mecamylamine has been researched along with Hypertension in 86 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both the antinociceptive and toxic effects (convulsions and hypertension) were abolished by pretreatment with the brain penetrant neuronal nAChR antagonist mecamylamine (1 mg/kg s." | 3.70 | Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats. ( Boyce, S; Hill, RG; Rupniak, NMJ; Russell, MGN; Shepheard, SL; Webb, JK, 2000) |
| "Mecamylamine hydrochloride was initially developed for its ganglion-blocking activity and has been marketed as an antihypertensive agent in the United States for >40 years." | 2.41 | Mecamylamine: new therapeutic uses and toxicity/risk profile. ( George, TP; Sanberg, PR; Shytle, RD; Young, JM, 2001) |
| "Obesity is a major risk factor for hypertension." | 1.38 | Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity. ( Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML, 2012) |
| " isoproterenol tachycardia dose-response curves by dose ratios of 5, 18, and 90 in sham rabbits, respectively, and 5, 11, and 23 in wrap rabbits, respectively, indicating significant cardiac beta 1-adrenoceptor antagonism." | 1.28 | Relationship between the sympatholytic action of nebivolol and hypotension. ( Angus, JA; Coles, P; Cox, H; Eisenhofer, G; Ward, JE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (91.86) | 18.7374 |
| 1990's | 3 (3.49) | 18.2507 |
| 2000's | 3 (3.49) | 29.6817 |
| 2010's | 1 (1.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, Y | 1 |
| Shimoji, Y | 1 |
| Fujita, H | 1 |
| Nishino, H | 1 |
| Mizuno, H | 1 |
| Kobayashi, S | 1 |
| Kumakura, S | 1 |
| Belin de Chantemèle, EJ | 1 |
| Ali, MI | 1 |
| Mintz, JD | 1 |
| Rainey, WE | 1 |
| Tremblay, ML | 1 |
| Fulton, DJ | 1 |
| Stepp, DW | 1 |
| MOYER, JH | 2 |
| FORD, R | 1 |
| DENNIS, E | 2 |
| HANDLEY, CA | 1 |
| FREIS, ED | 1 |
| WILSON, IM | 1 |
| COSSIO, P | 2 |
| ELIZALDE, A | 2 |
| WERKO, L | 2 |
| MCQUEEN, EG | 2 |
| SMIRK, FH | 2 |
| MCCORMICK, WF | 1 |
| GRANT, AP | 1 |
| BOYD, JS | 1 |
| VON AHN, B | 1 |
| BIDOGGIA, H | 1 |
| BOVONE, H | 1 |
| REAL, AP | 1 |
| PERRY, HM | 2 |
| SCHROEDER, HA | 2 |
| MOYER, J | 1 |
| HEIDER, C | 1 |
| COTTIER, PT | 1 |
| WELLER, JM | 1 |
| HOOBLER, SW | 1 |
| BERCONSKY, I | 1 |
| NIJENSOHN, CM | 1 |
| LITVAK BRUNO, P | 1 |
| GIORDANO, C | 1 |
| RICCIARDI, S | 1 |
| ORIENTE, P | 1 |
| DENNIS, EW | 1 |
| FORD, RV | 1 |
| HERSHBERGER, RL | 1 |
| KITCHIN, A | 1 |
| LOWTHER, CP | 1 |
| TURNER, RW | 2 |
| ARMAS CRUZ, R | 1 |
| ALVO, M | 1 |
| HARNECKER, J | 1 |
| SUNNAH, E | 1 |
| MELFI, M | 1 |
| MILNE, MD | 1 |
| ROWE, GG | 1 |
| SOMERS, K | 2 |
| MUEHRCKE, RC | 1 |
| CRAWFORD, MA | 1 |
| BARBANO, G | 1 |
| FRIIS, T | 1 |
| CHRISTENSEN, LK | 1 |
| MANZINI, E | 1 |
| MORINI, A | 1 |
| PALTRINIERI, C | 1 |
| DATEY, KK | 1 |
| JOSHI, NK | 1 |
| BIANCHESSI, M | 1 |
| MAUCH, HP | 1 |
| UNGER, AM | 1 |
