mecamylamine has been researched along with Ache in 52 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present investigation, we used intrathecal administration of drugs to rats to show that muscarinic or nicotinic agonists such as bethanechol (BCh) and dimethylphenylpiperazinium (DM), respectively, dose-dependently increased the tail flick latency and reduced the pain produced by a surgical incision performed on the plantar aspect of a hind paw." | 7.72 | Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats. ( Prado, WA; Segalla, DK, 2004) |
| "To assess the possible role of nicotinergic control in nociception and pain, experiments were carried out on rats under urethane anesthesia in which nociceptive activity was elicited by electrical stimulation of afferent C fibers in the sural nerve and recorded from single neurones in the thalamus and from ascending axons in the spinal cord." | 7.68 | Depression by nicotine of pain-related nociceptive activity in the rat thalamus and spinal cord. ( Baldauf, J; Jurna, I; Krauss, P, 1993) |
| ") 1 h prior to testing, produced dose-dependent inhibition of acetic acid-induced visceral pain, with ID50 value of 241." | 3.75 | Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. ( Calixto, JB; Chaves, J; Ferreira, VM; Guginski, G; Luiz, AP; Martins, DF; Massaro, M; Mattos, RW; Santos, AR; Silva, MD; Silveira, D, 2009) |
| "Antinociceptive activity of coniine was tested dose in Hotplate test (thermal pain model) and in Writhing test (chemical pain model) in different nociception models." | 3.75 | Antinociceptive activity of coniine in mice. ( Arihan, O; Boz, M; Ilhan, M; Iskit, AB, 2009) |
| "5, 1, or 2 mg/kg) induced analgesia, with pain scores significantly lower than those seen after saline, lower doses of Sazetidine-A, and epibatidine (P < 0." | 3.74 | Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug. ( Cucchiaro, G; Gonzalez-Sulser, A; Kellar, KJ; Xiao, Y, 2008) |
| " In the present investigation, we used intrathecal administration of drugs to rats to show that muscarinic or nicotinic agonists such as bethanechol (BCh) and dimethylphenylpiperazinium (DM), respectively, dose-dependently increased the tail flick latency and reduced the pain produced by a surgical incision performed on the plantar aspect of a hind paw." | 3.72 | Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats. ( Prado, WA; Segalla, DK, 2004) |
| "Physostigmine has different effects on allodynia and nociception, which suggests that different cholinergic (muscarinic) mechanisms may be involved in neuropathic and nociceptive pain." | 3.70 | Systemic physostigmine shows antiallodynic effects in neuropathic rats. ( Kalso, E; Kontinen, VK; Paananen, S; Pöyhiä, R; Xu, M, 1999) |
| "Nicotine evokes pain in the skin and oral mucosa and excites a subpopulation of cutaneous nociceptors, but little is known about the central transmission of chemogenic pain." | 3.70 | Activation of spinal wide dynamic range neurons by intracutaneous microinjection of nicotine. ( Carstens, E; Jinks, SL, 1999) |
| "To characterize the role of neuronal nicotinic acetylcholine receptors (nAChRs) in oral irritation and pain, we employed the method of c-fos immunohistochemistry to map the locations and numbers of brainstem neurons that express the immediate-early gene, c-fos, after application of nicotine to the tongue, either alone or after pretreatment with cholinergic antagonists." | 3.70 | Role of neuronal nicotinic-acetylcholine receptors in the activation of neurons in trigeminal subnucleus caudalis by nicotine delivered to the oral mucosa. ( Carstens, E; Carstens, MI; Dessirier, JM; Jinks, SL; Simons, CT, 2000) |
