mecamylamine has been researched along with Reperfusion Injury in 2 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Global cerebral ischemia/reperfusion (GCI/R) injury encompasses complex pathophysiological sequalae, inducing loss of hippocampal neurons and behavioural deficits." | 5.40 | Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice. ( Katyal, A; Rai, S; Ray, RS, 2014) |
| "Global cerebral ischemia/reperfusion (GCI/R) injury encompasses complex pathophysiological sequalae, inducing loss of hippocampal neurons and behavioural deficits." | 1.40 | Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice. ( Katyal, A; Rai, S; Ray, RS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ray, RS | 1 |
| Rai, S | 1 |
| Katyal, A | 1 |
| Lorrio, S | 1 |
| Sobrado, M | 1 |
| Arias, E | 1 |
| Roda, JM | 1 |
| García, AG | 1 |
| López, MG | 1 |
2 other studies available for mecamylamine and Reperfusion Injury
| Article | Year |
|---|---|
Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice.
Topics: Acetylcholinesterase; Animals; Brain Ischemia; Choline O-Acetyltransferase; Cholinergic Antagonists; | 2014 |
Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils.
Topics: Animals; Apoptosis; Brain Ischemia; Carotid Artery, Common; Caspase 3; Galantamine; Gerbillinae; Hip | 2007 |