Page last updated: 2024-10-30

mechlorethamine and Adverse Drug Event

mechlorethamine has been researched along with Adverse Drug Event in 16 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Research Excerpts

ExcerptRelevanceReference
"The causes of death were Hodgkin's lymphoma in 36 patients, second neoplasms in 12, cardiorespiratory diseases in 4, pulmonary diseases in 2, and unknown in 6."2.72MOPPEBVCAD chemotherapy with limited and conditioned radiotherapy in advanced Hodgkin's lymphoma: 10-year results, late toxicity, and second tumors. ( Broglia, C; Cavanna, L; Chisesi, T; Corazza, GR; Corbella, F; Federico, M; Gobbi, PG; Iannitto, E; La Sala, A; Levis, A; Molica, S; Pavone, V; Sacchi, S; Valentino, F, 2006)
"The eight patients who reported pretreatment nausea had more extensive disease than the other patients and had received twice as much chemotherapy."1.26Pretreatment nausea in cancer chemotherapy: a conditioned response? ( Carli, T; Curtis, GC; Kleinman, PD; Nesse, RM, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Prag Naveh, H1
Amitay-Laish, I1
Zidan, O1
Leshem, YA1
Sherman, S1
Noyman, Y1
Taieb, J1
Didkovsky, E1
Hodak, E1
Sharma, M1
Vijayaraghavan, R1
Gautam, A1
WOLFSON, S1
OLNEY, MB1
MATHE, G1
BERNARD, J1
DAVID, G2
TANKA, D1
FIAM, B1
CATTANEO, I2
NINNI, M2
BISOTTI, PL1
BARATTA, PF1
LORENZINI, R1
BUSANI, L1
Gobbi, PG1
Broglia, C1
Levis, A1
La Sala, A1
Valentino, F1
Chisesi, T1
Sacchi, S1
Corbella, F1
Cavanna, L1
Iannitto, E1
Pavone, V1
Molica, S1
Corazza, GR1
Federico, M1
Nesse, RM1
Carli, T1
Curtis, GC1
Kleinman, PD1
DeVita, VT1
Arseneau, JC1
Sherins, RJ1
Canellos, GP1
Young, RC1
Grundmann, E1
Fritzsche, R1
Saslaw, S1
Carlisle, HN1

Trials

1 trial available for mechlorethamine and Adverse Drug Event

ArticleYear
MOPPEBVCAD chemotherapy with limited and conditioned radiotherapy in advanced Hodgkin's lymphoma: 10-year results, late toxicity, and second tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jan-15, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

2006

Other Studies

15 other studies available for mechlorethamine and Adverse Drug Event

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Real-life experience with chlormethine gel for early-stage mycosis fungoides with emphasis on types and management of cutaneous side-effects
    The Journal of dermatological treatment, 2022, Volume: 33, Issue:4

    Topics: Adult; Dermatitis, Contact; Dermatologic Agents; Drug-Related Side Effects and Adverse Reactions; Hu

2022
DRDE-07 and its analogues as promising cytoprotectants to nitrogen mustard (HN-2)--an alkylating anticancer and chemical warfare agent.
    Toxicology letters, 2009, Aug-10, Volume: 188, Issue:3

    Topics: Amifostine; Animals; Antidotes; Antineoplastic Agents, Alkylating; Body Weight; Chemical Warfare Age

2009
Accidental ingestion of a toxic dose of chlorambucil; report of a case in a child.
    Journal of the American Medical Association, 1957, Sep-21, Volume: 165, Issue:3

    Topics: Child; Chlorambucil; Drug-Related Side Effects and Adverse Reactions; Humans; Mechlorethamine; Nitro

1957
[Attempted protection by isologous or homologous hematopoietic cells against the toxicity of methyl-bis-chlorethylamine in the mouse].
    Revue francaise d'etudes cliniques et biologiques, 1958, Volume: 3, Issue:5

    Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Diploidy; Drug-Related Side Effects and Adverse R

1958
[DATA ON THE RADIOMIMETIC EFFECT OF NITROGEN MUSTARD. FUNCTION CHANGES IN THE ADRENAL GLANDS IN NITROGEN MUSTARD POISONING].
    Radiobiologia, radiotherapia, 1964, Volume: 5

    Topics: Adrenal Glands; Blood Chemical Analysis; Corticosterone; Drug-Related Side Effects and Adverse React

1964
[EFFECT OF NITROGEN MUSTARD GAS POISONING ON SERUM PROTEINS].
    Radiobiologia, radiotherapia, 1964, Volume: 5

    Topics: Blood Proteins; Drug-Related Side Effects and Adverse Reactions; Gas Poisoning; Mechlorethamine; Nit

1964
[Behavior of the leukocyte oxidase and peroxidase in experimental nitrogen mustard poisoning].
    Haematologica, 1950, Volume: 34, Issue:6

    Topics: Drug-Related Side Effects and Adverse Reactions; Leukocytes; Mechlorethamine; Nitrogen Mustard Compo

1950
[Role of the spleen in leukocyte regulation; behavior of the leukolytic activity of blood serum in experimental nitrogen mustard poisoning in relation to splenectomy].
    Haematologica, 1950, Volume: 34, Issue:7

    Topics: Drug-Related Side Effects and Adverse Reactions; Leukocytes; Mechlorethamine; Nitrogen Mustard Compo

1950
[Effect of hexamethylenetetramine on the behavior of the peripheral blood crasis in experimental nitrogen mustard poisoning].
    Bollettino della Societa italiana di biologia sperimentale, 1950, Volume: 26, Issue:7

    Topics: Drug-Related Side Effects and Adverse Reactions; Mechlorethamine; Methenamine; Nitrogen Mustard Comp

1950
[Plasma protein crasis in chronic nitrogen mustard poisoning (dichlorodiethylmethylamine)].
    Giornale di clinica medica, 1951, Volume: 32, Issue:4

    Topics: Blood Proteins; Drug-Related Side Effects and Adverse Reactions; Humans; Mechlorethamine; Nitrogen M

1951
Pretreatment nausea in cancer chemotherapy: a conditioned response?
    Psychosomatic medicine, 1980, Volume: 42, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Conditioning, Psycholo

1980
Intensive chemotherapy for Hodgkin's disease: long-term complications.
    National Cancer Institute monograph, 1973, Volume: 36

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; E

1973
[Pathology of treated Hodgkin's disease. A retrospective study (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Feb-15, Volume: 99, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Autopsy; Child; Child, Preschool; Drug Therapy, Combination; D

1974
Nonhuman primates in evaluation of hematotoxicity.
    Annals of the New York Academy of Sciences, 1969, Jul-03, Volume: 162, Issue:1

    Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug-Related Side Effects and Adver

1969