| PORTER, RR | 1 |
| MARCHETTI, G | 1 |
| NAVA, S | 1 |
| TARTARA, A | 1 |
| LUCCHELLI, P | 1 |
| AGAR, H | 1 |
| BARRETT, CT | 1 |
| EXLEY, KA | 1 |
| BARNETT, AJ | 1 |
| MARSHALL, RJ | 1 |
| BOYD, LJ | 1 |
| HUPPERT, VF | 1 |
| MULINOS, MG | 1 |
| HAMMER, H | 1 |
| SEARS, HT | 1 |
| SNOW, PJ | 1 |
| HOUSTON, IB | 1 |
| VITELLI, A | 1 |
| MOLINARO, R | 1 |
| GRANDIS, C | 1 |
| SIRACUSA, F | 1 |
| MUNSTER, AM | 1 |
| BAUER, GE | 1 |
| EDWARDS, AW | 1 |
| RITCHIE, FL | 1 |
| WHYTE, HM | 1 |
| BOUSVAROS, GA | 1 |
| GALARRAGA, J | 1 |
| COZZOLINO, ER | 1 |
| SMITH, TH | 1 |
| ROSSI, GV | 1 |
| MEDVEDOWSKY, JL | 1 |
| SACCO, JJ | 1 |
| PATEL, BJ | 1 |
| JOSHI, HD | 1 |
| FIFE, R | 1 |
| MORAN, F | 1 |
| PRINEAS, J | 1 |
| GASCARD, E | 1 |
| CASANOVA, P | 1 |
| GIRALDI, A | 2 |
| MAINIERI, L | 1 |
| CHERIE LIGNIERE, E | 1 |
| FOSS, PO | 1 |
| RECORDIER, M | 1 |
| CAMATTE, R | 1 |
| BINE, PL | 1 |
| ROSENBLOOM, SE | 1 |
| SHAPERA, RP | 1 |
| GOLDBLOOM, RS | 1 |
| SHEPS, MC | 1 |
| SHAPIRO, AP | 1 |
| VERCILLO, L | 1 |
| VIDRIO, H | 4 |
| PARDO, EG | 5 |
| SAINANI, GS | 1 |
| NAWAZ, M | 1 |
| HUEGIN, W | 1 |
| SJOERDSMA, A | 1 |
| MATHISEN, HS | 1 |
| VARGAS, R | 2 |
| CHIRONE, E | 1 |
| MILLIGAN, J | 1 |
| URANGAIMAZ, FA | 2 |
| TONNELIER, E | 1 |
| KLAUER, D | 1 |
| CHEKERDEMIAN, M | 1 |
| BECKWITH, JR | 1 |
| CAMP, JL | 1 |
| MOSCA, A | 1 |
| MEIRING, PD | 1 |
| IANNONE, D | 1 |
| FRANCESE, G | 1 |
| MARONDE, RF | 1 |
| BARBOUR, B | 1 |
| FRASHER, W | 1 |
| Bello, CT | 1 |
| Sevy, RW | 1 |
| Harakal, C | 1 |
| Hillyer, PN | 1 |
| Khan, IM | 1 |
| Printz, MP | 1 |
| Yaksh, TL | 1 |
| Taylor, P | 1 |
| Haynes, JM | 1 |
| Hodgson, WC | 1 |
| Cooper, ME | 1 |
| Boyce, S | 1 |
| Webb, JK | 1 |
| Shepheard, SL | 1 |
| Russell, MGN | 1 |
| Hill, RG | 1 |
| Rupniak, NMJ | 1 |
| Young, JM | 1 |
| Shytle, RD | 1 |
| Sanberg, PR | 1 |
| George, TP | 1 |
| Ueno, K | 1 |
| Togashi, H | 1 |
| Matsumoto, M | 1 |
| Ohashi, S | 1 |
| Saito, H | 1 |
| Yoshioka, M | 1 |
| Rick, JH | 1 |
| Oparil, S | 1 |
| Buckingham, RE | 1 |
| Hamilton, TC | 1 |
| Robson, D | 1 |
| Darke, AC | 1 |
| Melnyk, J | 1 |
| Nair, PG | 1 |
| Gaskell, P | 1 |
| Cosnier, D | 2 |
| Duchene-Marullaz, P | 1 |
| Grimal, J | 1 |
| Rispat, G | 2 |
| Streichenberger, G | 2 |
| Labrid, C | 1 |
| Ward, JE | 1 |
| Coles, P | 1 |
| Cox, H | 1 |
| Eisenhofer, G | 1 |
| Angus, JA | 1 |
| Kincaid-Smith, P | 1 |
| Fang, P | 1 |
| Laver, MC | 1 |
| Brod, J | 1 |
| Carstens, E | 1 |
| Griffith, ER | 1 |
| Taylor, N | 1 |
| DeLateur, BJ | 1 |
| Lehmann, JF | 1 |
| López, J | 1 |
| Le Lorie, J | 1 |
| Willard, PW | 1 |
| Beckhelm, GA | 1 |
| Rosenblum, I | 1 |
| Rosenblum, G | 1 |
| Dalla Volta, S | 1 |
| Catanzaro, FJ | 1 |
| Moore-Jones, D | 1 |
| Camel, GH | 1 |
4 reviews available for mecamylamine and Hypertension
| Article | Year |
|---|---|
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
[MALIGNANT HYPERTENSION].
Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricte | 1964 |
Mecamylamine: new therapeutic uses and toxicity/risk profile.
Topics: Animals; Antihypertensive Agents; Area Under Curve; Autonomic Dysreflexia; Central Nervous System; C | 2001 |
[Pathogenesis of essential hypertension with special reference to therapy].
Topics: Adolescent; Adrenal Glands; Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Diazepam; Diu | 1971 |
1 trial available for mecamylamine and Hypertension
| Article | Year |
|---|---|
A new look at the treatment of severe hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Clinica | 1973 |
81 other studies available for mecamylamine and Hypertension
| Article | Year |
|---|---|
Studies on cardiovascular agents. 6. Synthesis and coronary vasodilating and antihypertensive activities of 1,2,4-triazolo[1,5-a]pyrimidines fused to heterocyclic systems.
Topics: Animals; Antihypertensive Agents; Coronary Circulation; Coronary Vessels; Dogs; Female; Guinea Pigs; | 1980 |
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity.
Topics: Adrenergic alpha-1 Receptor Agonists; Albuminuria; Aldosterone; Animals; Blood Pressure; Dose-Respon | 2012 |
Laboratory and clinical observations on mecamylamine as a hypotensive agent.
Topics: Antihypertensive Agents; Camphor; Hypertension; Laboratories; Mecamylamine | 1955 |
Mecamylamine, a new, orally effective, hypotensive agent; experimental and clinical evaluation.
Topics: Antihypertensive Agents; Camphor; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Studies on the use of mecamylamine in 10 cases of moderate and severe hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine ileus as a surgical emergency.
Topics: Autonomic Agents; Hypertension; Ileus; Intestinal Obstruction; Mecamylamine | 1957 |
[Mecamylamine therapy of hypertension; preliminary report].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Treatment of arterial hypertension with mecamylamine].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
[Mecamylamine in hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Neurological manifestations after antihypertensive therapy with mecamylamine.
Topics: Antihypertensive Agents; Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine (inversine) in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Evaluation of mecamylamine in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Treatment of severe arterial hypertension with 2 new ganglionic blocking agents administered orally; ecolid & inversine].
Topics: Autonomic Agents; Chlorisondamine; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Use of mecamylamine in the treatment of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine; a ganglion-blocking drug for treating hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine; Monitoring, Physiologic; Professional Practice | 1957 |
[Evaluation of a new hypotensive drug: mecamylamine in malignant hypertension].
Topics: Antihypertensive Agents; Autonomic Agents; Hypertension; Hypertension, Malignant; Hypotension; Mecam | 1957 |
Observations on the pharmacology of mecamylamine.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Clinical observations on a new hypotensive preparation with ganglioplegic action (mecamylamine hydrochloride)].
Topics: Autonomic Agents; Humans; Hypertension; Hypotension; Mecamylamine | 1957 |
[Myocardial infarct caused by mecamylamine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine; Myocardial Infarction | 1957 |
[Use of mecamylamine in the treatment of arterial hypertension].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1957 |
Mecamylamine hydrochloride in the treatment of hypertension.
