Page last updated: 2024-10-30

mebeverine and Colitis, Mucous

mebeverine has been researched along with Colitis, Mucous in 29 studies

mebeverine: RN given refers to parent cpd; structure

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to examine whether pentoxifylline, a competitive nonselective phosphodiesterase inhibitor, is useful in alleviating abdominal pain in IBS patients treated with mebeverine."9.51Pentoxifylline, a nonselective phosphodiesterase inhibitor, in adjunctive therapy in patients with irritable bowel syndrome treated with mebeverine. ( Abd-Elsalam, SM; Bahaa, MM; El-Haggar, SM; Hegazy, SK, 2022)
"CBT in addition to mebeverine seems to have reasonable cost-effectiveness in the short-term treatment of irritable bowel syndrome, but not beyond 3 months."9.13Cost-effectiveness of cognitive behaviour therapy in addition to mebeverine for irritable bowel syndrome. ( Chalder, T; Darnley, S; Jones, R; Kennedy, T; Knapp, M; McCrone, P; Seed, P, 2008)
"We evaluated the efficacy and tolerability of mebeverine, a musculotropic antispasmodic agent, in irritable bowel syndrome (IBS) and compared its usual dosages by meta-analysis."8.86A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome. ( Abdollahi, M; Darvish-Damavandi, M; Nikfar, S, 2010)
" The aim of this study was to examine whether pentoxifylline, a competitive nonselective phosphodiesterase inhibitor, is useful in alleviating abdominal pain in IBS patients treated with mebeverine."5.51Pentoxifylline, a nonselective phosphodiesterase inhibitor, in adjunctive therapy in patients with irritable bowel syndrome treated with mebeverine. ( Abd-Elsalam, SM; Bahaa, MM; El-Haggar, SM; Hegazy, SK, 2022)
"To examine predictors of treatment outcome in IBS-patients who participated in a randomized controlled trial in primary care, where 149 irritable bowel syndrome (IBS) patients were randomized to mebeverine hydrochloride (n=77) or mebeverine+cognitive behavior therapy (CBT) (n=72)."5.14Predictors of treatment outcome after cognitive behavior therapy and antispasmodic treatment for patients with irritable bowel syndrome in primary care. ( Chalder, T; Darnley, S; Jones, R; Kennedy, T; Reme, SE, 2010)
"CBT in addition to mebeverine seems to have reasonable cost-effectiveness in the short-term treatment of irritable bowel syndrome, but not beyond 3 months."5.13Cost-effectiveness of cognitive behaviour therapy in addition to mebeverine for irritable bowel syndrome. ( Chalder, T; Darnley, S; Jones, R; Kennedy, T; Knapp, M; McCrone, P; Seed, P, 2008)
"149 patients with moderate or severe irritable bowel syndrome resistant to the antispasmodic mebeverine."5.11Cognitive behaviour therapy in addition to antispasmodic treatment for irritable bowel syndrome in primary care: randomised controlled trial. ( Chalder, T; Darnley, S; Jones, R; Kennedy, T; Seed, P; Wessely, S, 2005)
"We evaluated the efficacy and tolerability of mebeverine, a musculotropic antispasmodic agent, in irritable bowel syndrome (IBS) and compared its usual dosages by meta-analysis."4.86A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome. ( Abdollahi, M; Darvish-Damavandi, M; Nikfar, S, 2010)
" We performed an in-depth case study on mebeverine, a drug prescribed to patients with irritable bowel syndrome, to explore this hypothesis."3.74Health technology assessment and ill-structured problems: a case study concerning the drug mebeverine. ( Grin, J; Moret-Hartman, M; van der Wilt, GJ, 2007)
"Patients identified at community pharmacies, using mebeverine as a proxy for IBS, were administered a questionnaire regarding (1) the Rome II criteria for IBS, (2) predominant type of stool during complaints, (3) severity of symptoms (abdominal pain and discomfort), (4) generic and disease-specific quality of life, (5) current health status (utilities), and (6) loss of productivity."3.73Quality of life of patients with irritable bowel syndrome is low compared to others with chronic diseases. ( Goettsch, WG; Herings, RM; Smout, AJ; ten Berg, MJ; van den Boom, G, 2006)
"Mebeverine is a musculotropic agent that potently blocks intestinal peristalsis."2.50Role of antispasmodics in the treatment of irritable bowel syndrome. ( Annaházi, A; Róka, R; Rosztóczy, A; Wittmann, T, 2014)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (41.38)29.6817
2010's16 (55.17)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
El-Haggar, SM1
Hegazy, SK1
Abd-Elsalam, SM1
Bahaa, MM1
Nguyen, TT1
Dau, DT1
Nguyen, DC1
Nguyen, HT1
Ngo, PT1
Nguyen, TQ1
Han, B1
Hoang, BX1
Everitt, H2
Moss-Morris, R2
Sibelli, A2
Tapp, L2
Coleman, N1
Yardley, L2
Smith, P1
Little, P1
Sahib, AS1
Tonkin-Crine, S1
Bishop, FL1
Ellis, M1
Rahman, MZ1
Ahmed, DS1
Mahmuduzzaman, M1
Rahman, MA1
Chowdhury, MS1
Barua, R1
Ishaque, SM1
Annaházi, A1
Róka, R1
Rosztóczy, A1
Wittmann, T1
Hou, X1
Chen, S1
Zhang, Y1
Sha, W1
Yu, X1
Elsawah, H1
Afifi, AF1
El-Khayat, HR1
Nouh, A1
Hassan, MF1
Fatah, AA1
Rucker Joerg, I1
Sánchez Núñez, JM1
Osthoff Rueda, R1
Jurkowska, G1
Walczak, M1
Malecka-Panas, E1
Linke, K1
Hartleb, M1
Janssen-van Solingen, G1
Dumitrascu, DL1
Chira, A1
Bataga, S1
Diculescu, M1
Drug, V1
Gheorghe, C1
Goldis, A1
Nedelcu, L1
Porr, PJ1
Sporea, I1
Dance, A1
Heldwein, W1
Eisenlohr, H1
Kapoor, S1
Darvish-Damavandi, M1
Nikfar, S1
Abdollahi, M1
Reme, SE2
Kennedy, T4
Jones, R4
Darnley, S5
Chalder, T5
Everitt, HA1
Moss-Morris, RE1
Coleman, NS1
Smith, PW1
Little, PS1
Stahl, D1
Mönnikes, H1
Lee, KJ1
Kim, NY1
Kwon, JK1
Huh, KC1
Lee, OY1
Lee, JS1
Choi, SC1
Sohn, CI1
Myung, SJ1
Park, HJ1
Choi, MK1
Bak, YT1
Rhee, PL1
Clavé, P1
Goettsch, WG2
van den Boom, G2
Breekveldt-Postma, NS1
Smout, AJ2
Herings, RM2
Seed, P2
Wessely, S2
Enck, P1
Klosterhalfen, S1
Kruis, W1
Müller-Lissner, S1
ten Berg, MJ1
Kennedy, TM1
McCrone, P2
Knapp, M2
Jones, RH1
Mearin, F1
Moret-Hartman, M1
van der Wilt, GJ1
Grin, J1
Andresen, V1
Montori, VM1
Keller, J1
West, CP1
Layer, P1
Camilleri, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Management of Irritable Bowel Syndrome in Primary Care: Feasibility Randomised Controlled Trial of Mebeverine, Methylcellulose, Placebo and a Patient Self-management Cognitive Behavioural Therapy Website. (MIBS Trial)[NCT00934973]Phase 4135 participants (Actual)Interventional2010-04-30Completed
Sexual Dysfunction, Quality of Life and Visceral Hyperalgesia in Women With Irritable Bowel Syndrome[NCT04716738]20 participants (Anticipated)Observational [Patient Registry]2023-02-01Not yet recruiting
Persistent Physical Symptoms Reduction Intervention: a Systems Change and Evaluation (PRINCE) - Integrated GP Care for Persistent Physical Symptoms: a Feasibility & Cluster Randomised Controlled Trial[NCT02444520]161 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for mebeverine and Colitis, Mucous

ArticleYear
Role of antispasmodics in the treatment of irritable bowel syndrome.
    World journal of gastroenterology, 2014, May-28, Volume: 20, Issue:20

    Topics: Abdominal Pain; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal

2014
The use of mebeverine in irritable bowel syndrome. A Position paper of the Romanian Society of Neurogastroenterology based on evidence.
    Journal of gastrointestinal and liver diseases : JGLD, 2014, Volume: 23, Issue:4

    Topics: Drug Therapy, Combination; Evidence-Based Medicine; Gastroenterology; Gastrointestinal Agents; Human

2014
[Irritable bowel syndrome-an unbeloved problem].
    MMW Fortschritte der Medizin, 2008, Mar-27, Volume: 150, Issue:13

    Topics: Antidepressive Agents; Antidiarrheals; Cholinergic Antagonists; Colonoscopy; Diagnosis, Differential

2008
A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome.
    World journal of gastroenterology, 2010, Feb-07, Volume: 16, Issue:5

    Topics: Anticonvulsants; Databases, Factual; Female; Humans; Irritable Bowel Syndrome; Male; Parasympatholyt

2010
Quality of life in patients with irritable bowel syndrome.
    Journal of clinical gastroenterology, 2011, Volume: 45 Suppl

    Topics: Aged; Carbolines; Constipation; Diarrhea; Female; Gastrointestinal Agents; Health Status; Humans; Ir

2011
[Drug treatment of irritable bowel syndrome: an unmet need].
    Gastroenterologia y hepatologia, 2007, Volume: 30, Issue:3

    Topics: Abdominal Pain; Analgesics; Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Controlled

2007
Effects of 5-hydroxytryptamine (serotonin) type 3 antagonists on symptom relief and constipation in nonconstipated irritable bowel syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:5

    Topics: Administration, Oral; Carbazoles; Carbolines; Constipation; Diarrhea; Dose-Response Relationship, Dr

2008

Trials

12 trials available for mebeverine and Colitis, Mucous

ArticleYear
Pentoxifylline, a nonselective phosphodiesterase inhibitor, in adjunctive therapy in patients with irritable bowel syndrome treated with mebeverine.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Drug Therapy, Combination; Female; Humans; Irritabl

2022
Management of irritable bowel syndrome in primary care: the results of an exploratory randomised controlled trial of mebeverine, methylcellulose, placebo and a self-management website.
    BMC gastroenterology, 2013, Apr-21, Volume: 13

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Follow-Up Studies; Humans; Internet; Irritable Bowe

2013
Treatment of irritable bowel syndrome using a selected herbal combination of Iraqi folk medicines.
    Journal of ethnopharmacology, 2013, Jul-30, Volume: 148, Issue:3

    Topics: Adult; Cyperus; Female; Gastrointestinal Agents; Humans; Iraq; Irritable Bowel Syndrome; Male; Medic

2013
Exploring patients' views of a cognitive behavioral therapy-based website for the self-management of irritable bowel syndrome symptoms.
    Journal of medical Internet research, 2013, Sep-03, Volume: 15, Issue:9

    Topics: Adult; Cognitive Behavioral Therapy; Female; Humans; Internet; Irritable Bowel Syndrome; Male; Methy

2013
Comparative efficacy and safety of trimebutine versus mebeverine in the treatment of irritable bowel syndrome.
    Mymensingh medical journal : MMJ, 2014, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Bangladesh; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pain Mea

2014
Predictors of treatment outcome after cognitive behavior therapy and antispasmodic treatment for patients with irritable bowel syndrome in primary care.
    Journal of psychosomatic research, 2010, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Humans; Irritabl

2010
Management of irritable bowel syndrome in primary care: feasibility randomised controlled trial of mebeverine, methylcellulose, placebo and a patient self-management cognitive behavioural therapy website. (MIBS trial).
    BMC gastroenterology, 2010, Nov-18, Volume: 10

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Humans; Internet; Irritable Bowel Syndrome; Methylc

2010
Mediators of change in cognitive behaviour therapy and mebeverine for irritable bowel syndrome.
    Psychological medicine, 2011, Volume: 41, Issue:12

    Topics: Adolescent; Adult; Anxiety; Cognitive Behavioral Therapy; Combined Modality Therapy; Humans; Irritab

2011
Efficacy of ramosetron in the treatment of male patients with irritable bowel syndrome with diarrhea: a multicenter, randomized clinical trial, compared with mebeverine.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Benzimidazoles; Diarrhea; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pa

2011
Cognitive behaviour therapy in addition to antispasmodic treatment for irritable bowel syndrome in primary care: randomised controlled trial.
    BMJ (Clinical research ed.), 2005, Aug-20, Volume: 331, Issue:7514

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Combined Modality Therapy; Humans; Irritable Bowel

2005
Cognitive behavioural therapy in addition to antispasmodic therapy for irritable bowel syndrome in primary care: randomised controlled trial.
    Health technology assessment (Winchester, England), 2006, Volume: 10, Issue:19

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Humans; Irritabl

2006
Cost-effectiveness of cognitive behaviour therapy in addition to mebeverine for irritable bowel syndrome.
    European journal of gastroenterology & hepatology, 2008, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Cognitive Behavioral Therapy; Combined Modality Therapy; Cost of

2008

Other Studies

10 other studies available for mebeverine and Colitis, Mucous

ArticleYear
Effects of Trang Phuc Linh Plus-Food Supplement on Irritable Bowel Syndrome Induced by Mustard Oil.
    Journal of medicinal food, 2017, Volume: 20, Issue:4

    Topics: Animals; Colitis; Colon; Dietary Supplements; Drug Combinations; Female; Gastrointestinal Motility;

2017
Quality of life in patients with Irritable Bowel Syndrome (IBS), assessed using the IBS-Quality of Life (IBS-QOL) measure after 4 and 8 weeks of treatment with mebeverine hydrochloride or pinaverium bromide: results of an international prospective observa
    Clinical drug investigation, 2014, Volume: 34, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; China; Cohort Studies; Drug Administration Schedule; Egypt; Humans;

2014
Transit time.
    Nature, 2016, 05-19, Volume: 533, Issue:7603

    Topics: Anti-Bacterial Agents; Biofeedback, Psychology; Carbolines; Colitis; Diet; Dysentery; Dyspepsia; Egy

2016
Psychological associations of irritable bowel syndrome besides panic disorder: an often overlooked reality.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Drug Therapy, Combina

2009
Treatment of IBS-D with 5-HT3 receptor antagonists vs spasmolytic agents: similar therapeutical effects from heterogeneous pharmacological targets.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:12

    Topics: Benzimidazoles; Diarrhea; Humans; Irritable Bowel Syndrome; Male; Parasympatholytics; Phenethylamine

2011
Treatment patterns and health care costs of mebeverine-treated IBS patients: a case-control study.
    Pharmacoepidemiology and drug safety, 2004, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Cathartics; Health Care Costs; Hospitalization; Human

2004
[Determination of placebo effect in irritable bowel syndrome].
    Deutsche medizinische Wochenschrift (1946), 2005, Aug-26, Volume: 130, Issue:34-35

    Topics: Adult; Analysis of Variance; Data Interpretation, Statistical; Dietary Fiber; Double-Blind Method; F

2005
"My patients are the sickest".
    European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:5

    Topics: Humans; Irritable Bowel Syndrome; Parasympatholytics; Patient Acceptance of Health Care; Phenethylam

2006
Quality of life of patients with irritable bowel syndrome is low compared to others with chronic diseases.
    European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:5

    Topics: Abdominal Pain; Chronic Disease; Constipation; Cost of Illness; Diarrhea; Female; Health Status; Hea

2006
Health technology assessment and ill-structured problems: a case study concerning the drug mebeverine.
    International journal of technology assessment in health care, 2007,Summer, Volume: 23, Issue:3

    Topics: Governing Board; Health Policy; Humans; Irritable Bowel Syndrome; Organizational Case Studies; Paras

2007