mecamylamine has been researched along with Hemorrhagic Shock in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an experimental model of hemorrhagic shock resulting in the death of almost all rats within 20-30 min, centrally active cholinomimetic drugs are reported to induce a prompt, sustained and dose-dependent improvement in blood pressure and survival rate claimed to be due to nicotinic, but not muscarinic actions." | 5.29 | Reversal of hemorrhagic shock in rats by oxotremorine: the role of muscarinic and nicotinic receptors, and AV3V region. ( Aslan, N; Gören, Z; Oktay, S; Onat, F; Ozkutlu, U, 1994) |
| " The reversal of hypotension by THA was greatly attenuated by administration of either prazosin, an alpha(1)-adrenoceptor antagonist (0." | 3.71 | Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine. ( Cavun, S; Gürün, MS; Savci, V; Ulus, IH, 2001) |
| "In an experimental model of hemorrhagic shock resulting in the death of almost all rats within 20-30 min, centrally active cholinomimetic drugs are reported to induce a prompt, sustained and dose-dependent improvement in blood pressure and survival rate claimed to be due to nicotinic, but not muscarinic actions." | 1.29 | Reversal of hemorrhagic shock in rats by oxotremorine: the role of muscarinic and nicotinic receptors, and AV3V region. ( Aslan, N; Gören, Z; Oktay, S; Onat, F; Ozkutlu, U, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yalcin, M | 1 |
| Savci, V | 2 |
| Jochem, J | 1 |
| Mathis, KW | 1 |
| Sulzer, J | 1 |
| Molina, PE | 1 |
| Onat, F | 1 |
| Aslan, N | 1 |
| Gören, Z | 1 |
| Ozkutlu, U | 1 |
| Oktay, S | 1 |
| Cavun, S | 1 |
| Gürün, MS | 1 |
| Ulus, IH | 1 |
4 other studies available for mecamylamine and Hemorrhagic Shock
| Article | Year |
|---|---|
Involvement of the cholinergic system in the central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hista | 2009 |
Systemic administration of a centrally acting acetylcholinesterase inhibitor improves outcome from hemorrhagic shock during acute alcohol intoxication.
Topics: Alcoholic Intoxication; Animals; Atropine; Cholinesterase Inhibitors; Male; Mecamylamine; Physostigm | 2010 |
Reversal of hemorrhagic shock in rats by oxotremorine: the role of muscarinic and nicotinic receptors, and AV3V region.
Topics: Animals; Atropine; Blood Pressure; Cerebral Ventricles; Female; Injections, Intravenous; Injections, | 1994 |
Reversal of Haemorrhagic Shock in Rats by Tetrahydroaminoacridine.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Intravenous; Animals; Antidiuretic Hormone Receptor Antag | 2001 |