mecamylamine has been researched along with Blood Pressure, High in 86 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both the antinociceptive and toxic effects (convulsions and hypertension) were abolished by pretreatment with the brain penetrant neuronal nAChR antagonist mecamylamine (1 mg/kg s." | 3.70 | Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats. ( Boyce, S; Hill, RG; Rupniak, NMJ; Russell, MGN; Shepheard, SL; Webb, JK, 2000) |
| "Mecamylamine hydrochloride was initially developed for its ganglion-blocking activity and has been marketed as an antihypertensive agent in the United States for >40 years." | 2.41 | Mecamylamine: new therapeutic uses and toxicity/risk profile. ( George, TP; Sanberg, PR; Shytle, RD; Young, JM, 2001) |
| "Obesity is a major risk factor for hypertension." | 1.38 | Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity. ( Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML, 2012) |
| " isoproterenol tachycardia dose-response curves by dose ratios of 5, 18, and 90 in sham rabbits, respectively, and 5, 11, and 23 in wrap rabbits, respectively, indicating significant cardiac beta 1-adrenoceptor antagonism." | 1.28 | Relationship between the sympatholytic action of nebivolol and hypotension. ( Angus, JA; Coles, P; Cox, H; Eisenhofer, G; Ward, JE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (91.86) | 18.7374 |
| 1990's | 3 (3.49) | 18.2507 |
| 2000's | 3 (3.49) | 29.6817 |
| 2010's | 1 (1.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, Y | 1 |
| Shimoji, Y | 1 |
| Fujita, H | 1 |
| Nishino, H | 1 |
| Mizuno, H | 1 |
| Kobayashi, S | 1 |
| Kumakura, S | 1 |
| Belin de Chantemèle, EJ | 1 |
| Ali, MI | 1 |
| Mintz, JD | 1 |
| Rainey, WE | 1 |
| Tremblay, ML | 1 |
| Fulton, DJ | 1 |
| Stepp, DW | 1 |
| MOYER, JH | 2 |
| FORD, R | 1 |
| DENNIS, E | 2 |
| HANDLEY, CA | 1 |
| FREIS, ED | 1 |
| WILSON, IM | 1 |
| COSSIO, P | 2 |
| ELIZALDE, A | 2 |
| WERKO, L | 2 |
| MCQUEEN, EG | 2 |
| SMIRK, FH | 2 |
| MCCORMICK, WF | 1 |
| GRANT, AP | 1 |
| BOYD, JS | 1 |
| VON AHN, B | 1 |
| BIDOGGIA, H | 1 |
| BOVONE, H | 1 |
| REAL, AP | 1 |
| PERRY, HM | 2 |
| SCHROEDER, HA | 2 |
| MOYER, J | 1 |
| HEIDER, C | 1 |
| COTTIER, PT | 1 |
| WELLER, JM | 1 |
| HOOBLER, SW | 1 |
| BERCONSKY, I | 1 |
| NIJENSOHN, CM | 1 |
| LITVAK BRUNO, P | 1 |
| GIORDANO, C | 1 |
| RICCIARDI, S | 1 |
| ORIENTE, P | 1 |
| DENNIS, EW | 1 |
| FORD, RV | 1 |
| HERSHBERGER, RL | 1 |
| KITCHIN, A | 1 |
| LOWTHER, CP | 1 |
| TURNER, RW | 2 |
| ARMAS CRUZ, R | 1 |
| ALVO, M | 1 |
| HARNECKER, J | 1 |
| SUNNAH, E | 1 |
| MELFI, M | 1 |
| MILNE, MD | 1 |
| ROWE, GG | 1 |
| SOMERS, K | 2 |
| MUEHRCKE, RC | 1 |
| CRAWFORD, MA | 1 |
| BARBANO, G | 1 |
| FRIIS, T | 1 |
| CHRISTENSEN, LK | 1 |
| MANZINI, E | 1 |
| MORINI, A | 1 |
| PALTRINIERI, C | 1 |
| DATEY, KK | 1 |
| JOSHI, NK | 1 |
| BIANCHESSI, M | 1 |
| MAUCH, HP | 1 |
| UNGER, AM | 1 |
