mebendazole has been researched along with Precursor T-Cell Lymphoblastic Leukemia-Lymphoma in 2 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma: A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mebendazole (MBZ) is a tubulin-suppressive antihelmintic agent with low toxicity, which has been repurposed to treat different types of tumors." | 1.56 | Mebendazole is a potent inhibitor to chemoresistant T cell acute lymphoblastic leukemia cells. ( Lou, K; Ma, H; Song, X; Wang, W; Wang, X; Xu, H; Zhou, X, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, C | 1 |
| Touzart, A | 1 |
| Simonin, M | 1 |
| Tran-Quang, C | 1 |
| Hypolite, G | 1 |
| Latiri, M | 1 |
| Andrieu, GP | 1 |
| Balducci, E | 1 |
| Dourthe, MÉ | 1 |
| Goyal, A | 1 |
| Huguet, F | 1 |
| Petit, A | 1 |
| Ifrah, N | 1 |
| Baruchel, A | 1 |
| Dombret, H | 1 |
| Macintyre, E | 1 |
| Plass, C | 1 |
| Ghysdael, J | 1 |
| Boissel, N | 1 |
| Asnafi, V | 1 |
| Wang, X | 1 |
| Lou, K | 1 |
| Song, X | 1 |
| Ma, H | 1 |
| Zhou, X | 1 |
| Xu, H | 1 |
| Wang, W | 1 |
2 other studies available for mebendazole and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL.
Topics: Basic Helix-Loop-Helix Transcription Factors; Humans; Mebendazole; Precursor T-Cell Lymphoblastic Le | 2023 |
Mebendazole is a potent inhibitor to chemoresistant T cell acute lymphoblastic leukemia cells.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumo | 2020 |