mecamylamine has been researched along with Diabetes Mellitus, Type 1 in 1 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using the multiple low-dose streptozotocin (MLD-STZ) model of experimental autoimmune diabetes, we previously reported that pretreatment with a specific acetylcholinesterase inhibitor (AChEI), paraoxon, prevented the development of hyperglycemia in C57BL/6 mice." | 3.91 | Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes. ( Al-Mansori, A; Al-Ramadi, BK; Bashir, G; Fernández-Cabezudo, MJ; George, JA; Lorke, DE; Mohamed, YA; Petroianu, G; Qureshi, MM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández-Cabezudo, MJ | 1 |
| George, JA | 1 |
| Bashir, G | 1 |
| Mohamed, YA | 1 |
| Al-Mansori, A | 1 |
| Qureshi, MM | 1 |
| Lorke, DE | 1 |
| Petroianu, G | 1 |
| Al-Ramadi, BK | 1 |
1 other study available for mecamylamine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes.
Topics: Acetylcholinesterase; Animals; Atropine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; | 2019 |