| PORTER, RR | 1 |
| MARCHETTI, G | 1 |
| NAVA, S | 1 |
| TARTARA, A | 1 |
| LUCCHELLI, P | 1 |
| AGAR, H | 1 |
| BARRETT, CT | 1 |
| EXLEY, KA | 1 |
| BARNETT, AJ | 1 |
| MARSHALL, RJ | 1 |
| BOYD, LJ | 1 |
| HUPPERT, VF | 1 |
| MULINOS, MG | 1 |
| HAMMER, H | 1 |
| SEARS, HT | 1 |
| SNOW, PJ | 1 |
| HOUSTON, IB | 1 |
| VITELLI, A | 1 |
| MOLINARO, R | 1 |
| GRANDIS, C | 1 |
| SIRACUSA, F | 1 |
| MUNSTER, AM | 1 |
| BAUER, GE | 1 |
| EDWARDS, AW | 1 |
| RITCHIE, FL | 1 |
| WHYTE, HM | 1 |
| BOUSVAROS, GA | 1 |
| GALARRAGA, J | 1 |
| COZZOLINO, ER | 1 |
| SMITH, TH | 1 |
| ROSSI, GV | 1 |
| MEDVEDOWSKY, JL | 1 |
| SACCO, JJ | 1 |
| PATEL, BJ | 1 |
| JOSHI, HD | 1 |
| FIFE, R | 1 |
| MORAN, F | 1 |
| PRINEAS, J | 1 |
| GASCARD, E | 1 |
| CASANOVA, P | 1 |
| GIRALDI, A | 2 |
| MAINIERI, L | 1 |
| CHERIE LIGNIERE, E | 1 |
| FOSS, PO | 1 |
| RECORDIER, M | 1 |
| CAMATTE, R | 1 |
| BINE, PL | 1 |
| ROSENBLOOM, SE | 1 |
| SHAPERA, RP | 1 |
| GOLDBLOOM, RS | 1 |
| SHEPS, MC | 1 |
| SHAPIRO, AP | 1 |
| VERCILLO, L | 1 |
| VIDRIO, H | 4 |
| PARDO, EG | 5 |
| SAINANI, GS | 1 |
| NAWAZ, M | 1 |
| HUEGIN, W | 1 |
| SJOERDSMA, A | 1 |
| MATHISEN, HS | 1 |
| VARGAS, R | 2 |
| CHIRONE, E | 1 |
| MILLIGAN, J | 1 |
| URANGAIMAZ, FA | 2 |
| TONNELIER, E | 1 |
| KLAUER, D | 1 |
| CHEKERDEMIAN, M | 1 |
| BECKWITH, JR | 1 |
| CAMP, JL | 1 |
| MOSCA, A | 1 |
| MEIRING, PD | 1 |
| IANNONE, D | 1 |
| FRANCESE, G | 1 |
| MARONDE, RF | 1 |
| BARBOUR, B | 1 |
| FRASHER, W | 1 |
| Bello, CT | 1 |
| Sevy, RW | 1 |
| Harakal, C | 1 |
| Hillyer, PN | 1 |
| Khan, IM | 1 |
| Printz, MP | 1 |
| Yaksh, TL | 1 |
| Taylor, P | 1 |
| Haynes, JM | 1 |
| Hodgson, WC | 1 |
| Cooper, ME | 1 |
| Boyce, S | 1 |
| Webb, JK | 1 |
| Shepheard, SL | 1 |
| Russell, MGN | 1 |
| Hill, RG | 1 |
| Rupniak, NMJ | 1 |
| Young, JM | 1 |
| Shytle, RD | 1 |
| Sanberg, PR | 1 |
| George, TP | 1 |
| Ueno, K | 1 |
| Togashi, H | 1 |
| Matsumoto, M | 1 |
| Ohashi, S | 1 |
| Saito, H | 1 |
| Yoshioka, M | 1 |
| Rick, JH | 1 |
| Oparil, S | 1 |
| Buckingham, RE | 1 |
| Hamilton, TC | 1 |
| Robson, D | 1 |
| Darke, AC | 1 |
| Melnyk, J | 1 |
| Nair, PG | 1 |
| Gaskell, P | 1 |
| Cosnier, D | 2 |
| Duchene-Marullaz, P | 1 |
| Grimal, J | 1 |
| Rispat, G | 2 |
| Streichenberger, G | 2 |
| Labrid, C | 1 |
| Ward, JE | 1 |
| Coles, P | 1 |
| Cox, H | 1 |
| Eisenhofer, G | 1 |
| Angus, JA | 1 |
| Kincaid-Smith, P | 1 |
| Fang, P | 1 |
| Laver, MC | 1 |
| Brod, J | 1 |
| Carstens, E | 1 |
| Griffith, ER | 1 |
| Taylor, N | 1 |
| DeLateur, BJ | 1 |
| Lehmann, JF | 1 |
| López, J | 1 |
| Le Lorie, J | 1 |
| Willard, PW | 1 |
| Beckhelm, GA | 1 |
| Rosenblum, I | 1 |
| Rosenblum, G | 1 |
| Dalla Volta, S | 1 |
| Catanzaro, FJ | 1 |
| Moore-Jones, D | 1 |
| Camel, GH | 1 |
4 reviews available for mecamylamine and Blood Pressure, High
| Article | Year |
|---|---|
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
[MALIGNANT HYPERTENSION].
Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricte | 1964 |
Mecamylamine: new therapeutic uses and toxicity/risk profile.
Topics: Animals; Antihypertensive Agents; Area Under Curve; Autonomic Dysreflexia; Central Nervous System; C | 2001 |
[Pathogenesis of essential hypertension with special reference to therapy].
Topics: Adolescent; Adrenal Glands; Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Diazepam; Diu | 1971 |
1 trial available for mecamylamine and Blood Pressure, High
| Article | Year |
|---|---|
A new look at the treatment of severe hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Clinica | 1973 |
81 other studies available for mecamylamine and Blood Pressure, High
| Article | Year |
|---|---|
Studies on cardiovascular agents. 6. Synthesis and coronary vasodilating and antihypertensive activities of 1,2,4-triazolo[1,5-a]pyrimidines fused to heterocyclic systems.
Topics: Animals; Antihypertensive Agents; Coronary Circulation; Coronary Vessels; Dogs; Female; Guinea Pigs; | 1980 |
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity.
Topics: Adrenergic alpha-1 Receptor Agonists; Albuminuria; Aldosterone; Animals; Blood Pressure; Dose-Respon | 2012 |
Laboratory and clinical observations on mecamylamine as a hypotensive agent.
Topics: Antihypertensive Agents; Camphor; Hypertension; Laboratories; Mecamylamine | 1955 |
Mecamylamine, a new, orally effective, hypotensive agent; experimental and clinical evaluation.
Topics: Antihypertensive Agents; Camphor; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
MECAMYLAMINE hydrochloride.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Treatment of hypertension with pentapirrolidínea and mecamylamine].
Topics: Camphor; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Mecamylamine; a new ganglion-blocking agent for management of hypertension].
Topics: Autonomic Agents; Disease Management; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Use of mecamylamine in the management of hypertension.
Topics: Autonomic Agents; Disease Management; Hypertension; Mecamylamine | 1957 |
Studies on the use of mecamylamine in 10 cases of moderate and severe hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine ileus as a surgical emergency.
Topics: Autonomic Agents; Hypertension; Ileus; Intestinal Obstruction; Mecamylamine | 1957 |
[Mecamylamine therapy of hypertension; preliminary report].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Treatment of arterial hypertension with mecamylamine].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1956 |
[Mecamylamine in hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Neurological manifestations after antihypertensive therapy with mecamylamine.
Topics: Antihypertensive Agents; Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine (inversine) in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Evaluation of mecamylamine in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Treatment of severe arterial hypertension with 2 new ganglionic blocking agents administered orally; ecolid & inversine].
Topics: Autonomic Agents; Chlorisondamine; Ganglionic Blockers; Hypertension; Mecamylamine | 1956 |
[Use of mecamylamine in the treatment of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine in the treatment of hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
Mecamylamine; a ganglion-blocking drug for treating hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine; Monitoring, Physiologic; Professional Practice | 1957 |
[Evaluation of a new hypotensive drug: mecamylamine in malignant hypertension].
Topics: Antihypertensive Agents; Autonomic Agents; Hypertension; Hypertension, Malignant; Hypotension; Mecam | 1957 |
Observations on the pharmacology of mecamylamine.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1957 |
[Clinical observations on a new hypotensive preparation with ganglioplegic action (mecamylamine hydrochloride)].
Topics: Autonomic Agents; Humans; Hypertension; Hypotension; Mecamylamine | 1957 |
[Myocardial infarct caused by mecamylamine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine; Myocardial Infarction | 1957 |
[Use of mecamylamine in the treatment of arterial hypertension].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1957 |
Mecamylamine hydrochloride in the treatment of hypertension.
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1958 |
[Mecamylamine combined with reserpine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine; Reserpine | 1957 |
Mecamylamine-reserpine; results of treatment in severe hypertension.
