Page last updated: 2024-10-30

mechlorethamine and Aging

mechlorethamine has been researched along with Aging in 11 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Intervertebral disc degeneration (IDD) is a common and debilitating disorder that results in reduced flexibility of the spine, pain, and reduced mobility."1.36Accelerated aging of intervertebral discs in a mouse model of progeria. ( Alber, S; Bentley, D; Coehlo, P; Huard, J; Kang, J; Lee, J; Loppini, M; Niedernhofer, LJ; Robbins, PD; Robinson, A; Seo, HY; Sowa, G; Studer, R; Taylor, L; Usas, A; Vo, N; Wang, D; Watkins, SC, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vo, N1
Seo, HY1
Robinson, A1
Sowa, G1
Bentley, D1
Taylor, L1
Studer, R1
Usas, A1
Huard, J1
Alber, S1
Watkins, SC1
Lee, J1
Coehlo, P1
Wang, D1
Loppini, M1
Robbins, PD1
Niedernhofer, LJ1
Kang, J1
NAHUM, LH1
GOLDGRABER, MB1
KIRSNER, JB1
CONKLIN, JW1
UPTON, AC1
CHRISTENBERRY, KW1
Bito, LZ1
Geraudie, J1
Greenstein, RJ1
Wormser, U1
Kohen, R1
Moor, EV1
Eldad, A1
Gal, R1
Nyska, A1
Brodsky, B1
Murakami, K1
Ueda, Y1
Tsunoda, T1
Mikami, M1
Yamamoto, M1
Tardiff, RG1
Dubois, KP1

Reviews

1 review available for mechlorethamine and Aging

ArticleYear
Species differences in the responses of the eye to irritation and trauma: a hypothesis of divergence in ocular defense mechanisms, and the choice of experimental animals for eye research.
    Experimental eye research, 1984, Volume: 39, Issue:6

    Topics: Aging; Animals; Anterior Chamber; Aotus trivirgatus; Aqueous Humor; Biological Evolution; Blood; Cat

1984

Other Studies

10 other studies available for mechlorethamine and Aging

ArticleYear
Accelerated aging of intervertebral discs in a mouse model of progeria.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:12

    Topics: Aging; Animals; Apoptosis; Cellular Senescence; Disease Models, Animal; DNA-Binding Proteins; Endonu

2010
ROGER BACON and his cure for old age.
    Annals of the Royal College of Surgeons of England, 1956, Volume: 18, Issue:5

    Topics: Aging; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Famous Persons; Histo

1956
THE BLUEPRINTS OF LIFE'S ARCHITECTURE.
    Connecticut medicine, 1964, Volume: 28

    Topics: Aging; DNA; Genetics, Medical; Humans; Mechlorethamine; Radiation Genetics; RNA

1964
CARCINOMA OF THE COLON IN ULCERATIVE COLITIS.
    Cancer, 1964, Volume: 17

    Topics: Aged; Aging; Cell Biology; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Fluorouracil; Humans; Me

1964
FURTHER OBSERVATIONS ON LATE SOMATIC EFFECTS OF RADIOMIMETIC CHEMICALS AND X-RAYS IN MICE.
    Cancer research, 1965, Volume: 25

    Topics: Aging; Busulfan; Cataract; Female; Humans; Leukemia; Leukemia, Myeloid; Longevity; Lung Neoplasms; L

1965
Consequences of cell death after nitrogen mustard treatment on skeletal pelvic fin morphogenesis in the trout, Salmo Gairdneri (Pisces, Teleostei).
    Journal of morphology, 1981, Volume: 170, Issue:2

    Topics: Aging; Animals; Bone Development; Cell Survival; Epidermis; Mechlorethamine; Mesoderm; Salmonidae; T

1981
Age, as well as cell turnover kinetics, regulates brain/gut repair.
    Mechanisms of ageing and development, 1993, Volume: 69, Issue:3

    Topics: Aging; Animals; Brain; Carmustine; Cell Cycle; Cholecystokinin; DNA; DNA Damage; Intestinal Mucosa;

1993
Noninvasive procedure for in situ determination of skin surface aspartic proteinase activity in animals; implications for human skin.
    Archives of dermatological research, 1997, Volume: 289, Issue:12

    Topics: Aging; Alkylating Agents; Animals; Aspartic Acid Endopeptidases; Cathepsin D; Enzyme Inhibitors; Gui

1997
[Addenda to the study of the effect of carcinostatic drugs on human beings. II. Variations in peripheral blood in young and adult albino rats after administration of sublethal doses, equally divided per body weight].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1968, Feb-01, Volume: 72, Issue:2

    Topics: Aging; Animals; Blood Cell Count; Blood Cells; Body Weight; Hemoglobins; Mechlorethamine; Methotrexa

1968
Inhibition of hepatic microsomal enzymes by alkylating agents.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 177, Issue:2

    Topics: Aging; Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Enzyme Induction; Enzymes; Liver; Mal

1969