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mebendazole and Toxocariasis

mebendazole has been researched along with Toxocariasis in 21 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Toxocariasis: Infection by round worms of the genus TOXOCARA, usually found in wild and domesticated cats and dogs and foxes, except for the larvae, which may produce visceral and ocular larva migrans in man.

Research Excerpts

ExcerptRelevanceReference
"An open randomized study was carried out to assess the efficacy of diethylcarbamazine (DEC) and mebendazole (MBZ) across, respectively, 39 and 41 patients, all exhibiting clinical and biological features evocative of toxocariasis, together with a positive immunodiagnosis by Western blot using Toxocara larvae excretory-secretory antigens."9.08Comparative efficacy of diethylcarbamazine and mebendazole for the treatment of human toxocariasis. ( Magnaval, JF, 1995)
"We have studied the action of mebendazole on experimental murine toxocariasis using different formulations and vehicles."7.69Evaluation by larval recovery of mebendazole activity in experimental murine toxocariasis. ( Bardón, R; Cuéllar, C; Guillén, JL, 1995)
"The mebendazole action on experimental murine toxocariasis, using different formulations and vehicles, was studied by means of the detection of antibodies and immune complexes by ELISA."7.69Evaluation of mebendazole activity on experimental murine toxocariasis by immune complexes determination. ( Bardon, R; Cuellar, C; del Aguila, C; Guillen, JL, 1995)
"An open randomized study was carried out to assess the efficacy of diethylcarbamazine (DEC) and mebendazole (MBZ) across, respectively, 39 and 41 patients, all exhibiting clinical and biological features evocative of toxocariasis, together with a positive immunodiagnosis by Western blot using Toxocara larvae excretory-secretory antigens."5.08Comparative efficacy of diethylcarbamazine and mebendazole for the treatment of human toxocariasis. ( Magnaval, JF, 1995)
"Endemic parasitic infections in the United States are more frequent than is commonly perceived."2.49Childhood parasitic infections endemic to the United States. ( Barry, MA; Hotez, PJ; Weatherhead, JE; Woc-Colburn, L, 2013)
" the same grade of damage was reached when incubating for a longer period at a low dosage or for a shorter period in medium containing a high amount (10 or 100 micro g/ml) of flubendazole."1.32In vitro studies on the effects of flubendazole against Toxocara canis and Ascaris suum. ( Hanser, E; Hoeben, D; Mehlhorn, H; Vlaminck, K, 2003)
"Mebendazole was prescribed for one month at 25 mg/kg per body weight daily."1.30A case of presumed ocular toxocariasis in a 28-year old woman. ( Huh, S; Magnaval, JF; Park, I; Park, SP, 1999)
"Mebendazole was given to infected animals for 2 weeks beginning 5 weeks (prepatent) or 16 weeks (patent) after infection."1.28Eosinophil hyporesponse of jirds induced by microfilariae of Brugia pahangi. ( Fujita, K; Horii, Y; Kurokawa, K; Mori, A; Nakanishi, H; Oda, T; Ueda, M; Zaitsu, M, 1989)
"Toxocariasis is an infrequent disease which particularly affects children."1.27[Pleural effusion and Toxocara canis]. ( Bruart, J; Henneghien, C; Jonckheer, J; Remacle, P, 1987)
"A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats."1.26Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats. ( Guerrero, J; London, CE; McCall, JW; Michael, B; Newcomb, K; Pancari, G; Roberson, EL, 1981)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's8 (38.10)18.2507
2000's7 (33.33)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rostami, A1
Ma, G1
Wang, T1
Koehler, AV1
Hofmann, A1
Chang, BCH1
Macpherson, CN1
Gasser, RB1
Barry, MA1
Weatherhead, JE1
Hotez, PJ1
Woc-Colburn, L1
Niedworok, M1
Sordyl, B1
Borecka, A1
Gawor, J1
Małecka-Panas, E1
Hanser, E1
Mehlhorn, H1
Hoeben, D1
Vlaminck, K1
Auer, H1
Aspöck, H1
Dauriac-Le Masson, V1
Chochon, F1
Demeret, S1
Pierrot-Deseilligny, C1
Scheid, PL1
Georgi, E1
Dymon, M1
Papir, B1
Dutoit, E1
Poirriez, J1
Leclercq, P1
Vernes, A1
Fontaine, G1
London, CE1
Roberson, EL1
McCall, JW1
Guerrero, J1
Pancari, G1
Michael, B1
Newcomb, K1
Magnaval, JF2
Bardón, R2
Cuéllar, C3
Guillén, JL3
Kumar, J1
Kimm, J1
del Aguila, C1
Abdel Ghafar, AE1
Elkowrany, SE1
Salem, SA1
Menaisy, AA1
Fadel, WA1
Awara, WM1
Park, SP1
Huh, S1
Park, I1
Allemandou, M1
Krcméry, V1
Gould, I1
Sobota, K1
Spánik, S1
Fenoy, S1
Aguila, C1
Horii, Y1
Nakanishi, H1
Mori, A1
Zaitsu, M1
Ueda, M1
Kurokawa, K1
Oda, T1
Fujita, K1
Bruart, J1
Remacle, P1
Henneghien, C1
Jonckheer, J1

Reviews

4 reviews available for mebendazole and Toxocariasis

ArticleYear
Human toxocariasis - A look at a neglected disease through an epidemiological 'prism'.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2019, Volume: 74

    Topics: Adrenal Cortex Hormones; Albendazole; Anthelmintics; Drug Therapy, Combination; Humans; Mebendazole;

