mechlorethamine has been researched along with Acute Disease in 31 studies
nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most patients with early-stage Hodgkin's disease can now be cured by one of several therapeutic approaches." | 2.37 | Early-stage Hodgkin's disease: current approaches to treatment. ( MacKenzie, R; Rusthoven, JJ, 1985) |
| "Risk of leukemia was 0." | 1.30 | The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con ( Anselmo, AP; Baroni, CD; Bernasconi, C; Brusamolino, E; Klersy, C; Lazzarino, M; Lunghi, F; Mandelli, F; Maurizi-Enrici, R; Orlandi, E; Pagnucco, G; Santoro, M, 1998) |
| "Hodgkin's disease is curable in the majority of patients, although a proportion of patients are resistant to or relapse after initial therapy." | 1.30 | High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML. ( Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D, 1999) |
| "Patients who had a relapse of Hodgkin's disease did not have an increased incidence of second malignancy." | 1.27 | Second malignancy complicating Hodgkin's disease. ( Mercier, JP; Tawil, E, 1983) |
| "Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow." | 1.27 | Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985) |
| "Malignant myelosclerosis or acute myelofibrosis is a rare acute myeloproliferative disorder characterized by pancytopenia, myeloblastosis and marrow fibrosis." | 1.26 | Malignant myelosclerosis (acute myelofibrosis): report of two cases following cytotoxic chemotherapy. ( Ali, NO; Janes, WO, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (58.06) | 18.7374 |
| 1990's | 9 (29.03) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goswami, DG | 1 |
| Kant, R | 1 |
| Ammar, DA | 1 |
| Kumar, D | 1 |
| Enzenauer, RW | 1 |
| Petrash, JM | 1 |
| Tewari-Singh, N | 1 |
| Agarwal, R | 1 |
| Metayer, C | 1 |
| Curtis, RE | 1 |
| Vose, J | 1 |
| Sobocinski, KA | 1 |
| Horowitz, MM | 1 |
| Bhatia, S | 1 |
| Fay, JW | 1 |
| Freytes, CO | 1 |
| Goldstein, SC | 1 |
| Herzig, RH | 1 |
| Keating, A | 1 |
| Miller, CB | 1 |
| Nevill, TJ | 1 |
| Pecora, AL | 1 |
| Rizzo, JD | 1 |
| Williams, SF | 1 |
| Li, CY | 1 |
| Travis, LB | 1 |
| Weisdorf, DJ | 1 |
| HARRIS, MW | 1 |
| PORTER, FS | 1 |
| HOLOWACH, J | 1 |
| THURMAN, WG | 1 |
| BLICHARSKI, J | 1 |
| WUERFEL, J | 1 |
| Valagussa, P | 1 |
| Santoro, A | 1 |
| Fossati Bellani, F | 1 |
| Franchi, F | 1 |
| Banfi, A | 1 |
| Bonadonna, G | 1 |
| Körbling, M | 1 |
| Hunstein, W | 1 |
| Tawil, E | 1 |
| Mercier, JP | 1 |
| Aisenberg, AC | 1 |
| Redei, I | 1 |
| Mangan, KF | 1 |
| Ming, PL | 1 |
| Mullaney, MT | 1 |
| Rao, PN | 1 |
| Goldberg, SL | 1 |
| Klumpp, TR | 1 |
| Tsodikov, A | 1 |
| Loeffler, M | 1 |
| Yakovlev, A | 1 |
| Brusamolino, E | 1 |
| Anselmo, AP | 1 |
| Klersy, C | 1 |
| Santoro, M | 1 |
| Orlandi, E | 1 |
| Pagnucco, G | 1 |
| Lunghi, F | 1 |
| Maurizi-Enrici, R | 1 |
| Baroni, CD | 1 |
| Lazzarino, M | 1 |
| Mandelli, F | 1 |
| Bernasconi, C | 1 |
| Klapper, SR | 1 |
| Jordan, DR | 1 |
| McLeish, W | 1 |
| Pelletier, C | 1 |
| Lemoli, RM | 1 |
| Visani, G | 1 |
| Leopardi, G | 1 |
| Motta, MR | 1 |
| Rizzi, S | 1 |
| Testoni, N | 1 |
| Curti, A | 1 |
| Tura, S | 1 |
| Harrison, CN | 1 |
| Gregory, W | 1 |
| Hudson, GV | 1 |
| Devereux, S | 1 |
| Goldstone, AH | 1 |
| Hancock, B | 1 |
| Winfield, D | 1 |
| MacMillan, AK | 1 |
| Hoskin, P | 1 |
| Newland, AC | 1 |
| Milligan, D | 1 |
| Linch, DC | 1 |
| Luo, Q | 1 |
| Cheung, AK | 1 |
| Kamerath, CD | 1 |
| Reimer, LG | 1 |
| Leypoldt, JK | 1 |
| Avilés, A | 3 |
| Neri, N | 1 |
| Ali, NO | 1 |
| Janes, WO | 1 |
| Olenchock, SA | 1 |
| Mentnech, MS | 1 |
| Mull, JC | 1 |
| Gladish, ME | 1 |
| Green, FH | 1 |
| Manor, PC | 1 |
| Bergsagel, DE | 1 |
| Pruzanski, W | 1 |
| Grant, MD | 1 |
| Coleman, M | 1 |
| Clough, JD | 1 |
| Díaz-Maqueo, JC | 2 |
| Ayala, JR | 1 |
| Cortés, HD | 1 |
| García, EL | 2 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| Longo, DL | 1 |
| Duffey, PL | 1 |
| DeVita, VT | 1 |
| Wiernik, PH | 1 |
| Hubbard, SM | 1 |
| Phares, JC | 1 |
| Bastian, AW | 1 |
| Jaffe, ES | 1 |
| Young, RC | 1 |
| Boccaccio, P | 1 |
| Rosa, F | 1 |
| Casciaro, S | 1 |
| D'Elia, P | 1 |
| Romagnoli, M | 1 |
| Ghio, R | 1 |
| Sizoo, W | 1 |
| Hagenbeek, A | 1 |
| Löwenberg, B | 1 |
| Mauch, PM | 1 |
| Canellos, GP | 1 |
| Rosenthal, DS | 1 |
| Hellman, S | 1 |
| Rusthoven, JJ | 1 |
| MacKenzie, R | 1 |
| Whitney, MS | 1 |
| Boon, GD | 1 |
| Rebar, AH | 1 |
| Ford, RB | 1 |
| Pedersen-Bjergaard, J | 1 |
| Ersbøll, J | 1 |
| Sørensen, HM | 1 |
| Keiding, N | 1 |
| Larsen, SO | 1 |
| Philip, P | 1 |
| Larsen, MS | 1 |
| Schultz, H | 1 |
| Nissen, NI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mechlorethamine and Acute Disease
| Article | Year |
|---|---|
In vitro chemoseparation as part of autologous bone marrow transplantation (ABMT) in hematologic malignancy.
