mecamylamine has been researched along with Amnesia-Memory Loss in 12 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to investigate possible involvement of the central amygdala (CeA) nicotinic acetylcholine (nACh) and 5-hydroxytryptamine 1A (5-HT1A) receptors in the reversal effect of nicotine and 3,4-methylenedioxy-N-methylamphetamine (MDMA or ecstasy) on morphine-induced amnesia." | 7.80 | Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia. ( Rezayof, A; Tirgar, F; Zarrindast, MR, 2014) |
| "The effects of nicotine on carbon monoxide (CO)-induced amnesia in mice were investigated using a step-down type passive avoidance task." | 7.69 | Nootropic effect of nicotine on carbon monoxide (CO)-induced delayed amnesia in mice. ( Hiramatsu, M; Kameyama, T; Nabeshima, T; Satoh, H, 1994) |
| "The present study was designed to investigate possible involvement of the central amygdala (CeA) nicotinic acetylcholine (nACh) and 5-hydroxytryptamine 1A (5-HT1A) receptors in the reversal effect of nicotine and 3,4-methylenedioxy-N-methylamphetamine (MDMA or ecstasy) on morphine-induced amnesia." | 3.80 | Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia. ( Rezayof, A; Tirgar, F; Zarrindast, MR, 2014) |
| "The present study evaluated the possible role of nicotinic acetylcholine receptors of the dorsal hippocampus on morphine-induced amnesia and morphine state-dependent memory in adult male Wistar rats." | 3.74 | Involvement of dorsal hippocampal nicotinic receptors in the effect of morphine on memory retrieval in passive avoidance task. ( Khajehpour, L; Rezayof, A; Zarrindast, MR, 2008) |
| "The effects of nicotine on carbon monoxide (CO)-induced amnesia in mice were investigated using a step-down type passive avoidance task." | 3.69 | Nootropic effect of nicotine on carbon monoxide (CO)-induced delayed amnesia in mice. ( Hiramatsu, M; Kameyama, T; Nabeshima, T; Satoh, H, 1994) |
| "Cholestasis was induced by the ligation of the common bile duct." | 1.38 | Possible interaction between opioidergic and cholinergic systems of CA1 in cholestasis-induced amnesia in mice. ( Hoseindoost, S; Nasehi, M; Zarrindast, MR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tirgar, F | 1 |
| Rezayof, A | 3 |
| Zarrindast, MR | 5 |
| Nasehi, M | 2 |
| Sharifi, S | 1 |
| Hoseindoost, S | 1 |
| Hsieh, MT | 1 |
| Kuo, LH | 1 |
| Tsai, FH | 1 |
| Wang, WH | 1 |
| Wu, CR | 1 |
| Sapronov, NS | 1 |
| Fedotova, YO | 1 |
| Kuznetsova, NN | 1 |
| Khajehpour, L | 1 |
| Darbandi, N | 1 |
| Hiramatsu, M | 2 |
| Satoh, H | 1 |
| Kameyama, T | 2 |
| Nabeshima, T | 2 |
| Sasaki, M | 1 |
| Manetti, D | 1 |
| Ghelardini, C | 1 |
| Bartolini, A | 1 |
| Bellucci, C | 1 |
| Dei, S | 1 |
| Galeotti, N | 1 |
| Gualtieri, F | 1 |
| Romanelli, MN | 1 |
| Scapecchi, S | 1 |
| Teodori, E | 1 |
| Mohamed, AF | 1 |
| Matsumoto, K | 1 |
| Tabata, K | 1 |
| Takayama, H | 1 |
| Kitajima, M | 1 |
| Watanabe, H | 1 |
| Elrod, K | 1 |
| Buccafusco, JJ | 1 |
12 other studies available for mecamylamine and Amnesia-Memory Loss
| Article | Year |
|---|---|
Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia.
Topics: Amnesia; Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Male; Mecamylamine; | 2014 |
Involvement of the cholinergic system of CA1 on harmane-induced amnesia in the step-down passive avoidance test.
Topics: Amnesia; Animals; Anxiety; Avoidance Learning; CA1 Region, Hippocampal; Cholinergic Fibers; Dose-Res | 2012 |
Possible interaction between opioidergic and cholinergic systems of CA1 in cholestasis-induced amnesia in mice.
Topics: Amnesia; Animals; Animals, Outbred Strains; CA1 Region, Hippocampal; Cholestasis; Disease Models, An | 2012 |
Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relations | 2002 |
Antiamnestic effect of alpha7-nicotinic receptor agonist RJR-2403 in middle-aged ovariectomized rats with Alzheimer type dementia.
Topics: Acetylcholine; Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Drug Therapy, Combination; E | 2006 |
Involvement of dorsal hippocampal nicotinic receptors in the effect of morphine on memory retrieval in passive avoidance task.
Topics: Amnesia; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response R | 2008 |
Nicotinic acetylcholine receptors of the ventral tegmental area are involved in mediating morphine-state-dependent learning.
Topics: Amnesia; Analgesics, Opioid; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Drug Int | 2008 |
Nootropic effect of nicotine on carbon monoxide (CO)-induced delayed amnesia in mice.
Topics: Amnesia; Animals; Avoidance Learning; Carbon Monoxide Poisoning; Electroshock; Male; Mecamylamine; M | 1994 |
Effects of dynorphin A (1-13) on carbon monoxide-induced delayed amnesia in mice.
Topics: Amnesia; Animals; Carbon Monoxide Poisoning; Dizocilpine Maleate; Dynorphins; Excitatory Amino Acid | 1997 |
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Topics: Adrenergic alpha-Agonists; Amnesia; Animals; Avoidance Learning; Baclofen; Clonidine; Dose-Response | 2000 |
Effects of Uncaria tomentosa total alkaloid and its components on experimental amnesia in mice: elucidation using the passive avoidance test.
Topics: Alkaloids; Amnesia; Animals; Avoidance Learning; Cat's Claw; Diazepam; Dose-Response Relationship, D | 2000 |
Correlation of the amnestic effects of nicotinic antagonists with inhibition of regional brain acetylcholine synthesis in rats.
Topics: Acetylcholine; Amnesia; Animals; Avoidance Learning; Blood Pressure; Brain; Dose-Response Relationsh | 1991 |