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1958 |
[Mecamylamine combined with reserpine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine; Reserpine | 1957 |
Mecamylamine-reserpine; results of treatment in severe hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine; Reserpine | 1958 |
[Experimental & clinical observation on the activity of a new synthetic ganglioplegic: mecamylamine (3-methylaminoisocamphane hydrochloride)].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1958 |
[Clinical notes on the use of mecamylamine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1958 |
Experiences with mecamylamine in hypertensive complications of pregnancy.
Topics: Autonomic Agents; Eclampsia; Female; Humans; Hypertension; Mecamylamine; Pre-Eclampsia; Pregnancy; P | 1958 |
Treatment of hypertension with a combination of chlorothiazide and mecamylamine.
Topics: Acetazolamide; Autonomic Agents; Chlorothiazide; Hypertension; Mecamylamine | 1958 |
Meprobamate in treatment of hypertension; its effects alone and in combination with mecamylamine.
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine; Meprobamate | 1959 |
Treatment of hypertension with pentolinium and mecamylamine.
Topics: Autonomic Agents; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central; Pent | 1959 |
Mecamylamine and reserpine in the management of severe and malignant hypertension in Uganda.
Topics: Autonomic Agents; Disease Management; Hypertension; Hypertension, Malignant; Mecamylamine; Reserpine | 1959 |
[Clinical & functional data on the effects of a mecamylamine-reserpine combination in hypertension].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine; Reserpine | 1959 |
The side effects of mecamylamine hydrochloride: a review of 50 cases.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1961 |
Mecamylamine in the treatment of hypertension.
Topics: Antihypertensive Agents; Hypertension; Mecamylamine | 1959 |
Mecamylamine and chlorothiazide in the treatment of hypertension in out-patients.
Topics: Autonomic Agents; Autonomic Nervous System; Chlorothiazide; Hypertension; Mecamylamine; Outpatients | 1961 |
[Treatment of hypertension in pregnancy with mecamylamine and chlorothiazide].
Topics: Autonomic Agents; Autonomic Nervous System; Chlorothiazide; Female; Hypertension; Mecamylamine; Preg | 1961 |
The effect of reserpine and mecamylamine on experimental atheromatosis in the normotensive and hypertensive rat.
Topics: Animals; Arteriosclerosis; Autonomic Agents; Blood Pressure; Cholesterol; Hypertension; Mecamylamine | 1962 |
[Clinical trials of inversine (mecamylamine) in arterial hypertension].
Topics: Hypertension; Mecamylamine | 1963 |
Clinical trial of mecamylamine on patients with hypertension.
Topics: Hypertension; Mecamylamine | 1963 |
Treatment of hypertension in out-patients: mecamylamine, bretylium and guanethidine.
Topics: Bretylium Compounds; Guanethidine; Hypertension; Mecamylamine; Outpatients | 1962 |
[Results of therapeutic use of mecamylamine (Inversine) in the treatment of arterial hypertension].
Topics: Hypertension; Mecamylamine | 1962 |
[The renal hemodynamics of hypertensive subjects treated with mecamylamine associated with reserpine and dihydrochlorothiazide].
Topics: Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Function Tests; Mecamylamine | 1963 |
[Medical treatment of essential hypertension. 4-year case material].
Topics: Chlorothiazide; Essential Hypertension; Humans; Hydralazine; Hypertension; Mecamylamine; Reserpine | 1962 |
[Results of the treatment of arterial hypertension with Mecamylamine].
Topics: Hypertension; Mecamylamine | 1963 |
Technic of controlled drug assay. III. Comparison of guanethidine, mecamylamine and a placebo in the hypertensive patient.
Topics: Guanethidine; Humans; Hypertension; Mecamylamine | 1963 |
[Influence of mecamylamine and of its combination with 1,4-dihydrazinophthalazine or reserpine on renal hemodynamics in patients with arterial hypertension].
Topics: Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Kidney; Mecamylamine; Renal Artery; Res | 1962 |
Development of hypertension during chronic mecamylamine administration in dogs.
Topics: Animals; Dogs; Drug Tolerance; Hypertension; Mecamylamine | 1963 |
TREATMENT OF HYPERTENSION WITH GUANETHIDINE.
Topics: Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Mecamylamine; Toxicology | 1963 |
CHEMOTHERAPY OF HYPERTENSION: YESTERDAY--TODAY--TOMORROW.
