 1 |
| Arrazola, JM | 1 |
| Sendagorta, E | 1 |
| Harto, A | 1 |
| Ledo, A | 1 |
1 review available for mechlorethamine and Alopecia Areata
| Article | Year |
|---|---|
Old wine in new bottles: reviving old therapies for alopecia areata using rodent models.
Topics: Alopecia Areata; Animals; Anthralin; Disease Models, Animal; Mechlorethamine; Rodentia | 2003 |
4 other studies available for mechlorethamine and Alopecia Areata
| Article | Year |
|---|---|
Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes.
Topics: Alkylating Agents; Alopecia Areata; Animals; Autoimmune Diseases; Cell Movement; Hair Follicle; Inte | 2003 |
Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study.
Topics: Administration, Topical; Adult; Alkylating Agents; Alopecia Areata; Female; Humans; Male; Mechloreth | 2003 |
Simultaneously occurring alopecia areata and Hodgkin's lymphoma: complete remission of both diseases with MOPP/ABV chemotherapy.
Topics: Adult; Alopecia Areata; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Bleomyc | 1992 |
Treatment of alopecia areata with topical nitrogen mustard.
Topics: Administration, Topical; Adolescent; Adult; Aged; Alopecia Areata; Female; Humans; Male; Mechloretha | 1985 |