Page last updated: 2024-10-30

mecamylamine and Ischemia

mecamylamine has been researched along with Ischemia in 3 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" The effect of topical or intraocular injection of mecamylamine, a nonspecific nAChR antagonist, or targeted deletion of α7- or α9-nAChRs on ischemia-induced retinal NV was determined by comparing the amount of retinal NV at P17 in these mice versus appropriate controls."3.85The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity. ( Abraham, S; Campochiaro, PA; Chadha, R; Cooke, JP; Fortmann, SD; Hackett, SF; Seidel, C, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hackett, SF1
Seidel, C1
Abraham, S1
Chadha, R1
Fortmann, SD1
Campochiaro, PA1
Cooke, JP2
Heeschen, C1
Weis, M1
Aicher, A1
Dimmeler, S1
Wehman, HJ1
Plantholt, BA1
Lifshitz, F1

Other Studies

3 other studies available for mecamylamine and Ischemia

ArticleYear
The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity.
    Investigative ophthalmology & visual science, 2017, 02-01, Volume: 58, Issue:2

    Topics: Animals; Animals, Newborn; Cholinergic Agents; Disease Models, Animal; Ischemia; Mecamylamine; Mice;

2017
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors.
    The Journal of clinical investigation, 2002, Volume: 110, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Carcinoma, Lewis Lung; Cell Division; Cells, Cultu

2002
Microvillous anomalies induced by various conditions of stress in the small intestine of the rat.
    Experimental and molecular pathology, 1972, Volume: 17, Issue:3

    Topics: Animals; Cytoplasm; Diarrhea; Epithelial Cells; Histological Techniques; Hypothermia; Injections, In

1972