mecamylamine has been researched along with Hypercapnia in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicotine exposure is associated with numerous neurodevelopmental aberrations, including impairment of the neuroventilatory response to hypercapnia in bullfrog tadpoles and mouse neonates following prolonged developmental exposure." | 3.76 | Nicotine elicits a developmentally dependent depression in bullfrog neuroventilatory response to CO(2). ( Brundage, CM; Cartagena, CM; Potter, EA; Taylor, BE, 2010) |
| "Cholinergic neuronal influences on the function of male rat's hypothalamo-hypophyseal-adrenocortical (HHA) system both during basal and stressful situations (hypoxia and hypercapnia) were investigated using a cholinergic agonist (eserine) and antagonists (atropine, methyl atropine, mecamylamine and 4-(1-naphthylvinyl) pyridine)." | 3.65 | Actions of cholinergic agonist and antagonists on the adrenocortical response of basal, hypoxic, and hypercapnic rats. ( Marotta, SF; Sithichoke, N, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furuya, WI | 1 |
| Bassi, M | 1 |
| Menani, JV | 1 |
| Colombari, E | 1 |
| Zoccal, DB | 1 |
| Colombari, DSA | 1 |
| Brundage, CM | 1 |
| Cartagena, CM | 1 |
| Potter, EA | 1 |
| Taylor, BE | 1 |
| Marotta, SF | 2 |
| Sithichoke, N | 2 |
4 other studies available for mecamylamine and Hypercapnia
| Article | Year |
|---|---|
Modulation of hypercapnic respiratory response by cholinergic transmission in the commissural nucleus of the solitary tract.
Topics: Animals; Atropine; Cholinergic Neurons; Hypercapnia; Hypoglossal Nerve; Male; Mecamylamine; Muscarin | 2020 |
Nicotine elicits a developmentally dependent depression in bullfrog neuroventilatory response to CO(2).
Topics: Age Factors; Analysis of Variance; Animals; Brain Stem; Carbon Dioxide; Dose-Response Relationship, | 2010 |
Actions of cholinergic agonist and antagonists on the adrenocortical response of basal, hypoxic, and hypercapnic rats.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Atropine; Atropine Derivatives | 1977 |
Cholinergic influences on hypothalamic-pituitary-adrenocortical activity of stressed rats: an approach utilizing agonists and antagonists.
Topics: Acoustic Stimulation; Animals; Atropine; Corticosterone; Dexamethasone; Hypercapnia; Hypothalamo-Hyp | 1978 |