| "To assess the possible role of nicotinergic control in nociception and pain, experiments were carried out on rats under urethane anesthesia in which nociceptive activity was elicited by electrical stimulation of afferent C fibers in the sural nerve and recorded from single neurones in the thalamus and from ascending axons in the spinal cord." | 3.68 | Depression by nicotine of pain-related nociceptive activity in the rat thalamus and spinal cord. ( Baldauf, J; Jurna, I; Krauss, P, 1993) |
| "Pretreatment with atropine at 5 mg/kg, but not at 2." | 1.37 | Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin. ( Feng, YL; Lin, HM; Liu, YL; Qin, ZH; Reid, PF; Shi, GN; Yang, SL, 2011) |
| " This hypothesis was further established with methyllycaconitine completely inhibited the agonist effect when dosed intrathecally (1% +/- 7%)." | 1.35 | Activation of the alpha7-nicotinic acetylcholine receptor reverses complete freund adjuvant-induced mechanical hyperalgesia in the rat via a central site of action. ( Billinton, A; Bingham, S; Chessell, IP; Clayton, NM; Hatcher, JP; Hille, CJ; Medhurst, SJ, 2008) |
| " In the abdominal constriction test, LXM-10 had a significant dose-response effect, and the maximal inhibition ratio was 79." | 1.34 | Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice. ( Li, CL; Li, RT; Sun, Q; Ye, J; Yue, CQ, 2007) |
| "Pretreatment with chlorisondamine (0." | 1.33 | ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model. ( Decker, MW; Honore, P; Lynch, JJ; Mikusa, JP; Wade, CL, 2005) |
| " This study examines the hypothesis for the first time that the neonicotinoid insecticides and their imine metabolites and analogs display analgesic (antinociceptive) activity or adverse toxic effects associated with their action on binding to the alpha 4 beta 2 nicotinic acetylcholine receptor (AChR) subtype." | 1.31 | Analgesic and toxic effects of neonicotinoid insecticides in mice. ( Casida, JE; Cowan, A; Tomizawa, M, 2001) |
| "Development of analgesic agents for the treatment of severe pain requires the identification of compounds that are devoid of opioid receptor liabilities." | 1.30 | Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. ( Arneric, SP; Bannon, AW; Bitner, RS; Curzon, P; Decker, MW; Diaz, A; Dickenson, AH; Donnelly-Roberts, D; Holladay, MW; Porsolt, RD; Puttfarcken, PS; Williams, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (11.54) | 18.7374 |
| 1990's | 12 (23.08) | 18.2507 |
| 2000's | 24 (46.15) | 29.6817 |
| 2010's | 9 (17.31) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Tobaldini, G | 1 |
| Andersen, EOL | 1 |
| Polato, JJ | 1 |
| Guilhen, VA | 1 |
| Gaspar, JC | 1 |
| Lazzarim, MK | 1 |
| Sardi, NF | 1 |
| Fischer, L | 1 |
| Li, W | 1 |
| Cai, J | 1 |
| Wang, BH | 1 |
| Huang, L | 1 |
| Fan, J | 1 |
| Wang, Y | 1 |
| Hirotsu, C | 1 |
| Pedroni, MN | 1 |
| Berro, LF | 1 |
| Tufik, S | 1 |
| Andersen, ML | 1 |
| Papke, RL | 1 |
| Stokes, C | 1 |
| Muldoon, P | 1 |
| Imad Damaj, M | 1 |
| Giorno, TBS | 1 |
| Silva, BVD | 1 |
| Pinto, ADC | 1 |
| Fernandes, PD | 2 |
| Cucchiaro, G | 1 |
| Xiao, Y | 1 |
| Gonzalez-Sulser, A | 1 |
| Kellar, KJ | 1 |
| Guginski, G | 1 |
| Luiz, AP | 1 |
| Silva, MD | 1 |
| Massaro, M | 1 |
| Martins, DF | 1 |
| Chaves, J | 1 |
| Mattos, RW | 1 |
| Silveira, D | 1 |
