mecamylamine has been researched along with Angiogenesis, Pathologic in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of topical or intraocular injection of mecamylamine, a nonspecific nAChR antagonist, or targeted deletion of α7- or α9-nAChRs on ischemia-induced retinal NV was determined by comparing the amount of retinal NV at P17 in these mice versus appropriate controls." | 3.85 | The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity. ( Abraham, S; Campochiaro, PA; Chadha, R; Cooke, JP; Fortmann, SD; Hackett, SF; Seidel, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hackett, SF | 1 |
| Seidel, C | 1 |
| Abraham, S | 1 |
| Chadha, R | 1 |
| Fortmann, SD | 1 |
| Campochiaro, PA | 1 |
| Cooke, JP | 3 |
| Heeschen, C | 2 |
| Weis, M | 1 |
| Aicher, A | 1 |
| Dimmeler, S | 1 |
| Zhu, BQ | 1 |
| Sievers, RE | 1 |
| Karliner, JS | 1 |
| Parmley, WW | 1 |
| Glantz, SA | 1 |
| Li, XW | 1 |
| Wang, H | 1 |
4 other studies available for mecamylamine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity.
Topics: Animals; Animals, Newborn; Cholinergic Agents; Disease Models, Animal; Ischemia; Mecamylamine; Mice; | 2017 |
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Carcinoma, Lewis Lung; Cell Division; Cells, Cultu | 2002 |
Second hand smoke stimulates tumor angiogenesis and growth.
Topics: Animals; Carcinoma, Lewis Lung; Chemokine CCL2; Endothelial Cells; Hydroxymethylglutaryl CoA Reducta | 2003 |
Non-neuronal nicotinic alpha 7 receptor, a new endothelial target for revascularization.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Calcium; Cell Proliferation; Cells, | 2006 |