Page last updated: 2024-10-30

mecamylamine and Bleeding

mecamylamine has been researched along with Bleeding in 7 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Research Excerpts

ExcerptRelevanceReference
"We examined the response to hemorrhage in conscious normotensive and hypertensive rabbits under control conditions and during efferent blockade of 1) the hormones vasopressin (AVP) and angiotensin II (ANG II), 2) the autonomic nervous system, and 3) autonomic and hormonal inputs."3.69Control of blood pressure and hindlimb conductance during hemorrhage in conscious renal hypertensive rabbits. ( Courneya, CA; Weichert, G, 1995)
"choline was abolished by i."1.35Central choline suppresses plasma renin response to graded haemorrhage in rats. ( Cansev, M; Hamurtekin, E; Ilcol, YO; Isbil-Buyukcoskun, N; Ozluk, K; Ulus, IH, 2008)
"Pre-treatment with mecamylamine (50 mug; i."1.35Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations. ( Cansev, M; Hamurtekin, E; Ilcol, YO; Ulus, IH; Yilmaz, MS, 2008)
" After bleeding so that arterial pressure fell to 40 mmHg, the dose-response relationship for naloxone had two components."1.27Factors influencing the effects of intravenous naloxone on arterial pressure and heart rate after haemorrhage in conscious rabbits. ( Ludbrook, J; Potocnik, SJ; Rutter, PC, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Isbil-Buyukcoskun, N1
Ilcol, YO2
Cansev, M2
Hamurtekin, E2
Ozluk, K1
Ulus, IH2
ADDISON, NV1
TOWERS, JR1
Yilmaz, MS1
Weichert, G1
Courneya, CA1
Rutter, PC1
Potocnik, SJ1
Ludbrook, J1
Selye, H1
Dyball, RE1

Other Studies

7 other studies available for mecamylamine and Bleeding

ArticleYear
Central choline suppresses plasma renin response to graded haemorrhage in rats.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:9

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbachol; Choline; Cholinergic Agonists; Cholines

2008
Subserous jejunal haemorrhages during mecamylamine therapy.
    British medical journal, 1959, May-02, Volume: 1, Issue:5130

    Topics: Autonomic Agents; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intestinal Diseases; Jejunum; Mec

1959
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
    Autonomic & autacoid pharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenal Glands; Animals; Atropine Derivatives; Autonomic Nervous System; Central Nervous System; Cho

2008
Control of blood pressure and hindlimb conductance during hemorrhage in conscious renal hypertensive rabbits.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Analysis of Variance; Angiotensin II; Animals; Arginine Vasopressin; Autonomic Nervous System; Blood

1995
Factors influencing the effects of intravenous naloxone on arterial pressure and heart rate after haemorrhage in conscious rabbits.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:5

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hemorrhage; Meca

1986
Protection by glucocorticoids against ganglioplegics.
    Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Cold Temperature; Drug Antagonism; Fasting; Female; Formaldehy

1970
The effects of drugs on the release of vasopressin.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Calcium Chloride; Chlorpheniramine; Chlorpromazine; Electric Stimulation; Epinephrine; Hemo

1968