mecamylamine has been researched along with Ischemia in 3 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of topical or intraocular injection of mecamylamine, a nonspecific nAChR antagonist, or targeted deletion of α7- or α9-nAChRs on ischemia-induced retinal NV was determined by comparing the amount of retinal NV at P17 in these mice versus appropriate controls." | 3.85 | The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity. ( Abraham, S; Campochiaro, PA; Chadha, R; Cooke, JP; Fortmann, SD; Hackett, SF; Seidel, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hackett, SF | 1 |
| Seidel, C | 1 |
| Abraham, S | 1 |
| Chadha, R | 1 |
| Fortmann, SD | 1 |
| Campochiaro, PA | 1 |
| Cooke, JP | 2 |
| Heeschen, C | 1 |
| Weis, M | 1 |
| Aicher, A | 1 |
| Dimmeler, S | 1 |
| Wehman, HJ | 1 |
| Plantholt, BA | 1 |
| Lifshitz, F | 1 |
3 other studies available for mecamylamine and Ischemia
| Article | Year |
|---|---|
The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity.
Topics: Animals; Animals, Newborn; Cholinergic Agents; Disease Models, Animal; Ischemia; Mecamylamine; Mice; | 2017 |
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Carcinoma, Lewis Lung; Cell Division; Cells, Cultu | 2002 |
Microvillous anomalies induced by various conditions of stress in the small intestine of the rat.
Topics: Animals; Cytoplasm; Diarrhea; Epithelial Cells; Histological Techniques; Hypothermia; Injections, In | 1972 |