Page last updated: 2024-10-30

mecamylamine and Recrudescence

mecamylamine has been researched along with Recrudescence in 4 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Research Excerpts

ExcerptRelevanceReference
" We compared smokers with schizophrenia (SS; n=27) and control smokers (CS; n=26) on smoking and psychiatric outcomes at baseline, during acute smoking abstinence and reinstatement, and with pre-treatment using the nicotinic acetylcholine receptor (nAChR) antagonist mecamylamine (MEC) in a human laboratory setting."9.12Effects of acute abstinence, reinstatement, and mecamylamine on biochemical and behavioral measures of cigarette smoking in schizophrenia. ( Creeden, CL; George, TP; Jatlow, PI; Sacco, KA; Vessicchio, JC; Weinberger, AH, 2007)
" We compared smokers with schizophrenia (SS; n=27) and control smokers (CS; n=26) on smoking and psychiatric outcomes at baseline, during acute smoking abstinence and reinstatement, and with pre-treatment using the nicotinic acetylcholine receptor (nAChR) antagonist mecamylamine (MEC) in a human laboratory setting."5.12Effects of acute abstinence, reinstatement, and mecamylamine on biochemical and behavioral measures of cigarette smoking in schizophrenia. ( Creeden, CL; George, TP; Jatlow, PI; Sacco, KA; Vessicchio, JC; Weinberger, AH, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuzmin, A1
Jerlhag, E1
Liljequist, S1
Engel, J1
Liu, X1
Caggiula, AR1
Yee, SK1
Nobuta, H1
Poland, RE1
Pechnick, RN1
Weinberger, AH1
Sacco, KA1
Creeden, CL1
Vessicchio, JC1
Jatlow, PI1
George, TP1
Henningfield, JE1

Reviews

1 review available for mecamylamine and Recrudescence

ArticleYear
Pharmacologic basis and treatment of cigarette smoking.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:12 Pt 2

    Topics: Animals; Chewing Gum; Compulsive Behavior; Conditioning, Operant; Drug Interactions; Humans; Mecamyl

1984

Trials

1 trial available for mecamylamine and Recrudescence

ArticleYear
Effects of acute abstinence, reinstatement, and mecamylamine on biochemical and behavioral measures of cigarette smoking in schizophrenia.
    Schizophrenia research, 2007, Volume: 91, Issue:1-3

    Topics: Acute Disease; Adult; Cotinine; Demography; Depression; Female; Humans; Male; Mecamylamine; Nicotine

2007

Other Studies

2 other studies available for mecamylamine and Recrudescence

ArticleYear
Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior.
    Psychopharmacology, 2009, Volume: 203, Issue:1

    Topics: Aconitine; Administration, Oral; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Central Ne

2009
Reinstatement of nicotine-seeking behavior by drug-associated stimuli after extinction in rats.
    Psychopharmacology, 2006, Volume: 184, Issue:3-4

    Topics: Animals; Association Learning; Cues; Disease Models, Animal; Extinction, Psychological; Male; Mecamy

2006