mecamylamine has been researched along with Peripheral Nerve Diseases in 2 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Physostigmine has different effects on allodynia and nociception, which suggests that different cholinergic (muscarinic) mechanisms may be involved in neuropathic and nociceptive pain." | 3.70 | Systemic physostigmine shows antiallodynic effects in neuropathic rats. ( Kalso, E; Kontinen, VK; Paananen, S; Pöyhiä, R; Xu, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pöyhiä, R | 1 |
| Xu, M | 1 |
| Kontinen, VK | 1 |
| Paananen, S | 1 |
| Kalso, E | 1 |
| Hentall, ID | 1 |
| Sagen, J | 1 |
2 other studies available for mecamylamine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Systemic physostigmine shows antiallodynic effects in neuropathic rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Atropine; Cholinergic Antagonists; Dose-Response Relationsh | 1999 |
Spinal CSF from rats with painful peripheral neuropathy evokes catecholamine release from chromaffin cells in vitro.
Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Cerebrospinal Fluid; Cerebrospina | 2000 |