Topics: Acute Disease; Animals; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Disease Models, | 1984 |
Early-stage Hodgkin's disease: current approaches to treatment.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fem | 1985 |
1 trial available for mechlorethamine and Acute Disease
| Article | Year |
|---|---|
Treatment of advanced-stage Hodgkin's disease: alternating noncrossresistant MOPP/CABS is not superior to MOPP.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dose-Re | 1991 |
28 other studies available for mechlorethamine and Acute Disease
| Article | Year |
|---|---|
Acute corneal injury in rabbits following nitrogen mustard ocular exposure.
Topics: Acute Disease; Animals; Chemical Warfare Agents; Cornea; Corneal Injuries; Cyclooxygenase 2; Humans; | 2019 |
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth | 2003 |
Use of nitrogen mustards during acute hepatitis.
Topics: Acute Disease; Hepatitis; Hepatitis A; Hodgkin Disease; Mechlorethamine; Nitrogen Mustard Compounds | 1953 |
Uracil mustard therapy in acute leukemia in children.
Topics: Acute Disease; Child; Infant; Leukemia; Mechlorethamine; Nitrogen Mustard Compounds; Uracil Mustard | 1962 |
[A case of acute miliary tuberculosis treated by small doses of streptomycin and nitrogranulogen].
Topics: Acute Disease; Mechlorethamine; Nitrogen Mustard Compounds; Streptomycin; Tuberculosis; Tuberculosis | 1951 |
Absence of treatment-induced second neoplasms after ABVD in Hodgkin's disease.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Bleomycin; Child; Child, Preschool; Daca | 1982 |
Second malignancy complicating Hodgkin's disease.
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cycloph | 1983 |
Acute nonlymphocytic leukemia after treatment for Hodgkin's disease.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1983 |
Detection of a dormant 20q- leukemia clone in bone marrow cultures with hematopoietic growth factors: implications for secondary leukemia post-transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; An | 1997 |
A cure model with time-changing risk factor: an application to the analysis of secondary leukaemia. A report from the International Database on Hodgkin's Disease.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Fr | 1998 |
The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con
Topics: Abdomen; Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; | 1998 |
Unilateral proptosis in an immunocompetent man as the initial clinical manifestation of systemic Hodgkin disease.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Exophthalmos; | 1999 |
Autologous transplantation of chemotherapy-purged PBSC collections from high-risk leukemia patients: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow Purging; Busulfan; Combined Mod | 1999 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; | 1999 |
Increased protein loss during peritonitis associated with peritoneal dialysis is neutrophil dependent.
Topics: Acute Disease; Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Movement; Escherichia coli Infec | 2000 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
Malignant myelosclerosis (acute myelofibrosis): report of two cases following cytotoxic chemotherapy.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Glom | 1979 |
Complement, polymorphonuclear leukocytes and platelets in acute experimental respiratory reactions to Aspergillus.
Topics: Acute Disease; Aerosols; Animals; Antigens, Fungal; Aspergillus; Blood Cell Count; Blood Platelets; | 1979 |
Treatment of plasma cell myeloma with cytotoxic agents.
Topics: Acute Disease; Alkylating Agents; Bence Jones Protein; Bone Neoplasms; Carmustine; Cell Count; Cyclo | 1975 |
Hodgkin disease with acute lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukemi | 1975 |
Acute systemic lupus erythematosus in IgA deficiency. Mechlorethamine hydrochloride therapy.
Topics: Acute Disease; Adolescent; Antibodies, Antinuclear; Dysgammaglobulinemia; Humans; Immunoglobulin A; | 1975 |
Hodgkin's disease and acute leukemia. Is it a true association?
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil | 1992 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
[Acute leukemia in patients treated for Hodgkin's disease].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Human | 1988 |
[Myelodysplastic syndromes: a group of preleukemic disorders].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia | 1987 |
Reduction of fatal complications from combined modality therapy in Hodgkin's disease.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Pro | 1985 |
Evaluation of a spectrophotometric method for canine serum lipase determination.
Topics: Acute Disease; Animals; Clinical Enzyme Tests; Dithionitrobenzoic Acid; Dog Diseases; Dogs; Evaluati | 1986 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |