mechlorethamine has been researched along with Allergy, Drug in 31 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma." | 8.78 | Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992) |
| "Seventy-six patients with mycosis fungoides (MF) were given topical mechlorethamine hydrochloride therapy." | 7.67 | Response of mycosis fungoides to topical chemotherapy with mechlorethamine. ( Dubin, N; Parnes, RE; Ramsay, DL, 1984) |
| "One hundred seventeen patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride." | 7.67 | Topical mechlorethamine therapy for early stage mycosis fungoides. ( Halperin, PS; Ramsay, DL; Zeleniuch-Jacquotte, A, 1988) |
| "Eight patients with psoriasis who had developed contact allergy to mechlorethamine hydrochloride (nitrogen mustard) were subjected to a regimen of intravenous infusion of small amounts of the drug in an attempt to produce desensitization." | 7.65 | Intravenous desensitization to mechlorethamine in patients with psoriasis. ( Childers, RC; Halprin, KM; Kechijian, P; Pariser, DM; Taylor, JR, 1976) |
| "The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine, and procarbazine (MOP) for high-grade glioma." | 4.78 | Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma. ( Bushunow, P; Coyle, T; Graziano, S; Winfield, J; Wright, J, 1992) |
| "Seventy-six patients with mycosis fungoides (MF) were given topical mechlorethamine hydrochloride therapy." | 3.67 | Response of mycosis fungoides to topical chemotherapy with mechlorethamine. ( Dubin, N; Parnes, RE; Ramsay, DL, 1984) |
| "One hundred seventeen patients with mycosis fungoides were treated with topical mechlorethamine hydrochloride." | 3.67 | Topical mechlorethamine therapy for early stage mycosis fungoides. ( Halperin, PS; Ramsay, DL; Zeleniuch-Jacquotte, A, 1988) |
| "A group of 220 patients with mycosis fungoides (MF) and other lymphomatous diseases was treated with sustained topical applications of dilute aqueous solutions of mechlorethamine hydrochloride for intervals ranging in excess of seven years." | 3.65 | Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results. ( Asbell, SO; Grekin, DA; Johnson, WC; Van Scott, EJ; Vonderheid, EC, 1977) |
| "Eight patients with psoriasis who had developed contact allergy to mechlorethamine hydrochloride (nitrogen mustard) were subjected to a regimen of intravenous infusion of small amounts of the drug in an attempt to produce desensitization." | 3.65 | Intravenous desensitization to mechlorethamine in patients with psoriasis. ( Childers, RC; Halprin, KM; Kechijian, P; Pariser, DM; Taylor, JR, 1976) |
| "Twenty-six patients with mycosis fungoides were treated topically with three nitrosourea compounds: carmustine (BCNU), lomustine (CCNU), and 1-methyl-1-nitrosourea." | 3.65 | Treatment of mycosis fungoides with topical nitrosourea compounds: Further studies. ( Epstein, EH; Zackheim, HS, 1975) |
| "A patient with advanced Hodgkin's disease being treated with MOPP chemotherapy presented with delayed life-threatening pulmonary toxicity secondary to procarbazine." | 1.28 | Delayed life-threatening pneumonitis secondary to procarbazine. ( Alvarez, S; Ancalmo, N; Brooks, BJ; Grinton, SF; Hendler, NB, 1990) |
| "A patient suffering from Hodgkin's disease exhibiting acute allergic reaction to vincristine sulfate with mild to moderate dermatologic and cardiovascular signs is described." | 1.27 | Acute allergic reaction due to vincristine sulfate. A case report. ( Gassel, WD; Gropp, C; Havemann, K, 1984) |
| "Procarbazine may have been the responsible agent." | 1.26 | Diffuse pulmonary disease after therapy with nitrogen mustard, vincristine, procarbazine, and prednisone. ( Armstrong, JD; Farney, RJ; Hammer, S; Morris, AH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (90.32) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EZRIN, C | 1 |
| WARD, JR | 1 |
| CLOUD, RS | 1 |
| KRAWITT, EL | 1 |
| JONES, RS | 1 |
| PLIESS, G | 1 |
| Michel, H | 1 |
| Waldorf, DS | 1 |
| Haynes, HA | 1 |
| Van Scott, EJ | 6 |
| Brauer, MJ | 1 |
| McEvoy, BF | 1 |
| Mitus, WJ | 1 |
| Nusbaum, BP | 1 |
| Edwards, EK | 1 |
| Horwitz, SN | 1 |
| Frost, P | 1 |
| Ramsay, DL | 2 |
| Parnes, RE | 1 |
| Dubin, N | 1 |
| Gassel, WD | 1 |
| Gropp, C | 1 |
| Havemann, K | 1 |
| Wilson, KS | 1 |
| Alexander, S | 1 |
| Vonderheid, EC | 2 |
| Ekbote, SK | 1 |
| Kerrigan, K | 1 |
| Kalmanson, JD | 2 |
| Rook, AH | 1 |
| Abrams, JT | 1 |
| Kopf, AW | 1 |
| Bart, RS | 1 |
| Pascher, F | 1 |
| Farney, RJ | 1 |
| Morris, AH | 1 |
| Armstrong, JD | 1 |
| Hammer, S | 1 |
| Johnson, WC | 1 |
| Grekin, DA | 1 |
| Asbell, SO | 1 |
| Fisher, AA | 1 |
| Pariser, DM | 1 |
| Childers, RC | 1 |
| Kechijian, P | 1 |
| Halprin, KM | 1 |
| Taylor, JR | 1 |
| Zackheim, HS | 2 |
| Epstein, EH | 1 |
| Purdy, MJ | 2 |
| Coyle, T | 1 |
| Bushunow, P | 1 |
| Winfield, J | 1 |
| Wright, J | 1 |
| Graziano, S | 1 |
| Brooks, BJ | 1 |
| Hendler, NB | 1 |
| Alvarez, S | 1 |
| Ancalmo, N | 1 |
| Grinton, SF | 1 |
| Halperin, PS | 1 |
| Zeleniuch-Jacquotte, A | 1 |
| Amiel, JL | 1 |
| Mathé, G | 1 |
| Daughters, D | 1 |
| Zackheim, H | 1 |
| Maibach, H | 1 |
| Yu, RJ | 1 |
| Cameron, JS | 1 |
| Arnold, JE | 1 |
| Farber, EM | 1 |
| Cox, AJ | 1 |
| Epstein, E | 1 |
| Ugel, AR | 1 |
| Winters, PL | 1 |
2 reviews available for mechlorethamine and Allergy, Drug
| Article | Year |
|---|---|
Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Drug Hypersensit | 1992 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath | 1971 |
2 trials available for mechlorethamine and Allergy, Drug
| Article | Year |
|---|---|
Psoriasis therapy. The effect of UV radiation on sensitization to mechlorethamine.
Topics: Administration, Topical; Aged; Clinical Trials as Topic; Dermatitis, Contact; Drug Hypersensitivity; | 1983 |
Effects of topical mechlorethamine on skin lesions of psoriasis.
Topics: Adult; Drug Hypersensitivity; Edema; Erythema; Female; Humans; Lactose; Male; Mechlorethamine; Middl | 1970 |
27 other studies available for mechlorethamine and Allergy, Drug
| Article | Year |
|---|---|
RESISTANCE AND ALLERGY TO INSULIN.
Topics: Adrenal Cortex Hormones; Diet; Drug Hypersensitivity; Humans; Hypersensitivity; Insulin; Insulin Ant | 1963 |
STUDIES ON ADJUVANT-INDUCED POLYARTHRITIS IN RATS. 3. THE EFFECT OF "IMMUNOSUPPRESSIVE AGENTS" ON ARTHRITIS AND TUBERCULIN HYPERSENSITIVITY.
Topics: Adjuvants, Immunologic; Allergy and Immunology; Arthritis; Drug Hypersensitivity; Immunosuppressive | 1964 |
[DEVELOPMENTAL DISORDER OF THE SKELETON CAUSED BY NITROGEN MUSTARD AND THE EFFECT OF VITAMIN E].
Topics: Abnormalities, Drug-Induced; Bone and Bones; Bone Development; Drug Hypersensitivity; Mechlorethamin | 1964 |
[Therapy of diabetes mellitus in the course of resistance to insulin or allergy to insulin].
Topics: Diabetes Mellitus; Dimercaprol; Drug Hypersensitivity; Humans; Insulin; Insulin Resistance; Mechlore | 1967 |
Cutaneous hypersensitivity and desensitization to mechlorethamine in patients with mycosis fungoides lymphoma.
Topics: Cyclophosphamide; Dermatitis, Contact; Desensitization, Immunologic; Dosage Forms; Drug Hypersensiti | 1967 |
Hypersensitivity to nitrogen mustards in the form of erythema multiforme. A unique adverse reaction.