2019
Childhood parasitic infections endemic to the United States.
    Pediatric clinics of North America, 2013, Volume: 60, Issue:2

    Topics: Albendazole; Antiparasitic Agents; Black or African American; Chagas Disease; Child; Child, Preschoo

2013
[Nosology and epidemiology of human toxocarosis--the recent situation in Austria].
    Wiener klinische Wochenschrift, 2004, Volume: 116 Suppl 4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthelmin

2004
[Toxocara canis -- the hazard in the sandbox?].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2006, Volume: 25, Issue:2

    Topics: Adult; Age Factors; Albendazole; Animals; Anthelmintics; Anti-Inflammatory Agents; Antiparasitic Age

2006

Trials

1 trial available for mebendazole and Toxocariasis

ArticleYear
Comparative efficacy of diethylcarbamazine and mebendazole for the treatment of human toxocariasis.
    Parasitology, 1995, Volume: 110 ( Pt 5)

    Topics: Adult; Animals; Antibodies, Helminth; Blotting, Western; Cat Diseases; Cats; Diethylcarbamazine; Dog

1995

Other Studies

16 other studies available for mebendazole and Toxocariasis

ArticleYear
[Estimation of eosinophilia, immunoglobulin E and eosinophilic cationic protein concentration during the treatment of toxocariasis].
    Wiadomosci parazytologiczne, 2008, Volume: 54, Issue:3

    Topics: Adolescent; Animals; Antiparasitic Agents; Biomarkers; Child; Child, Preschool; Eosinophil Cationic

2008
In vitro studies on the effects of flubendazole against Toxocara canis and Ascaris suum.
    Parasitology research, 2003, Volume: 89, Issue:1

    Topics: Animals; Antinematodal Agents; Ascariasis; Ascaris suum; Dogs; Dose-Response Relationship, Drug; Fem

2003
Toxocara canis meningomyelitis.
    Journal of neurology, 2005, Volume: 252, Issue:10

    Topics: Adult; Animals; Antibodies, Helminth; Antinematodal Agents; Enzyme-Linked Immunosorbent Assay; Eosin

2005
[Effect of anthelmintic therapy supplemented with glucan in experimental toxocarosis].
    Wiadomosci parazytologiczne, 2004, Volume: 50, Issue:3

    Topics: Albendazole; Animals; Anthelmintics; beta-Glucans; Brain; Diethylcarbamazine; Drug Therapy, Combinat

2004
[Value of flubendazole in the treatment of toxocariasis].
    Presse medicale (Paris, France : 1983), 1983, Oct-29, Volume: 12, Issue:38

    Topics: Antinematodal Agents; Ascariasis; Benzimidazoles; Child, Preschool; Humans; Male; Mebendazole; Toxoc

1983
Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.
    American journal of veterinary research, 1981, Volume: 42, Issue:7

    Topics: Ancylostomiasis; Animals; Ascariasis; Benzimidazoles; Cat Diseases; Cats; Feces; Mebendazole; Taenia

1981
Evaluation by larval recovery of mebendazole activity in experimental murine toxocariasis.
    International journal for parasitology, 1995, Volume: 25, Issue:5

    Topics: Animals; Brain; Drug Administration Schedule; Larva; Liver; Lung; Male; Mebendazole; Mice; Mice, Inb

1995
MR in Toxocara canis myelopathy.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:10

    Topics: Animals; Dexamethasone; Drug Therapy, Combination; Female; Magnetic Resonance Imaging; Mebendazole;

1994
Evaluation of mebendazole activity on experimental murine toxocariasis by immune complexes determination.
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1995, Volume: 42, Issue:4

    Topics: Animals; Antibodies, Helminth; Antigen-Antibody Complex; Antinematodal Agents; Mebendazole; Mice; Mi

1995
Effect of some parasitic infection on neurotransmitters in the brain of experimentally infected mice before and after treatment.
    Journal of the Egyptian Society of Parasitology, 1996, Volume: 26, Issue:2

    Topics: Animals; Brain; Dopamine; Mebendazole; Mice; Neurotransmitter Agents; Norepinephrine; Parasitic Dise

1996
A case of presumed ocular toxocariasis in a 28-year old woman.
    Korean journal of ophthalmology : KJO, 1999, Volume: 13, Issue:2

    Topics: Adult; Animals; Antibodies, Helminth; Antinematodal Agents; Cryotherapy; Diagnosis, Differential; En

1999
[Toxocariasis].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:12

    Topics: Antinematodal Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Mebend

2001
Two cases of disseminated toxocariasis in compromised hosts successfully treated with mebendazole.
    Chemotherapy, 1992, Volume: 38, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Animals; Female; Humans; Immunocompromised Host; Male; Mebendazole;

1992
Evaluation of chemotherapy in experimental toxocarosis by determination of specific immune complexes.
    Journal of helminthology, 1990, Volume: 64, Issue:4

    Topics: Animals; Antibodies, Helminth; Antigen-Antibody Complex; Enzyme-Linked Immunosorbent Assay; Mebendaz

1990
Eosinophil hyporesponse of jirds induced by microfilariae of Brugia pahangi.
    The American journal of tropical medicine and hygiene, 1989, Volume: 41, Issue:2

    Topics: Animals; Brugia; Chronic Disease; Eosinophils; Filariasis; Gerbillinae; Male; Mebendazole; Microfila

1989
[Pleural effusion and Toxocara canis].
    Revue des maladies respiratoires, 1987, Volume: 4, Issue:1

    Topics: Antigens, Helminth; Ascariasis; Enzyme-Linked Immunosorbent Assay; Eosinophilia; Female; Humans; Meb

1987