Topics: Autonomic Agents; Hypertension; Mecamylamine; Reserpine | 1958 |
[Experimental & clinical observation on the activity of a new synthetic ganglioplegic: mecamylamine (3-methylaminoisocamphane hydrochloride)].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine | 1958 |
[Clinical notes on the use of mecamylamine in therapy of arterial hypertension].
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1958 |
Experiences with mecamylamine in hypertensive complications of pregnancy.
Topics: Autonomic Agents; Eclampsia; Female; Humans; Hypertension; Mecamylamine; Pre-Eclampsia; Pregnancy; P | 1958 |
Treatment of hypertension with a combination of chlorothiazide and mecamylamine.
Topics: Acetazolamide; Autonomic Agents; Chlorothiazide; Hypertension; Mecamylamine | 1958 |
Meprobamate in treatment of hypertension; its effects alone and in combination with mecamylamine.
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine; Meprobamate | 1959 |
Treatment of hypertension with pentolinium and mecamylamine.
Topics: Autonomic Agents; Cardiovascular Agents; Hypertension; Mecamylamine; Muscle Relaxants, Central; Pent | 1959 |
Mecamylamine and reserpine in the management of severe and malignant hypertension in Uganda.
Topics: Autonomic Agents; Disease Management; Hypertension; Hypertension, Malignant; Mecamylamine; Reserpine | 1959 |
[Clinical & functional data on the effects of a mecamylamine-reserpine combination in hypertension].
Topics: Autonomic Agents; Humans; Hypertension; Mecamylamine; Reserpine | 1959 |
The side effects of mecamylamine hydrochloride: a review of 50 cases.
Topics: Autonomic Agents; Hypertension; Mecamylamine | 1961 |
Mecamylamine in the treatment of hypertension.
Topics: Antihypertensive Agents; Hypertension; Mecamylamine | 1959 |
Mecamylamine and chlorothiazide in the treatment of hypertension in out-patients.
Topics: Autonomic Agents; Autonomic Nervous System; Chlorothiazide; Hypertension; Mecamylamine; Outpatients | 1961 |
[Treatment of hypertension in pregnancy with mecamylamine and chlorothiazide].
Topics: Autonomic Agents; Autonomic Nervous System; Chlorothiazide; Female; Hypertension; Mecamylamine; Preg | 1961 |
The effect of reserpine and mecamylamine on experimental atheromatosis in the normotensive and hypertensive rat.
Topics: Animals; Arteriosclerosis; Autonomic Agents; Blood Pressure; Cholesterol; Hypertension; Mecamylamine | 1962 |
[Clinical trials of inversine (mecamylamine) in arterial hypertension].
Topics: Hypertension; Mecamylamine | 1963 |
Clinical trial of mecamylamine on patients with hypertension.
Topics: Hypertension; Mecamylamine | 1963 |
Treatment of hypertension in out-patients: mecamylamine, bretylium and guanethidine.
Topics: Bretylium Compounds; Guanethidine; Hypertension; Mecamylamine; Outpatients | 1962 |
[Results of therapeutic use of mecamylamine (Inversine) in the treatment of arterial hypertension].
Topics: Hypertension; Mecamylamine | 1962 |
[The renal hemodynamics of hypertensive subjects treated with mecamylamine associated with reserpine and dihydrochlorothiazide].
Topics: Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Function Tests; Mecamylamine | 1963 |
[Medical treatment of essential hypertension. 4-year case material].
Topics: Chlorothiazide; Essential Hypertension; Humans; Hydralazine; Hypertension; Mecamylamine; Reserpine | 1962 |
[Results of the treatment of arterial hypertension with Mecamylamine].
Topics: Hypertension; Mecamylamine | 1963 |
Technic of controlled drug assay. III. Comparison of guanethidine, mecamylamine and a placebo in the hypertensive patient.
Topics: Guanethidine; Humans; Hypertension; Mecamylamine | 1963 |
[Influence of mecamylamine and of its combination with 1,4-dihydrazinophthalazine or reserpine on renal hemodynamics in patients with arterial hypertension].
Topics: Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Kidney; Mecamylamine; Renal Artery; Res | 1962 |
Development of hypertension during chronic mecamylamine administration in dogs.
Topics: Animals; Dogs; Drug Tolerance; Hypertension; Mecamylamine | 1963 |
TREATMENT OF HYPERTENSION WITH GUANETHIDINE.
Topics: Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Mecamylamine; Toxicology | 1963 |
CHEMOTHERAPY OF HYPERTENSION: YESTERDAY--TODAY--TOMORROW.