| Ferreira, VM | 1 |
| Calixto, JB | 1 |
| Santos, AR | 1 |
| Arihan, O | 1 |
| Boz, M | 1 |
| Iskit, AB | 1 |
| Ilhan, M | 1 |
| Gear, RW | 1 |
| Levine, JD | 1 |
| Munro, G | 1 |
| Dyhr, H | 1 |
| Grunnet, M | 1 |
| Shi, GN | 1 |
| Liu, YL | 1 |
| Lin, HM | 1 |
| Yang, SL | 1 |
| Feng, YL | 1 |
| Reid, PF | 1 |
| Qin, ZH | 1 |
| Motta, PG | 1 |
| Perez, AC | 1 |
| Alves, DP | 1 |
| Duarte, ID | 1 |
| Petronilho, A | 1 |
| Reis, GM | 1 |
| Dias, QM | 1 |
| Fais, RS | 1 |
| Prado, WA | 3 |
| Pinheiro, MM | 1 |
| Boylan, F | 1 |
| Dussor, GO | 1 |
| Helesic, G | 1 |
| Hargreaves, KM | 1 |
| Flores, CM | 1 |
| Caban, AJ | 1 |
| Hama, AT | 2 |
| Lee, JW | 1 |
| Sagen, J | 2 |
| Segalla, DK | 1 |
| Dubé, GR | 1 |
| Kohlhaas, KL | 1 |
| Rueter, LE | 2 |
| Surowy, CS | 1 |
| Meyer, MD | 2 |
| Briggs, CA | 1 |
| Lynch, JJ | 1 |
| Wade, CL | 1 |
| Mikusa, JP | 2 |
| Decker, MW | 4 |
| Honore, P | 2 |
| Simons, CT | 2 |
| Cuellar, JM | 1 |
| Moore, JA | 1 |
| Pinkerton, KE | 1 |
| Uyeminami, D | 1 |
| Carstens, MI | 2 |
| Carstens, E | 4 |
| Damaj, MI | 2 |
| Fonck, C | 1 |
| Marks, MJ | 1 |
| Deshpande, P | 1 |
| Labarca, C | 1 |
| Lester, HA | 1 |
| Collins, AC | 1 |
| Martin, BR | 2 |
| Yue, CQ | 1 |
| Ye, J | 1 |
| Li, CL | 1 |
| Li, RT | 1 |
| Sun, Q | 1 |
| Jafari, MR | 1 |
| Golmohammadi, S | 1 |
| Ghiasvand, F | 1 |
| Zarrindast, MR | 1 |
| Djahanguiri, B | 1 |
| Kiguchi, N | 1 |
| Maeda, T | 1 |
| Tsuruga, M | 1 |
| Yamamoto, A | 1 |
| Yamamoto, C | 1 |
| Ozaki, M | 1 |
| Kishioka, S | 1 |
| Joshi, SK | 1 |
| Weaver, B | 1 |
| Medhurst, SJ | 1 |
| Hatcher, JP | 1 |
| Hille, CJ | 1 |
| Bingham, S | 1 |
| Clayton, NM | 1 |
| Billinton, A | 1 |
| Chessell, IP | 1 |
| Watkins, LR | 1 |
| Katayama, Y | 1 |
| Kinscheck, IB | 1 |
| Mayer, DJ | 1 |
| Hayes, RL | 1 |
| Jurna, I | 1 |
| Krauss, P | 1 |
| Baldauf, J | 1 |
| Franco, AC | 1 |
| Bannon, AW | 2 |
| Holladay, MW | 2 |
| Curzon, P | 1 |
| Donnelly-Roberts, D | 1 |
| Puttfarcken, PS | 1 |
| Bitner, RS | 1 |
| Diaz, A | 1 |
| Dickenson, AH | 1 |
| Porsolt, RD | 1 |
| Williams, M | 2 |
| Arneric, SP | 2 |
| Buckley, MJ | 1 |
| Kim, DJ | 1 |
| Ryther, KB | 1 |
| Lin, NH | 1 |
| Wasicak, JT | 1 |
| Khan, IM | 1 |
| Buerkle, H | 1 |
| Taylor, P | 1 |
| Yaksh, TL | 1 |
| Lawand, NB | 1 |
| Lu, Y | 1 |
| Westlund, KN | 1 |
| Pöyhiä, R | 1 |
| Xu, M | 1 |
| Kontinen, VK | 1 |
| Paananen, S | 1 |
| Kalso, E | 1 |
| Jinks, SL | 2 |
| Hentall, ID | 1 |
| Dessirier, JM | 1 |
| Meyer, EM | 1 |
| Hama, A | 1 |
| Menzaghi, F | 2 |
| Lloyd, GK | 1 |
| Tomizawa, M | 1 |
| Cowan, A | 1 |
| Casida, JE | 1 |
| Eger, EI | 1 |
| Zhang, Y | 1 |
| Laster, M | 1 |
| Flood, P | 1 |
| Kendig, JJ | 1 |
| Sonner, JM | 1 |
| Rodgers, RJ | 1 |
| Zhuo, M | 1 |
| Gebhart, GF | 1 |
| Cooley, JE | 1 |
| Villarosa, GA | 1 |
| Lombardo, TW | 1 |
| Moss, RA | 1 |
| Fowler, SC | 1 |
| Sult, S | 1 |
| Christensen, MK | 1 |
| Smith, DF | 1 |
| Sansone, M | 1 |
| Castellano, C | 1 |
| Battaglia, M | 1 |
| Ammassari-Teule, M | 1 |
| Blinowska, KJ | 1 |
| Kowalczyk, M | 1 |
| Franaszczuk, PJ | 1 |
| Mitraszewski, P | 1 |
| Yamada, S | 1 |
| Kagawa, Y | 1 |
| Takayanagi, N | 1 |
| Hayashi, E | 1 |
| Tsuji, K | 1 |
| Kosuge, T | 1 |
| Phan, DV | 1 |
| Dóda, M | 1 |
| Bite, A | 1 |
| György, L | 1 |
52 other studies available for mecamylamine and Ache
| Article | Year |
|---|---|
Pain and stress: functional evidence that supra-spinal mechanisms involved in pain-induced analgesia mediate stress-induced analgesia.
