Page last updated: 2024-10-30

mechlorethamine and Acute Lung Injury

mechlorethamine has been researched along with Acute Lung Injury in 5 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).

Research Excerpts

ExcerptRelevanceReference
"Pentoxifylline is a TNFα inhibitor known to suppress inflammation."5.40Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014)
"Pentoxifylline is a TNFα inhibitor known to suppress inflammation."1.40Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. ( Cervelli, JA; Gow, AJ; Hall, L; Laskin, DL; Laskin, JD; Malaviya, R; Massa, CB; Sunil, VR; Vayas, KN, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's4 (80.00)2.80

Authors

AuthorsStudies
Li, H1
Rosas, L1
Li, Z1
Bian, Z1
Li, X1
Choi, K1
Cai, C1
Zhou, X1
Tan, T1
Bergdall, V1
Whitson, B1
Davis, I1
Ma, J1
Sunil, VR2
Vayas, KN2
Radbel, J1
Abramova, E1
Gow, A1
Laskin, JD4
Laskin, DL4
Murray, A1
Gow, AJ3
Venosa, A2
Andres, J1
Malaviya, R2
Adler, D1
Yurkow, E1
Smith, LC1
Zarbl, H1
Cervelli, JA1
Hall, L1
Massa, CB1

Other Studies

5 other studies available for mechlorethamine and Acute Lung Injury

ArticleYear
MG53 attenuates nitrogen mustard-induced acute lung injury.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:7

    Topics: Acute Lung Injury; Animals; Endothelial Cells; Lung; Mechlorethamine; Membrane Proteins; Mice; Recom

2022
Impaired energy metabolism and altered functional activity of alveolar type II epithelial cells following exposure of rats to nitrogen mustard.
    Toxicology and applied pharmacology, 2022, 12-01, Volume: 456

    Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Energy Metabolism; Male; Mechlorethamine; Oxi

2022
Assessment of mustard vesicant lung injury and anti-TNF-α efficacy in rodents using live-animal imaging.
    Annals of the New York Academy of Sciences, 2020, Volume: 1480, Issue:1

    Topics: Acute Lung Injury; Animals; Antibodies, Monoclonal, Murine-Derived; Irritants; Magnetic Resonance Im

2020
Macrophage activation in the lung during the progression of nitrogen mustard induced injury is associated with histone modifications and altered miRNA expression.
    Toxicology and applied pharmacology, 2021, 07-15, Volume: 423

    Topics: Acute Lung Injury; Animals; Gene Expression; Histones; Lung; Macrophage Activation; Male; Mechloreth

2021
Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation.
    Experimental and molecular pathology, 2014, Volume: 97, Issue:1

    Topics: Acute Lung Injury; Animals; Chemical Warfare Agents; Cyclooxygenase 2; Heme Oxygenase-1; Irritants;

2014