Topics: Alkaloids; Amines; Antihypertensive Agents; Chlorisondamine; Chlorothiazide; Dihydroxyphenylalanine; | 1963 |
[DRUG THERAPY OF HIGH BLOOD PRESSURE IN THE PAST, PRESENT AND FUTURE].
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Guanethidine; Humans; Hydralazine; Hyperten | 1963 |
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL MODELS OF ARTERIAL HYPERTENSION].
Topics: Animals; Chlorisondamine; Classification; Cortisone; Dogs; Ganglionic Blockers; Hydrochlorothiazide; | 1964 |
HYPERTENSION AND ITS COMPLICATIONS. 2.
Topics: Amobarbital; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cold Temperature | 1964 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
SUSTAINED HYPERTENSION IN DOGS FOLLOWING CHRONIC ADMINISTRATION OF GANGLIONIC BLOCKING AGENTS.
Topics: Animals; Blood Pressure; Chlorisondamine; Dogs; Ganglionic Blockers; Hydrochlorothiazide; Hypertensi | 1964 |
RECENT TRENDS IN THE MEDICAL TREATMENT OF HYPERTENSION.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Hydralazine; Hypertension; Mecamylamine; Methyldop | 1964 |
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulo | 1965 |
[Treatment of hypertension with reserpine-mecamylamine (cesatin)].
Topics: Hypertension; Mecamylamine; Reserpine | 1959 |
Intravenous mecamylamine (inversine) as a means of determining the effective oral dosage.
Topics: Administration, Intravenous; Humans; Hypertension; Mecamylamine | 1960 |
Relationship between clinical severity of disease and hemodynamic patterns in essential hypertension.
Topics: Adolescent; Adult; Aged; Cardiac Output; Female; Follow-Up Studies; Guanethidine; Hemodynamics; Huma | 1967 |
Further study of the sustained hypertension produced by chronic administration of mecamylamine.
Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Mecamyla | 1967 |
Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension.
Topics: Aconitine; Alkaloids; Animals; Azocines; Blood Pressure; Dihydro-beta-Erythroidine; Dose-Response Re | 1994 |
Rat amylin mediates a pressor response in the anaesthetised rat: implications for the association between hypertension and diabetes mellitus.
Topics: Amino Acid Sequence; Amyloid; Anesthesia, General; Angiotensin I; Animals; Blood Pressure; Calcitoni | 1997 |
Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Behavior, Animal; Body Temperature; Bridged Bicyclo C | 2000 |
Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention Deficit Disorder with Hyperactivity; Beh | 2002 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertensio | 1977 |
Studies on the cardiovascular effects of pindolol in DOCA/saline hypertensive rats.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Blood Pressure; Desoxycorticosterone; Dr | 1977 |
Experimental aldosterone hypertension in the rat.
Topics: Aldosterone; Animals; Blood Pressure; Chlorisondamine; Desoxycorticosterone; Drug Interactions; Etha | 1977 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Dogs; Dose-Response R | 1975 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis.
Topics: Animals; Antihypertensive Agents; Aorta; Autonomic Nervous System; Blood Pressure; Cerebrovascular C | 1975 |
Relationship between the sympatholytic action of nebivolol and hypotension.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Dose-Res | 1992 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Orthostatic hypertension following brain trauma: report of a case.
Topics: Adolescent; Brain Edema; Brain Injuries; Follow-Up Studies; Guanethidine; Hematoma, Subdural; Humans | 1971 |
[Recent progress in the knowledge of arterial hypertension. VII. Acute effects of antihypertensive drugs on kidney function].
Topics: Acute Disease; Animals; Antihypertensive Agents; Dogs; Female; Hemodynamics; Hydralazine; Hypertensi | 1967 |
Differential effect of hypotensive drugs on renal and steroid hypertensive rats.
Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Desoxycorticosterone; Guan | 1968 |
Cardiovascular responses to cyclohexylamine.
Topics: Amines; Animals; Blood Pressure; Bradycardia; Cardiovascular System; Cats; Cocaine; Cyclohexanes; Fe | 1968 |
[Medical therapy of arterial hypertension].
Topics: Antihypertensive Agents; Arteries; Diuretics; Guanethidine; Humans; Hydrazines; Hypertension; Mecamy | 1968 |
Studies on the control of hypertension. 8. Mortality, morbidity, and remissions during twelve years of intensive therapy.
Topics: Chlorisondamine; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hypertension; Mecamylam | 1966 |