mecamylamine has been researched along with Alloxan Diabetes in 4 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study assessed the sex-dependent effects of insulin resistance on the reinforcing effects of nicotine." | 8.02 | The emergence of insulin resistance following a chronic high-fat diet regimen coincides with an increase in the reinforcing effects of nicotine in a sex-dependent manner. ( Cruz, B; Galindo, KI; Giner, P; Matos-Ocasio, F; Nazarian, A; O'Dell, LE; Ortegon, S; Rodriguez-Crespo, A; Serafine, KM; Uribe, KP, 2021) |
| "The present study assessed the sex-dependent effects of insulin resistance on the reinforcing effects of nicotine." | 4.02 | The emergence of insulin resistance following a chronic high-fat diet regimen coincides with an increase in the reinforcing effects of nicotine in a sex-dependent manner. ( Cruz, B; Galindo, KI; Giner, P; Matos-Ocasio, F; Nazarian, A; O'Dell, LE; Ortegon, S; Rodriguez-Crespo, A; Serafine, KM; Uribe, KP, 2021) |
| " Using the multiple low-dose streptozotocin (MLD-STZ) model of experimental autoimmune diabetes, we previously reported that pretreatment with a specific acetylcholinesterase inhibitor (AChEI), paraoxon, prevented the development of hyperglycemia in C57BL/6 mice." | 3.91 | Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes. ( Al-Mansori, A; Al-Ramadi, BK; Bashir, G; Fernández-Cabezudo, MJ; George, JA; Lorke, DE; Mohamed, YA; Petroianu, G; Qureshi, MM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cruz, B | 2 |
| Ortegon, S | 1 |
| Giner, P | 1 |
| Matos-Ocasio, F | 1 |
| Rodriguez-Crespo, A | 1 |
| Uribe, KP | 1 |
| Galindo, KI | 1 |
| Serafine, KM | 1 |
| Nazarian, A | 2 |
| O'Dell, LE | 2 |
| Pipkin, JA | 1 |
| Flores, RJ | 1 |
| Hinojosa, CA | 1 |
| Carcoba, LM | 1 |
| Ibarra, M | 1 |
| Francis, W | 1 |
| Fernández-Cabezudo, MJ | 1 |
| George, JA | 1 |
| Bashir, G | 1 |
| Mohamed, YA | 1 |
| Al-Mansori, A | 1 |
| Qureshi, MM | 1 |
| Lorke, DE | 1 |
| Petroianu, G | 1 |
| Al-Ramadi, BK | 1 |
| Minker, E | 1 |
| Kac, P | 1 |
| Blazsó, G | 1 |
| Koltai, M | 1 |
4 other studies available for mecamylamine and Alloxan Diabetes
| Article | Year |
|---|---|
The emergence of insulin resistance following a chronic high-fat diet regimen coincides with an increase in the reinforcing effects of nicotine in a sex-dependent manner.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Dose-Response Relationship, | 2021 |
Both nicotine reward and withdrawal are enhanced in a rodent model of diabetes.
Topics: Animals; Conditioning, Psychological; Diabetes Mellitus, Experimental; Dose-Response Relationship, D | 2017 |
Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes.
Topics: Acetylcholinesterase; Animals; Atropine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; | 2019 |
A study of the origin of altered pharmacological reactivity of synaptic structures caused by diabetes and pretreatment with contrainsular agents.
Topics: Animals; Cortisone; Diabetes Mellitus, Experimental; Female; Ganglia, Sympathetic; Hexamethonium; He | 1984 |