mecamylamine has been researched along with Body Weight in 14 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " MEC prevented CRS-induced depressive-like behavior via increasing sucrose preference, body weight, and forced swim test (FST) struggling and swimming while reducing immobility in FST and hypothalamic-pituitary-adrenal (HPA) axis hyperactivity (adrenal gland weight and serum corticosterone)." | 3.81 | Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters. ( Aboul-Fotouh, S, 2015) |
| " Chronic intermittent non-contingent, second-hand exposure to cigarette smoke or e-cig vapour led to similar brain cotinine and nicotine levels, similar urine cotinine levels and the similar up-regulation of α4β2 nicotinic acetylcholine receptors in different brain areas, but had different effects on body weight, food intake, and the signs of mecamylamine-precipitated and spontaneous withdrawal episodic memory and emotional responses." | 3.81 | Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice. ( Braida, D; Cannazza, G; Castellana, CN; Clementi, F; Fasoli, F; Gallesi, G; Gotti, C; Lucini, V; Moretti, M; Mucchietto, V; Ponzoni, L; Sala, M; Zoli, M, 2015) |
| "The symptom of "diminished interest or pleasure" in rewarding stimuli is an affective symptom of nicotine and amphetamine withdrawal, and a core symptom of depression." | 3.71 | Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. ( Harrison, AA; Liem, YT; Markou, A, 2001) |
| "Neonatal mice were administered nicotine (66 microg (-)-nicotine base/kg body weight (bw) s." | 3.70 | Neonatal nicotine administration influences ethanol-induced behaviors. ( Ankarberg, E; Archer, T; Eriksson, P; Fredriksson, A; Palomo, T, 2000) |
| "Cholinergic and anticholinergic agents were tested against the induction and expression of morphine dependence in rats." | 3.65 | Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat. ( Frederickson, RC; Pinsky, C, 1975) |
| "Nicotine dependence was induced via osmotic minipump in adolescent rats (releasing 22." | 1.33 | Withdrawal from chronic nicotine in adolescent and adult rats. ( Spear, LP; Wilmouth, CE, 2006) |
| "The nicotine abstinence was mild and protracted, lasting more than 92 h." | 1.30 | Nicotine abstinence in the mouse. ( Hadjiconstantinou, M; Isola, R; Neff, NH; Vogelsberg, V; Wemlinger, TA, 1999) |
| "Pretreatment with mecamylamine caused a decline in DNA synthesis by itself, but nevertheless prevented the effect of chlorpyrifos." | 1.29 | Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. ( Seidler, FJ; Slotkin, TA; Whitney, KD, 1995) |
| " On each day, the baroreflex, reactive hyperaemic responses and hindquarter vascular dose-response curves to i." | 1.29 | Baroreflex resetting but no vascular tolerance in response to transdermal glyceryl trinitrate in conscious rabbits. ( Angus, JA; Serone, AP; Wright, CE, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aboul-Fotouh, S | 1 |
| Ponzoni, L | 1 |
| Moretti, M | 1 |
| Sala, M | 1 |
| Fasoli, F | 1 |
| Mucchietto, V | 1 |
| Lucini, V | 1 |
| Cannazza, G | 1 |
| Gallesi, G | 1 |
| Castellana, CN | 1 |
| Clementi, F | 1 |
| Zoli, M | 1 |
| Gotti, C | 1 |
| Braida, D | 1 |
| White, CW | 1 |
| Short, JL | 1 |
| Haynes, JM | 1 |
| Matsui, M | 1 |
| Ventura, S | 1 |
| Taylor, GT | 1 |
| Bassi, CJ | 1 |
| Weiss, J | 1 |
| Wilmouth, CE | 1 |
| Spear, LP | 1 |
| Whitney, KD | 1 |
| Seidler, FJ | 1 |
| Slotkin, TA | 1 |
| Serone, AP | 1 |
| Angus, JA | 1 |
| Wright, CE | 1 |
| Isola, R | 1 |
| Vogelsberg, V | 1 |
| Wemlinger, TA | 1 |
| Neff, NH | 1 |
| Hadjiconstantinou, M | 1 |
| Hayden, UL | 1 |
| Carey, HV | 1 |
| Fredriksson, A | 1 |
| Eriksson, P | 1 |
| Ankarberg, E | 1 |
| Palomo, T | 1 |
| Archer, T | 1 |
| Harrison, AA | 1 |
| Liem, YT | 1 |
| Markou, A | 1 |
| Schechter, MD | 1 |
| Cook, PG | 1 |
| Frederickson, RC | 1 |
| Pinsky, C | 1 |
| Aceto, MD | 1 |
| Tucker, SM | 1 |
| Hinson, JR | 1 |
| Ferguson, GS | 1 |
14 other studies available for mecamylamine and Body Weight
| Article | Year |
|---|---|
Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Depressiv | 2015 |
Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice.
Topics: Animals; Body Weight; Brain; Cotinine; Disease Models, Animal; Eating; Electronic Nicotine Delivery | 2015 |
Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Animals; Benzofurans; Body Weight; Carbachol | 2011 |
Limits of learning enhancements with nicotine in old male rats.
Topics: Age Factors; Analysis of Variance; Animals; Body Weight; Discrimination Learning; Dose-Response Rela | 2005 |
Withdrawal from chronic nicotine in adolescent and adult rats.
Topics: Age Factors; Animals; Anxiety; Body Weight; Male; Maze Learning; Mecamylamine; Rats; Rats, Sprague-D | 2006 |
Developmental neurotoxicity of chlorpyrifos: cellular mechanisms.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Chlorpyrifos; DNA; Mecamylamine; Organ Size; Ornithin | 1995 |
Baroreflex resetting but no vascular tolerance in response to transdermal glyceryl trinitrate in conscious rabbits.
Topics: Administration, Cutaneous; Animals; Baroreflex; Blood Pressure; Blood Vessels; Body Weight; Dose-Res | 1996 |
Nicotine abstinence in the mouse.
Topics: Animals; Behavior, Animal; Body Weight; Injections, Subcutaneous; Male; Mecamylamine; Mice; Motor Ac | 1999 |
Neural control of intestinal ion transport and paracellular permeability is altered by nutritional status.
Topics: Animal Nutritional Physiological Phenomena; Animals; Atropine; Bicarbonates; Biological Transport; B | 2000 |
Neonatal nicotine administration influences ethanol-induced behaviors.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Drinking; Ethanol; Male; Mecamylamine; Mic | 2000 |
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression; | 2001 |
Nicotine-induced weight loss in rats without an effect on appetite.
Topics: Animals; Appetite; Body Weight; Depression, Chemical; Feeding Behavior; Female; Hexamethonium Compou | 1976 |
Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat.
Topics: Animals; Atropine; Body Weight; Choline; Humans; Male; Mecamylamine; Morphine Dependence; Parasympat | 1975 |
Chronic nicotine exposure: studies on water intake, body weight, blood pressure and behavior.
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relati | 1987 |