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mebendazole and Schistosoma mansoni Infection

mebendazole has been researched along with Schistosoma mansoni Infection in 13 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
" In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children."9.15The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011)
"This study is a trial to demonstrate the effect of the broad spectrum anthelmintic drug flubendazole (methyl 5-(p-fluoro-benzoyl)-2-benzimidazolecarbamate, CAS 31430-15-6), a mebendazole derivative, together with praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in murine schistosomiasis mansoni."7.72Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection. ( Guirguis, F; Nessim, NG; William, S, 2003)
" In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-transmitted helminthiasis (STH) in school-aged children, no specific acceptability or safety studies have been published on this drug combination in younger children."5.15The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. ( Kabatereine, NB; Namwanje, H; Olsen, A, 2011)
"This study is a trial to demonstrate the effect of the broad spectrum anthelmintic drug flubendazole (methyl 5-(p-fluoro-benzoyl)-2-benzimidazolecarbamate, CAS 31430-15-6), a mebendazole derivative, together with praziquantel (CAS 55268-74-1, EMBAY 8440, Biltricide) in murine schistosomiasis mansoni."3.72Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection. ( Guirguis, F; Nessim, NG; William, S, 2003)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Ejigu, K1
Hailu, T1
Alemu, M1
Ndombi, EM1
Abudho, B1
Kittur, N1
Carter, JM1
Korir, H1
Riner, DK1
Ochanda, H1
Lee, YM1
Secor, WE1
Karanja, DM1
Colley, DG1
Favre, TC1
Pereira, AP1
Beck, LC1
Galvão, AF1
Pieri, OS1
Namwanje, H1
Kabatereine, NB1
Olsen, A1
Hodges, MH1
Dada, N1
Warmsley, A1
Paye, J1
Bangura, MM1
Nyorkor, E1
Sonnie, M1
Zhang, Y1
Legesse, M1
Erko, B1
Medhin, G1
William, S2
Guirguis, F1
Nessim, NG2
Engels, D1
Ndoricimpa, J1
Gryseels, B1
Abdel Ghafar, AE1
Elkowrany, SE1
Salem, SA1
Menaisy, AA1
Fadel, WA1
Awara, WM1
Hassan, SI1
el-Baz, H1
Zwingenberger, K1
Hohmann, A1
de Brito, MC1
Ritter, M1
al-Waili, NS1
Katz, N1
Araújo, N1

Trials

3 trials available for mebendazole and Schistosoma mansoni Infection

ArticleYear
School-based and community-based actions for scaling-up diagnosis and treatment of schistosomiasis toward its elimination in an endemic area of Brazil.
    Acta tropica, 2015, Volume: 149

    Topics: Adolescent; Animals; Anthelmintics; Brazil; Child; Community Health Services; Community Participatio

2015
The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda.
    Parasitology, 2011, Volume: 138, Issue:12

    Topics: Animals; Anthelmintics; Ascariasis; Ascaris lumbricoides; Child, Preschool; Drug Therapy, Combinatio

2011
Efficacy of alebendazole and mebendazole in the treatment of Ascaris and Trichuris infections.
    Ethiopian medical journal, 2002, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albendazole; Animals; Anthelmintics; Ascariasis; Ascaris

2002

Other Studies

10 other studies available for mebendazole and Schistosoma mansoni Infection

ArticleYear
Efficacy of Mebendazole and Praziquantel against Soil-Transmitted Helminths and
    BioMed research international, 2021, Volume: 2021

    Topics: Adolescent; Animals; Child; Ethiopia; Female; Geography; Helminthiasis; Helminths; Humans; Male; Meb

2021
Effect of four rounds of annual school-wide mass praziquantel treatment for schistosoma mansoni control on schistosome-specific immune responses.
    Parasite immunology, 2018, Volume: 40, Issue:6

    Topics: Adolescent; Animals; Anthelmintics; Antibodies, Helminth; Child; Cross-Sectional Studies; Cytokines;

2018
Mass drug administration significantly reduces infection of Schistosoma mansoni and hookworm in school children in the national control program in Sierra Leone.
    BMC infectious diseases, 2012, Jan-22, Volume: 12

    Topics: Adolescent; Ancylostomatoidea; Animals; Anthelmintics; Child; Drug Therapy; Feces; Female; Hookworm

2012
Effect of simultaneous and/or consecutive administration of the broad spectrum anthelmintic flubendazole together with praziquantel in experimental Schistosoma mansoni infection.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:7

    Topics: Animals; Drug Therapy, Combination; Female; Granuloma; Liver; Male; Mebendazole; Mice; Parasite Egg

2003
Schistosomiasis mansoni in Burundi: progress in its control since 1985.
    Bulletin of the World Health Organization, 1993, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Animals; Anthelmintics; Burundi; Child; Humans; Levamisole; Mebendazole; Niclosam

1993
Effect of some parasitic infection on neurotransmitters in the brain of experimentally infected mice before and after treatment.
    Journal of the Egyptian Society of Parasitology, 1996, Volume: 26, Issue:2

    Topics: Animals; Brain; Dopamine; Mebendazole; Mice; Neurotransmitter Agents; Norepinephrine; Parasitic Dise

1996
Effect of the broad spectrum anthelmintic drug flubendazole upon Schistosoma mansoni experimentally infected mice.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:12

    Topics: Animals; Enzyme-Linked Immunosorbent Assay; Female; Granuloma; Liver; Male; Mebendazole; Mice; Schis

2000
Impaired balance of interleukin-4 and interferon-gamma production in infections with Schistosoma mansoni and intestinal nematodes.
    Scandinavian journal of immunology, 1991, Volume: 34, Issue:2

    Topics: Female; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Intestines; Male; Mebendazole; Ne

1991
Effects of mebendazole on patients infected with Schistosoma mansoni and S. haematobium: preliminary study.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Adult; Child; Humans; Mebendazole; Schistosomiasis haematobia; Schistosomiasis mansoni

1988
Mebendazole in the treatment of mice experimentally infected with Schistosoma mansoni.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:6

    Topics: Animals; Female; Mebendazole; Mice; Schistosomiasis mansoni

1988