mechlorethamine has been researched along with Acute Lung Injury in 5 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline is a TNFα inhibitor known to suppress inflammation." | 5.40 | Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014) |
| "Pentoxifylline is a TNFα inhibitor known to suppress inflammation." | 1.40 | Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Rosas, L | 1 |
| Li, Z | 1 |
| Bian, Z | 1 |
| Li, X | 1 |
| Choi, K | 1 |
| Cai, C | 1 |
| Zhou, X | 1 |
| Tan, T | 1 |
| Bergdall, V | 1 |
| Whitson, B | 1 |
| Davis, I | 1 |
| Ma, J | 1 |
| Sunil, VR | 2 |
| Vayas, KN | 2 |
| Radbel, J | 1 |
| Abramova, E | 1 |
| Gow, A | 1 |
| Laskin, JD | 4 |
| Laskin, DL | 4 |
| Murray, A | 1 |
| Gow, AJ | 3 |
| Venosa, A | 2 |
| Andres, J | 1 |
| Malaviya, R | 2 |
| Adler, D | 1 |
| Yurkow, E | 1 |
| Smith, LC | 1 |
| Zarbl, H | 1 |
| Cervelli, JA | 1 |
| Hall, L | 1 |
| Massa, CB | 1 |
5 other studies available for mechlorethamine and Acute Lung Injury
| Article | Year |
|---|---|
MG53 attenuates nitrogen mustard-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Endothelial Cells; Lung; Mechlorethamine; Membrane Proteins; Mice; Recom | 2022 |
Impaired energy metabolism and altered functional activity of alveolar type II epithelial cells following exposure of rats to nitrogen mustard.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Energy Metabolism; Male; Mechlorethamine; Oxi | 2022 |
Assessment of mustard vesicant lung injury and anti-TNF-α efficacy in rodents using live-animal imaging.
Topics: Acute Lung Injury; Animals; Antibodies, Monoclonal, Murine-Derived; Irritants; Magnetic Resonance Im | 2020 |
Macrophage activation in the lung during the progression of nitrogen mustard induced injury is associated with histone modifications and altered miRNA expression.
Topics: Acute Lung Injury; Animals; Gene Expression; Histones; Lung; Macrophage Activation; Male; Mechloreth | 2021 |
Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation.
Topics: Acute Lung Injury; Animals; Chemical Warfare Agents; Cyclooxygenase 2; Heme Oxygenase-1; Irritants; | 2014 |