Page last updated: 2024-10-30

mecamylamine and Facial Pain

mecamylamine has been researched along with Facial Pain in 2 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Research Excerpts

ExcerptRelevanceReference
" Thus, the purpose of the present studies was to evaluate whether the neuronal nicotinic receptor agonist epibatidine possesses antihyperalgesic activity in the formalin model of facial pain."7.71Antihyperalgesic activity of epibatidine in the formalin model of facial pain. ( Clark, TM; Flores, CM; Gilbert, SD, 2001)
" Thus, the purpose of the present studies was to evaluate whether the neuronal nicotinic receptor agonist epibatidine possesses antihyperalgesic activity in the formalin model of facial pain."3.71Antihyperalgesic activity of epibatidine in the formalin model of facial pain. ( Clark, TM; Flores, CM; Gilbert, SD, 2001)
"Orofacial pain was induced by subcutaneous injection of a diluted formalin solution (50μl, 1."1.42The role of nicotinic acetylcholine and opioid systems of the ventral orbital cortex in modulation of formalin-induced orofacial pain in rats. ( Farshid, AA; Tamaddonfard, E; Yousofizadeh, S, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yousofizadeh, S1
Tamaddonfard, E1
Farshid, AA1
Gilbert, SD1
Clark, TM1
Flores, CM1

Other Studies

2 other studies available for mecamylamine and Facial Pain

ArticleYear
The role of nicotinic acetylcholine and opioid systems of the ventral orbital cortex in modulation of formalin-induced orofacial pain in rats.
    European journal of pharmacology, 2015, Jul-05, Volume: 758

    Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Therapy, Combination; Fac

2015
Antihyperalgesic activity of epibatidine in the formalin model of facial pain.
    Pain, 2001, Volume: 89, Issue:2-3

    Topics: Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationsh

2001