Topics: Chlorambucil; Drug Hypersensitivity; Erythema Multiforme; Hodgkin Disease; Humans; Male; Mechloretha | 1967 |
Response of mycosis fungoides to topical chemotherapy with mechlorethamine.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Drug Hypersensitivity; Female; Humans; Hype | 1984 |
Acute allergic reaction due to vincristine sulfate. A case report.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Hyperse | 1984 |
Hypersensitivity to mechlorethamine.
Topics: Drug Hypersensitivity; Female; Humans; Mechlorethamine; Middle Aged | 1981 |
The prognostic significance of delayed hypersensitivity to dinitrochlorobenzene and mechlorethamine hydrochloride in cutaneous T cell lymphoma.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Dinitrochlorobenzene; Disease P | 1998 |
Development of more keratoacanthomas following skin testing with nitrogen mustard in a patient with the multiple keratoacanthoma syndrome.
Topics: Adult; Drug Hypersensitivity; Humans; Keratoacanthoma; Male; Mechlorethamine; Skin Tests; Time Facto | 1979 |
Systemic reactions to topically applied drugs.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Boric Acids; Child; Child, Preschool; | 1978 |
Diffuse pulmonary disease after therapy with nitrogen mustard, vincristine, procarbazine, and prednisone.
Topics: Adult; Biopsy; Drug Hypersensitivity; Female; Hodgkin Disease; Humans; Lung Diseases; Mechlorethamin | 1977 |
Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term results.
Topics: Administration, Topical; Aged; Desensitization, Immunologic; Dinitrochlorobenzene; Drug Hypersensiti | 1977 |
Urticarial and systemic reactions to contactants varying from hair bleach to seminal fluid.
Topics: Ammonium Sulfate; Benzophenones; Cephalosporins; Drug Hypersensitivity; Female; Humans; Mechloretham | 1977 |
Intravenous desensitization to mechlorethamine in patients with psoriasis.
Topics: Administration, Topical; Dermatitis, Contact; Desensitization, Immunologic; Drug Hypersensitivity; H | 1976 |
Treatment of mycosis fungoides with topical nitrosourea compounds: Further studies.
Topics: Administration, Topical; Adult; Aged; Bone Marrow; Carmustine; Cross Reactions; Drug Hypersensitivit | 1975 |
Topical mustine hydrochloride and psoriasis: a follow-up study.
Topics: Adolescent; Adult; Aged; Child; Desensitization, Immunologic; Drug Hypersensitivity; Female; Follow- | 1975 |
Delayed life-threatening pneumonitis secondary to procarbazine.
Topics: Adult; Alveolitis, Extrinsic Allergic; Antineoplastic Combined Chemotherapy Protocols; Diagnosis, Di | 1990 |
Topical mechlorethamine therapy for early stage mycosis fungoides.
Topics: Administration, Topical; Adult; Aged; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delay | 1988 |
[Chemotherapy of Hodgkin's disease].
Topics: Antineoplastic Agents; Bleomycin; Drug Hypersensitivity; Drug Therapy, Combination; Hodgkin Disease; | 1974 |
Complete remissions of mycosis fungoides lymphoma induced by topical nitrogen mustard (HN2). Control of delayed hypersensitivity to HN2 by desensitization and by induction of specific immunologic tolerance.
Topics: Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Immune Tolerance; Immunologic Tech | 1973 |
Urticaria and anaphylactoid reactions after topical application of mechlorethamine.
Topics: Aged; Anaphylaxis; Diphenhydramine; Drug Hypersensitivity; Epinephrine; Female; Humans; Mechloretham | 1973 |
Topical mustine hydrochloride and psoriasis.
Topics: Drug Hypersensitivity; Female; Humans; Male; Mechlorethamine; Middle Aged; Psoriasis; Solutions | 1973 |
Antimitotic, antigenic, and structural relationships of nitrogen mustard and its homologues.
Topics: Animals; Antigens; Cross Reactions; Drug Hypersensitivity; Epithelial Cells; Epithelium; Ethanolamin | 1974 |
Topical therapy of psoriasis with mechlorethamine.
Topics: Drug Hypersensitivity; Humans; Mechlorethamine; Microscopy, Electron; Psoriasis; Remission, Spontane | 1972 |
Responses of mycosis fungoides to intensive external treatment with nitrogen mustard.
Topics: Adult; Aged; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Leukocyte Count; Male | 1970 |