mecamylamine has been researched along with Genetic Predisposition in 2 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because nicotine dependence (ND) is highly comorbid with schizophrenia and other substance abuse, we examined the association of HINT1 with ND." | 1.37 | Association of the histidine-triad nucleotide-binding protein-1 (HINT1) gene variants with nicotine dependence. ( Aggen, SH; Chen, J; Chen, Q; Chen, X; Jackson, KJ; Kendler, KS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dash, B | 1 |
| Lukas, RJ | 1 |
| Li, MD | 1 |
| Jackson, KJ | 1 |
| Chen, Q | 1 |
| Chen, J | 1 |
| Aggen, SH | 1 |
| Kendler, KS | 1 |
| Chen, X | 1 |
2 other studies available for mecamylamine and Genetic Predisposition
| Article | Year |
|---|---|
A signal peptide missense mutation associated with nicotine dependence alters α2*-nicotinic acetylcholine receptor function.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Genetic Predisposition to Disease; Humans; Mecamylamine | 2014 |
Association of the histidine-triad nucleotide-binding protein-1 (HINT1) gene variants with nicotine dependence.
Topics: Adolescent; Adult; Aged; Animals; Autopsy; Brain; Gene Frequency; Genetic Predisposition to Disease; | 2011 |