mecamylamine has been researched along with Morphine Abuse in 10 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholinergic and anticholinergic agents were tested against the induction and expression of morphine dependence in rats." | 3.65 | Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat. ( Frederickson, RC; Pinsky, C, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taraschenko, OD | 1 |
| Panchal, V | 1 |
| Maisonneuve, IM | 2 |
| Glick, SD | 2 |
| Ramirez, RL | 1 |
| Livi, JM | 1 |
| Haghparast, A | 1 |
| Khani, A | 1 |
| Naderi, N | 1 |
| Alizadeh, AM | 1 |
| Motamedi, F | 1 |
| Zarrindast, MR | 1 |
| Farzin, D | 1 |
| Drawbaugh, RB | 1 |
| Lal, H | 1 |
| Frederickson, RC | 2 |
| Pinsky, C | 2 |
| Jhamandas, K | 2 |
| Sutak, M | 1 |
| Bell, S | 1 |
| Dickinson, G | 1 |
| Vazquez, AJ | 1 |
| Brase, DA | 1 |
| Tseng, LF | 1 |
| Loh, HH | 1 |
| Way, EL | 1 |
10 other studies available for mecamylamine and Morphine Abuse
| Article | Year |
|---|---|
Is antagonism of alpha3beta4 nicotinic receptors a strategy to reduce morphine dependence?
Topics: Acute Disease; Animals; Bupropion; Dextromethorphan; Drug Therapy, Combination; Female; Mecamylamine | 2005 |
18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats.
Topics: Animals; Behavior, Addictive; Conotoxins; Female; Habenula; Ibogaine; Mecamylamine; Mesencephalon; M | 2006 |
Repeated administration of nicotine attenuates the development of morphine tolerance and dependence in mice.
Topics: Analgesics, Opioid; Animals; Atropine; Dose-Response Relationship, Drug; Drug Tolerance; Ganglionic | 2008 |
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine | 1996 |
Effect of pharmacological interference with various neuropathways on blockade of morphine-withdrawal hypothermia by morphine and by conditional stimulus.
Topics: Animals; Benztropine; Conditioning, Classical; Cyproheptadine; Haloperidol; Humans; Hypothermia; Mal | 1976 |
Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat.
Topics: Animals; Atropine; Body Weight; Choline; Humans; Male; Mecamylamine; Morphine Dependence; Parasympat | 1975 |
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug | 1973 |
Modification of precipitated morphine and methadone abstinence in mice by acetylcholine antagonists.
Topics: Acetylcholine; Animals; Atropine; Drug Combinations; Humans; Mecamylamine; Methadone; Mice; Morphine | 1973 |
Morphine withdrawal syndrome responses to cholinergic antagonists and to a partial cholinergic agonist.
Topics: Animals; Atropine; Choline; Humans; Male; Mecamylamine; Morphine Dependence; Rats; Substance Withdra | 1973 |
Cholinergic modification of naloxone-induced jumping in morphine dependent mice.
Topics: Animals; Arecoline; Atropine; Behavior, Animal; Benztropine; Brain Chemistry; Dimethylphenylpiperazi | 1974 |