mecamylamine has been researched along with Hypotension in 13 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with mecamylamine (50 micrograms; i." | 5.29 | Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. ( Savci, V; Ulus, IH, 1996) |
| " The reversal of hypotension by THA was greatly attenuated by administration of either prazosin, an alpha(1)-adrenoceptor antagonist (0." | 3.71 | Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine. ( Cavun, S; Gürün, MS; Savci, V; Ulus, IH, 2001) |
| "Pretreatment with mecamylamine (50 micrograms; i." | 1.29 | Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. ( Savci, V; Ulus, IH, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aydin, B | 1 |
| Guvenc, G | 1 |
| Altinbas, B | 1 |
| Niaz, N | 1 |
| Yalcin, M | 2 |
| Savci, V | 3 |
| Jochem, J | 1 |
| ARMAS CRUZ, R | 1 |
| ALVO, M | 1 |
| HARNECKER, J | 1 |
| SUNNAH, E | 1 |
| MELFI, M | 1 |
| BARBANO, G | 1 |
| BADOUAL, J | 1 |
| HUEGIN, W | 1 |
| BHARGAVA, KP | 1 |
| DHAWAN, KN | 1 |
| Baum, T | 1 |
| Sabin, C | 1 |
| Moran, RM | 1 |
| Ulus, IH | 2 |
| Haynes, JM | 1 |
| Hodgson, WC | 1 |
| Cooper, ME | 1 |
| Cavun, S | 1 |
| Gürün, MS | 1 |
| Lederis, K | 1 |
| Medaković, M | 1 |
| Carstens, E | 1 |
1 review available for mecamylamine and Hypotension
| Article | Year |
|---|---|
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
12 other studies available for mecamylamine and Hypotension
| Article | Year |
|---|---|
Modulation of nesfatin-1-induced cardiovascular effects by the central cholinergic system.
Topics: Acetylcholine; Animals; Blood Pressure; Brain; Calcium-Binding Proteins; Catecholamines; Cholinergic | 2018 |
Involvement of the cholinergic system in the central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hista | 2009 |
[Evaluation of a new hypotensive drug: mecamylamine in malignant hypertension].
Topics: Antihypertensive Agents; Autonomic Agents; Hypertension; Hypertension, Malignant; Hypotension; Mecam | 1957 |
[Clinical observations on a new hypotensive preparation with ganglioplegic action (mecamylamine hydrochloride)].
Topics: Autonomic Agents; Humans; Hypertension; Hypotension; Mecamylamine | 1957 |
[New hypotensive medications: guanethidine, alphamethyldopa, mecamylamine].
Topics: Antihypertensive Agents; Guanethidine; Humans; Hypotension; Mecamylamine; Methyldopa | 1963 |
DEPRESSION OF THE VASOMOTOR CENTRE BY MECAMYLAMINE, INDEPENDENT OF ITS GANGLION-BLOCKING ACTIVITY.
Topics: Acetylcholine; Animals; Cats; Central Nervous System; Depression; Depressive Disorder; Dogs; Ganglia | 1963 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd | 1981 |
Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Blood Pres | 1996 |
Rat amylin mediates a pressor response in the anaesthetised rat: implications for the association between hypertension and diabetes mellitus.
Topics: Amino Acid Sequence; Amyloid; Anesthesia, General; Angiotensin I; Animals; Blood Pressure; Calcitoni | 1997 |
Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Intravenous; Animals; Antidiuretic Hormone Receptor Antag | 2001 |
Pharmacological observations on the hypotensive action of extracts of teleost fish Urophyses (urotensin I) in the rat.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Blood Pressure; Bradykinin; Diphenhydramine; Epine | 1974 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |