mebeverine has been researched along with Colonic Diseases, Functional in 15 studies
mebeverine: RN given refers to parent cpd; structure
Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Very few adverse events were noted and a causal relationship with the study medications was judged as improbable or definitely unrelated." | 2.68 | A double-blind crossover comparison study of the safety and efficacy of mebeverine with mebeverine sustained release in the treatment of irritable bowel syndrome. ( Ceuppens, M; Hendrickx, B; Mayeur, S; Meeus, MA; Rosillon, D; Van Outryve, M, 1995) |
| " INTERVENTION Dosage was 135 mg of mebeverine hydrochloride, three times daily before meals, together with advice on high-fibre dietary intake, or 135 mg of mebeverine hydrochloride plus 3." | 2.67 | A comparison of mebeverine with high-fibre dietary advice and mebeverine plus ispaghula in the treatment of irritable bowel syndrome: an open, prospectively randomised, parallel group study. ( Atkinson, SN; Chapman, ND; Grillage, MG; Mazumder, R, 1990) |
| "Mebeverine was significantly more effective when combined with Motival (18 out of 24 improved) than with lorazepam (10 improved)." | 2.65 | Comparison of various treatments for irritable bowel syndrome. ( Ritchie, JA; Truelove, SC, 1980) |
| "001) more effective than placebo, but not significantly so when the dosage level was halved." | 2.65 | A three-part controlled study of trimebutine in the treatment of irritable colon syndrome. ( Lüttecke, K, 1980) |
| "These findings suggest that mebeverine, in the initial dosing period, has a normalizing effect in the small bowel in IBS, enhancing contractile activity in a similar fashion to 'prokinetic' agents, as well as producing alterations in motor activity consistent with an 'antispasmodic' effect." | 1.29 | Mebeverine alters small bowel motility in irritable bowel syndrome. ( Bak, YT; Evans, PR; Kellow, JE, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ritchie, JA | 1 |
| Truelove, SC | 1 |
| Secco, GB | 1 |
| Di Somma, C | 1 |
| Arnulfo, G | 1 |
| Ricci, C | 1 |
| Prout, BJ | 1 |
| Haslam, DA | 1 |
| Lüttecke, K | 1 |
| Bilger, J | 1 |
| Pfister, H | 1 |
| Van Outryve, M | 1 |
| Mayeur, S | 1 |
| Meeus, MA | 1 |
| Rosillon, D | 1 |
| Hendrickx, B | 1 |
| Ceuppens, M | 1 |
| Evans, PR | 1 |
| Bak, YT | 1 |
| Kellow, JE | 1 |
| Jones, RH | 1 |
| Holtmann, G | 1 |
| Rodrigo, L | 1 |
| Ehsanullah, RS | 1 |
| Crompton, PM | 1 |
| Jacques, LA | 1 |
| Mills, JG | 1 |
| Lu, CL | 1 |
| Chen, CY | 1 |
| Chang, FY | 1 |
| Chang, SS | 1 |
| Kang, LJ | 1 |
| Lu, RH | 1 |
| Lee, SD | 1 |
| Gilbody, JS | 1 |
| Fletcher, CP | 1 |
| Hughes, IW | 1 |
| Kidman, SP | 1 |
| Eisenburg, J | 1 |
| Kruis, W | 2 |
| Schüssler, P | 2 |
| Weinzierl, M | 2 |
| Chapman, ND | 1 |
| Grillage, MG | 1 |
| Mazumder, R | 1 |
| Atkinson, SN | 1 |
| Holl, J | 1 |
| Tudor, GJ | 1 |
12 trials available for mebeverine and Colonic Diseases, Functional
| Article | Year |
|---|---|
Comparison of various treatments for irritable bowel syndrome.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Dietary Fiber; Drug | 1980 |
[Controlled clinical study of the action of mebeverine hydrochloride in the treatment of irritable colon].
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Dose-Response Relationship, Dru | 1983 |
The treatment of irritable bowel syndrome. Two doses of mebeverine compared.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind Method | 1983 |
A three-part controlled study of trimebutine in the treatment of irritable colon syndrome.
Topics: Adult; Aged; Benzoates; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind Method; | 1980 |
A double-blind crossover comparison study of the safety and efficacy of mebeverine with mebeverine sustained release in the treatment of irritable bowel syndrome.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Colonic Diseases, Functional; Cross-Over | 1995 |
Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients.
Topics: Adolescent; Adult; Carbolines; Colonic Diseases, Functional; Double-Blind Method; Female; Humans; Pa | 1999 |
Effect of a calcium channel blocker and antispasmodic in diarrhoea-predominant irritable bowel syndrome.
Topics: Calcium Channel Blockers; Colonic Diseases, Functional; Diarrhea; Female; Gastrointestinal Motility; | 2000 |
Comparison of two different formulations of mebeverine hydrochloride in irritable bowel syndrome.
Topics: Adolescent; Adult; Aged; Colonic Diseases, Functional; Delayed-Action Preparations; Double-Blind Met | 2000 |
[The irritable colon syndrome. New therapeutic possibilities in the treatment of a frequent syndrome].
Topics: Adolescent; Adult; Benzoates; Blood Coagulation; Colonic Diseases, Functional; Drug Evaluation; Fema | 1978 |
A comparison of mebeverine with high-fibre dietary advice and mebeverine plus ispaghula in the treatment of irritable bowel syndrome: an open, prospectively randomised, parallel group study.
Topics: Adolescent; Adult; Aged; Colonic Diseases, Functional; Dietary Fiber; Drug Therapy, Combination; Fem | 1990 |
Comparison of the therapeutic effect of wheat bran, mebeverine and placebo in patients with the irritable bowel syndrome.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Dietary Fiber; Female; Humans; | 1986 |
A general practice study to compare alverine citrate with mebeverine hydrochloride in the treatment of irritable bowel syndrome.
Topics: Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind Method; Female; Hu | 1986 |
3 other studies available for mebeverine and Colonic Diseases, Functional
| Article | Year |
|---|---|
The irritable bowel and ectopic pregnancy: a connection?
Topics: Adult; Colonic Diseases, Functional; Female; Humans; Parasympatholytics; Phenethylamines; Pregnancy; | 1984 |
[Treatment of irritable colon with Duspatal in ambulatory care].
Topics: Adolescent; Adult; Aged; Child; Colonic Diseases, Functional; Female; Humans; Male; Middle Aged; Phe | 1981 |
Mebeverine alters small bowel motility in irritable bowel syndrome.
Topics: Administration, Oral; Adult; Colonic Diseases, Functional; Female; Gastrointestinal Motility; Humans | 1996 |