Page last updated: 2024-10-30

mecamylamine and Amphetamine Abuse

mecamylamine has been researched along with Amphetamine Abuse in 2 studies

Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Research Excerpts

ExcerptRelevanceReference
"The symptom of "diminished interest or pleasure" in rewarding stimuli is an affective symptom of nicotine and amphetamine withdrawal, and a core symptom of depression."3.71Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. ( Harrison, AA; Liem, YT; Markou, A, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrison, AA1
Liem, YT1
Markou, A1
Schoffelmeer, AN1
De Vries, TJ1
Wardeh, G1
van de Ven, HW1
Vanderschuren, LJ1

Other Studies

2 other studies available for mecamylamine and Amphetamine Abuse

ArticleYear
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1

    Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression;

2001
Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-15, Volume: 22, Issue:8

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Association Learning; Behavior, Animal; Central

2002