Topics: Alkaloids; Amines; Antihypertensive Agents; Chlorisondamine; Chlorothiazide; Dihydroxyphenylalanine; | 1963 |
[DRUG THERAPY OF HIGH BLOOD PRESSURE IN THE PAST, PRESENT AND FUTURE].
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hyperten | 1963 |
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL MODELS OF ARTERIAL HYPERTENSION].
Topics: Animals; Chlorisondamine; Classification; Cortisone; Dogs; Ganglionic Blockers; Hydrochlorothiazide; | 1964 |
HYPERTENSION AND ITS COMPLICATIONS. 2.
Topics: Amobarbital; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cold Temperature | 1964 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
SUSTAINED HYPERTENSION IN DOGS FOLLOWING CHRONIC ADMINISTRATION OF GANGLIONIC BLOCKING AGENTS.
Topics: Animals; Blood Pressure; Chlorisondamine; Dogs; Ganglionic Blockers; Hydrochlorothiazide; Hypertensi | 1964 |
RECENT TRENDS IN THE MEDICAL TREATMENT OF HYPERTENSION.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Hydralazine; Hypertension; Mecamylamine; Methyldop | 1964 |
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulo | 1965 |
[Treatment of hypertension with reserpine-mecamylamine (cesatin)].
Topics: Hypertension; Mecamylamine; Reserpine | 1959 |
Intravenous mecamylamine (inversine) as a means of determining the effective oral dosage.
Topics: Administration, Intravenous; Humans; Hypertension; Mecamylamine | 1960 |
Relationship between clinical severity of disease and hemodynamic patterns in essential hypertension.
Topics: Adolescent; Adult; Aged; Cardiac Output; Female; Follow-Up Studies; Guanethidine; Hemodynamics; Huma | 1967 |
Further study of the sustained hypertension produced by chronic administration of mecamylamine.
Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Mecamyla | 1967 |
Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension.
Topics: Aconitine; Alkaloids; Animals; Azocines; Blood Pressure; Dihydro-beta-Erythroidine; Dose-Response Re | 1994 |
Rat amylin mediates a pressor response in the anaesthetised rat: implications for the association between hypertension and diabetes mellitus.
Topics: Amino Acid Sequence; Amyloid; Anesthesia, General; Angiotensin I; Animals; Blood Pressure; Calcitoni | 1997 |
Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Behavior, Animal; Body Temperature; Bridged Bicyclo C | 2000 |
Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention Deficit Disorder with Hyperactivity; Beh | 2002 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertensio | 1977 |
Studies on the cardiovascular effects of pindolol in DOCA/saline hypertensive rats.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Blood Pressure; Desoxycorticosterone; Dr | 1977 |
Experimental aldosterone hypertension in the rat.
Topics: Aldosterone; Animals; Blood Pressure; Chlorisondamine; Desoxycorticosterone; Drug Interactions; Etha | 1977 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Dogs; Dose-Response R | 1975 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis.
Topics: Animals; Antihypertensive Agents; Aorta; Autonomic Nervous System; Blood Pressure; Cerebrovascular C | 1975 |
Relationship between the sympatholytic action of nebivolol and hypotension.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Dose-Res | 1992 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Orthostatic hypertension following brain trauma: report of a case.
Topics: Adolescent; Brain Edema; Brain Injuries; Follow-Up Studies; Guanethidine; Hematoma, Subdural; Humans | 1971 |
[Recent progress in the knowledge of arterial hypertension. VII. Acute effects of antihypertensive drugs on kidney function].
Topics: Acute Disease; Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertensi | 1967 |
Differential effect of hypotensive drugs on renal and steroid hypertensive rats.
Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Desoxycorticosterone; Guan | 1968 |
Cardiovascular responses to cyclohexylamine.
Topics: Amines; Animals; Blood Pressure; Bradycardia; Cardiovascular System; Cats; Cocaine; Cyclohexanes; Fe | 1968 |
[Medical therapy of arterial hypertension].
Topics: Antihypertensive Agents; Arteries; Diuretics; Guanethidine; Humans; Hydrazines; Hypertension; Mecamy | 1968 |
Studies on the control of hypertension. 8. Mortality, morbidity, and remissions during twelve years of intensive therapy.
Topics: Chlorisondamine; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Mecamylam | 1966 |