mecamylamine has been researched along with Lung Neoplasms in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The nicotine effect was antagonized by mecamylamine, an antagonist specific for neuronal nicotinic receptors." | 1.30 | Mechanisms of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells. ( Cattaneo, MG; D'atri, F; Vicentini, LM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, L | 1 |
| Li, L | 1 |
| Wang, W | 1 |
| Pan, Z | 1 |
| Zhou, Q | 1 |
| Wu, Z | 1 |
| Song, P | 1 |
| Sekhon, HS | 1 |
| Proskocil, B | 1 |
| Blusztajn, JK | 1 |
| Mark, GP | 1 |
| Spindel, ER | 1 |
| Cattaneo, MG | 2 |
| Codignola, A | 1 |
| Vicentini, LM | 2 |
| Clementi, F | 1 |
| Sher, E | 1 |
| D'atri, F | 1 |
4 other studies available for mecamylamine and Lung Neoplasms
| Article | Year |
|---|---|
Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dihydro-beta-Erythroidine; Humans; Hypoxia; Hypoxi | 2012 |
Synthesis of acetylcholine by lung cancer.
Topics: Acetylcholine; Animals; Atropine; Autocrine Communication; Carcinoma, Small Cell; Carrier Proteins; | 2003 |
Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma.
Topics: Carcinoma, Small Cell; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mecamylamine; Nicot | 1993 |
Mechanisms of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells.
Topics: Autocrine Communication; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Small Cel | 1997 |