mecamylamine has been researched along with Hyperactivity, Motor in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mecamylamine pretreatment attenuated the hyperactivity and sensitization produced by repeated, but not acute, ephedrine (10 mg/kg) injection." | 1.33 | Mecamylamine attenuates ephedrine-induced hyperactivity in rats. ( Miller, DK; Segert, IL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trigo, JM | 1 |
| Zimmer, A | 1 |
| Maldonado, R | 1 |
| Miller, DK | 1 |
| Segert, IL | 1 |
| Hassel, B | 1 |
| O'Neill, MF | 1 |
| Fernández, AG | 1 |
| Gristwood, RW | 1 |
| Palacios, JM | 1 |
4 other studies available for mecamylamine and Hyperactivity, Motor
| Article | Year |
|---|---|
Nicotine anxiogenic and rewarding effects are decreased in mice lacking beta-endorphin.
Topics: Animals; Anxiety; beta-Endorphin; Conditioning, Classical; Crosses, Genetic; Exploratory Behavior; F | 2009 |
Mecamylamine attenuates ephedrine-induced hyperactivity in rats.
Topics: Animals; Ephedrine; Hyperkinesis; Male; Mecamylamine; Rats; Rats, Sprague-Dawley | 2005 |
Nicotinic mechanisms contribute to soman-induced symptoms and lethality.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Behavior, Animal; Chemical Warfare Agents; Dise | 2006 |
Mecamylamine reverses physostigmine-induced attenuation of scopolamine-induced hyperactivity.
Topics: Animals; Hexamethonium; Hyperkinesis; Male; Mecamylamine; Motor Activity; Muscarinic Antagonists; Ni | 1994 |