mecamylamine has been researched along with Liver Cirrhosis in 1 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cigarette smoke (CS) may cause liver fibrosis but possible involved mechanisms are unclear." | 1.38 | Nicotine induces fibrogenic changes in human liver via nicotinic acetylcholine receptors expressed on hepatic stellate cells. ( Lin, C; McKee, C; Morgan, M; Mouralidarane, A; Oben, JA; Roskams, T; Soeda, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soeda, J | 1 |
| Morgan, M | 1 |
| McKee, C | 1 |
| Mouralidarane, A | 1 |
| Lin, C | 1 |
| Roskams, T | 1 |
| Oben, JA | 1 |
1 other study available for mecamylamine and Liver Cirrhosis
| Article | Year |
|---|---|
Nicotine induces fibrogenic changes in human liver via nicotinic acetylcholine receptors expressed on hepatic stellate cells.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Gene Expression; Hepatic Stellate Cells; Humans; Live | 2012 |