Topics: Analgesia; Animals; Capsaicin; Cholinergic Neurons; Hyperalgesia; Male; Mecamylamine; Nicotine; Noci | 2020 |
Antinociceptive effects of novel epibatidine analogs through activation of α4β2 nicotinic receptors.
Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Co | 2018 |
Nicotine and sleep deprivation: impact on pain sensitivity and immune modulation in rats.
Topics: Animals; Hyperalgesia; Immunity; Interleukin-4; Interleukin-6; Male; Mecamylamine; Nicotine; Pain; P | 2018 |
Similar activity of mecamylamine stereoisomers in vitro and in vivo.
Topics: Analgesics; Animals; Hot Temperature; Humans; Male; Mecamylamine; Mice; Mice, Inbred ICR; Nicotinic | 2013 |
Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice.
Topics: Analgesics; Animals; Atropine; Dose-Response Relationship, Drug; Isatin; Mecamylamine; Mice; Morphin | 2016 |
Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug.
Topics: Analgesics; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Diseas | 2008 |
Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Atropine; Cinnamates; Depsides; Dose-Response Relationsh | 2009 |
Antinociceptive activity of coniine in mice.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Conium; Drug Synergism; Male; Mecamylamine; Mice; Morph | 2009 |
Rostral ventral medulla cholinergic mechanism in pain-induced analgesia.
Topics: Analgesia; Animals; Electromyography; Male; Mecamylamine; Medulla Oblongata; Microinjections; Neural | 2009 |
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-R | 2010 |
Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin.
Topics: Aconitine; Adjuvants, Anesthesia; Analgesics; Animals; Antihypertensive Agents; Atropine; Cobra Neur | 2011 |
Modulation of peripheral inflammatory pain thresholds by M(1) and nicotinic receptor antagonists.
Topics: Acetylcholine; Animals; Carrageenan; Dinoprostone; Hyperalgesia; Inflammation; Male; Mecamylamine; N | 2011 |
Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microin | 2012 |
Antinociceptive effect of the Orbignya speciosa Mart. (Babassu) leaves: evidence for the involvement of apigenin.
Topics: Analgesics; Animals; Apigenin; Arecaceae; Aspirin; Atropine; Brazil; Disease Models, Animal; Dose-Re | 2012 |
Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron.
Topics: Acetylcholine; Analysis of Variance; Animals; Arecoline; Atropine; Behavior, Animal; Bungarotoxins; | 2004 |
Enhanced antinociception by nicotinic receptor agonist epibatidine and adrenal medullary transplants in the spinal subarachnoid space.
Topics: Adrenal Medulla; Analgesics; Animals; Bridged Bicyclo Compounds, Heterocyclic; Male; Mecamylamine; N | 2004 |
Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats.
Topics: Acetylcholine; Analgesics; Analysis of Variance; Animals; Atropine; Bethanechol; Cholinergic Agonist | 2004 |
Loss of functional neuronal nicotinic receptors in dorsal root ganglion neurons in a rat model of neuropathic pain.
Topics: Acetylcholine; Animals; Azetidines; Cell Count; Cells, Cultured; Disease Models, Animal; Dose-Respon | 2005 |
ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model.
Topics: Acetylcholine; Analgesia; Animals; Azetidines; Chlorisondamine; Disease Models, Animal; Dose-Respons | 2005 |
Nicotinic receptor involvement in antinociception induced by exposure to cigarette smoke.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mecamylamine; Naltrexon | 2005 |
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice.
Topics: Alkaloids; Analgesics; Animals; Azocines; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyc | 2007 |
Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice.
Topics: Analgesics; Animals; Atropine; Atropine Derivatives; Body Temperature; Drug Evaluation, Preclinical; | 2007 |
Influence of nicotinic receptor modulators on CB2 cannabinoid receptor agonist (JWH133)-induced antinociception in mice.
Topics: Animals; Cannabinoids; Dose-Response Relationship, Drug; Formaldehyde; Male; Mecamylamine; Mice; Mot | 2007 |
Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Down-Regulation; Dynorphins; Enkephalin, Meth | 2008 |
Morphine and ABT-594 (a nicotinic acetylcholine agonist) exert centrally mediated antinociception in the rat cyclophosphamide cystitis model of visceral pain.
Topics: Analgesics; Animals; Azetidines; Behavior, Animal; Brain; Chlorisondamine; Cyclophosphamide; Cystiti | 2008 |
Activation of the alpha7-nicotinic acetylcholine receptor reverses complete freund adjuvant-induced mechanical hyperalgesia in the rat via a central site of action.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzofurans; Dose-Res | 2008 |
Muscarinic cholinergic mediation of opiate and non-opiate environmentally induced analgesias.
