mebendazole has been researched along with Polyploid in 3 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ability of flubendazole to induce polyploidy may be part of the mechanism by which this compound induces morphological transformation." | 1.29 | Induction of chromosomal aberrations, cytotoxicity, and morphological transformation in mammalian cells by the antiparasitic drug flubendazole and the antineoplastic drug harringtonine. ( Cerepnalkoski, L; Dews, M; Huang, N; Landolph, JR; Nwankwo, JO, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kipper, FC | 1 |
| Silva, AO | 1 |
| Marc, AL | 1 |
| Confortin, G | 1 |
| Junqueira, AV | 1 |
| Neto, EP | 1 |
| Lenz, G | 1 |
| Huang, N | 1 |
| Cerepnalkoski, L | 1 |
| Nwankwo, JO | 1 |
| Dews, M | 1 |
| Landolph, JR | 1 |
| Elhajouji, A | 1 |
| Cunha, M | 1 |
| Kirsch-Volders, M | 1 |
3 other studies available for mebendazole and Polyploid
| Article | Year |
|---|---|
Vinblastine and antihelmintic mebendazole potentiate temozolomide in resistant gliomas.
Topics: Anthelmintics; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; Drug Resistance, Neopl | 2018 |
Induction of chromosomal aberrations, cytotoxicity, and morphological transformation in mammalian cells by the antiparasitic drug flubendazole and the antineoplastic drug harringtonine.
Topics: Animals; Antinematodal Agents; Antineoplastic Agents; Cell Division; Cell Line, Transformed; Cell Su | 1994 |
Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay.
Topics: Benzimidazoles; Carbamates; Colchicine; Female; Humans; Leukocyte Count; Leukocytes, Mononuclear; Ma | 1998 |