Page last updated: 2024-10-30

mecamylamine and Injuries, Spinal Cord

mecamylamine has been researched along with Injuries, Spinal Cord in 4 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (75.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dubé, GR	1
Kohlhaas, KL	1
Rueter, LE	1
Surowy, CS	1
Meyer, MD	1
Briggs, CA	1
Kaplan, PE	1
Nanninga, JB	1
Selye, H	1
Braddom, RL	1
Johnson, EW	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Pilot Study of Mecamylamine for Autonomic Dysreflexia Prophylaxis[NCT03914677]			Phase 4	5 participants (Anticipated)	Interventional	2019-06-13	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for mecamylamine and Injuries, Spinal Cord

Article	Year
Loss of functional neuronal nicotinic receptors in dorsal root ganglion neurons in a rat model of neuropathic pain. Neuroscience letters, 2005, Mar-07, Volume: 376, Issue:1 Topics: Acetylcholine; Animals; Azetidines; Cell Count; Cells, Cultured; Disease Models, Animal; Dose-Respon	2005
Reduction of bladder contractility after alpha-adrenergic blockade and after ganglionic blockade. Acta neurologica Scandinavica, 1979, Volume: 59, Issue:4 Topics: Adult; Atropine; Ganglia, Autonomic; Humans; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth;	1979
Protection by glucocorticoids against ganglioplegics. Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; Cold Temperature; Drug Antagonism; Fasting; Female; Formaldehy	1970
Mecamylamine in control of hyperreflexia. Archives of physical medicine and rehabilitation, 1969, Volume: 50, Issue:8 Topics: Adult; Autonomic Nervous System; Female; Humans; Male; Mecamylamine; Middle Aged; Reflex, Abnormal;	1969