Topics: Analgesia; Animals; Central Nervous System; Cholinergic Fibers; Conditioning, Classical; Electroshoc | 1984 |
Depression by nicotine of pain-related nociceptive activity in the rat thalamus and spinal cord.
Topics: Afferent Pathways; Analgesics; Animals; Atropine; Blood Pressure; Electric Stimulation; Female; Inje | 1993 |
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists | 1996 |
Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; D | 1998 |
Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Hexamethonium; Lethal Dose 50; Male; Maze Learning; M | 1998 |
Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists.
Topics: Alkaloids; Analgesia; Animals; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Escape Reaction; H | 1998 |
Nicotinic cholinergic receptors: potential targets for inflammatory pain relief.
Topics: Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Behavior, Animal; Bridged Bicyclo Compou | 1999 |
Systemic physostigmine shows antiallodynic effects in neuropathic rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Atropine; Cholinergic Antagonists; Dose-Response Relationsh | 1999 |
Activation of spinal wide dynamic range neurons by intracutaneous microinjection of nicotine.
Topics: Action Potentials; Animals; Azetidines; Histamine; Histamine H1 Antagonists; Hot Temperature; Male; | 1999 |
Spinal CSF from rats with painful peripheral neuropathy evokes catecholamine release from chromaffin cells in vitro.
Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Cerebrospinal Fluid; Cerebrospina | 2000 |
Role of neuronal nicotinic-acetylcholine receptors in the activation of neurons in trigeminal subnucleus caudalis by nicotine delivered to the oral mucosa.
Topics: Administration, Oral; Animals; Atropine; Male; Mecamylamine; Mouth Mucosa; Muscarinic Antagonists; N | 2000 |
Spinal mechanisms underlying A-85380-induced effects on acute thermal pain.
Topics: Adrenergic alpha-Agonists; Animals; Azetidines; Behavior, Animal; Bridged Bicyclo Compounds, Heteroc | 2000 |
The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Benzylidene Compounds; Bungarotoxins; | 2000 |
Antagonist of nicotinic acetylcholine receptors (nAChR) enhances formalin-induced nociception in rats: tonic role of nAChRs in the control of pain following injury.
Topics: Acute Disease; Animals; Chronic Disease; Male; Mecamylamine; Nicotinic Antagonists; Nociceptors; Pai | 2001 |
The antinociceptive effect of intrathecal administration of epibatidine with clonidine or neostigmine in the formalin test in rats.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocy | 2001 |
Analgesic and toxic effects of neonicotinoid insecticides in mice.
Topics: Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dose-Re | 2001 |
Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Atropine; Cholinergic Antagonists; Injections, Intraperitoneal; In | 2002 |
Effects of nicotine, mecamylamine, and hexamethonium on shock-induced fighting, pain reactivity, and locomotor behaviour in rats.
Topics: Aggression; Animals; Electroshock; Hexamethonium Compounds; Humans; Male; Mecamylamine; Motor Activi | 1979 |
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat.
Topics: Amidines; Analysis of Variance; Animals; Atropine; Blood Pressure; Brain; Electric Stimulation; Hear | 1991 |
Effect of pCPA on nicotine-induced analgesia.
Topics: Analgesia; Animals; Drug Interactions; Fenclonine; Male; Mecamylamine; Naloxone; Nicotine; Pain; Rat | 1990 |
Antinociceptive effects of the stereoisomers of nicotine given intrathecally in spinal rats.
Topics: Analgesia; Animals; Injections, Spinal; Male; Mecamylamine; Nicotine; Pain; Pain Measurement; Rats; | 1990 |
Oxiracetam prevents mecamylamine-induced impairment of active, but not passive, avoidance learning in mice.
Topics: Animals; Avoidance Learning; Drug Interactions; Electric Stimulation; Male; Mecamylamine; Mice; Mice | 1990 |
The EEG time series parametrization method in the study of nociception.
Topics: Algorithms; Animals; Atropine; Brain; Cholinergic Fibers; Electroencephalography; Male; Mecamylamine | 1989 |
Inhibition by neosurugatoxin of nicotine-induced antinociception.
Topics: Animals; Central Nervous System; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mice; M | 1986 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Antin ociceptive activity of nicotine.
Topics: Acetates; Analgesia; Animals; Dimethylphenylpiperazinium Iodide; Drug Tolerance; Injections, Intrape | 1973 |