mebendazole has been researched along with Ovine Diseases in 34 studies
Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flubendazole (FLBZ) is a poor water solubility broad-spectrum BZD methylcarbamate anthelmintic compound." | 2.77 | Exploring flubendazole formulations for use in sheep. Pharmacokinetic evaluation of a cyclodextrin-based solution. ( Alvarez, L; Ceballos, L; Lanusse, C; Moreno, L; Torrado, JJ, 2012) |
| "Mebendazole was 100 per cent effective against adult Ostertagia species and T colubriformis, but reduced the numbers of adult C curticei by only 39 per cent, S papillosus by 58 per cent, H contortus by 76 per cent, and fifth stage larvae of Oesophagostomum species by 79 per cent and C ovina by 72 per cent." | 2.67 | Comparative efficacy of moxidectin and mebendazole against gastrointestinal nematodes in experimentally infected lambs. ( Bauer, C; Conraths, FJ, 1994) |
| "Thiabendazole was used more often (9 tests) than the other compounds." | 2.67 | Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962. ( Drudge, JH; Lyons, ET; Stamper, S; Tolliver, SC, 1993) |
| "Mebendazole was also highly effective (97." | 2.65 | Anthelmintic efficacy of mebendazole suspension against induced helminth infections in South African sheep and cattle. ( Guerrero, J; Newcomb, K; Van der Westhuizen, B, 1984) |
| "The aim of the present study is to explore the possibility to increase the efficacy of mebendazole (MBZ) against secondary cysts of Echinococcus granulosus harbored in mice by augmenting the solubility and bioavailability of the drug." | 1.38 | Enhanced bioavailability and cysticidal effect of three mebendazole-oil preparations in mice infected with secondary cysts of Echinococcus granulosus. ( Jiang, B; Liu, CS; Tao, Y; Wen, AD; Xue, J; Yao, JM; Zhang, HB, 2012) |
| "Flubendazole (FLBZ) is a broad spectrum benzimidazole methylcarbamate anthelmintic widely used in poultry and swine." | 1.32 | Integrated pharmacological assessment of flubendazole potential for use in sheep: disposition kinetics, liver metabolism and parasite diffusion ability. ( Alvarez, L; Bruni, SS; Lanusse, C; Moreno, L; Mottier, L; Virkel, G, 2004) |
| " This change was related to decreases in both the elimination from the pharmacokinetic compartment representing the reduced metabolite and the area under the curve of plasma metabolite concentration versus time." | 1.29 | Fasciola hepatica: mebendazole and thiabendazole pharmacokinetics in sheep. ( Alvinerie, M; Biro-Sauveur, B; Coulet, M; Galtier, P; Sutra, JF, 1994) |
| " The game were extremely willing to ingest the drug applied with feed, the dosing schedule being confirmed." | 1.29 | [Effect of flubendazole on Muellerius capillaris in mouflon]. ( Klecá ková, J; Lamka, J; Vondrejc, M, 1996) |
| " In the latter case, control was achieved by dosing either the ewes in the early part of the grazing season, or the lambs from June onwards." | 1.28 | Effectiveness of strategic anthelmintic dosing in controlling Haemonchus contortus infections in sheep in the United Kingdom. ( Hunt, KR; Quick, JM; Taylor, MA; Wilson, CA, 1991) |
| "Treatment with resorantel at 65 mg/kg or niclosamide at 50 mg/kg however, caused expulsion of the strobilae within 16--24 hours after treatment and at autopsy, lambs were free of scoleces of T." | 1.26 | The efficacy of anthelmintics against Thysaniezia giardi in South Africa. ( Davies, PV; Geyser, TL; Récio, M; Van Schalkwyk, PC, 1981) |
| "Fenbendazole was more effective against both strains following intra-ruminal administration." | 1.26 | The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole. ( Campbell, NJ; Hall, CA; Kelly, JD; Martin, IC; Thompson, HG; Whitlock, HV, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (41.18) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 7 (20.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stuchlíková, LR | 1 |
| Matoušková, P | 1 |
| Vokřál, I | 3 |
| Lamka, J | 6 |
| Szotáková, B | 5 |
| Sečkařová, A | 1 |
| Dimunová, D | 1 |
| Nguyen, LT | 1 |
| Várady, M | 3 |
| Skálová, L | 5 |
| Ceballos, L | 2 |
| Virkel, G | 2 |
| Elissondo, C | 1 |
| Canton, C | 1 |
| Canevari, J | 1 |
| Murno, G | 1 |
| Denegri, G | 1 |
| Lanusse, C | 3 |
| Alvarez, L | 3 |
| Prchal, L | 2 |
| Bártíková, H | 3 |
| Bečanová, A | 1 |
| Jirásko, R | 1 |
| Stuchlíková, L | 2 |
| Kubíček, V | 4 |
| Trejtnar, F | 1 |
| Scholes, SF | 1 |
| Reichel, R | 1 |
| Willmington, J | 1 |
| Daniel, R | 1 |
| Krízová, V | 2 |
| Moreno, L | 2 |
| Torrado, JJ | 1 |
| Liu, CS | 1 |
| Zhang, HB | 1 |
| Jiang, B | 1 |
| Yao, JM | 1 |
| Tao, Y | 1 |
| Xue, J | 1 |
| Wen, AD | 1 |
| Paksoy, Y | 1 |
| Odev, K | 1 |
| Sahin, M | 1 |
| Dik, B | 1 |
| Ergül, R | 1 |
| Arslan, A | 1 |
| Mottier, L | 1 |
| Bruni, SS | 1 |
| Jones, E | 1 |
| Arru, E | 1 |
| Leoni, A | 1 |
| Garippa, G | 1 |
| Garg, R | 1 |
| Kumar, RR | 1 |
| Yadav, CL | 2 |
| Banerjee, PS | 1 |
| Cvilink, V | 1 |
| Nobilis, M | 1 |
| Kubenová, M | 1 |
| Novotná, R | 1 |
| Gavelová, M | 1 |
| Van der Westhuizen, B | 1 |
| Newcomb, K | 1 |
| Guerrero, J | 1 |
| Gemmell, MA | 1 |
| Parmeter, SN | 1 |
| Sutton, RJ | 1 |
| Khan, N | 1 |
| Al-Dabagh, MA | 1 |
| Al-Moslih, MI | 1 |
| Verheyen, A | 1 |
| Shafik, MA | 1 |
| Al-Janabi, TA | 1 |
| Al-Rawas, AY | 1 |
| Ismail, MA | 1 |
| Fawzi, AH | 1 |
| Al-Ani, MS | 1 |
| Rassam, S | 1 |
| Van Schalkwyk, PC | 1 |
| Geyser, TL | 1 |
| Davies, PV | 1 |
| Récio, M | 1 |
| Vasilevich, FI | 1 |
| Abuladze, KI | 1 |
| Malakhov, AG | 1 |
| Chevis, RA | 3 |
| Galtier, P | 1 |
| Coulet, M | 1 |
| Sutra, JF | 1 |
| Biro-Sauveur, B | 1 |
| Alvinerie, M | 1 |
| Bauer, C | 1 |
| Conraths, FJ | 1 |
| Lyons, ET | 1 |
| Drudge, JH | 1 |
| Tolliver, SC | 1 |
| Stamper, S | 1 |
| Kumar, R | 1 |
| Uppal, RP | 1 |
| Verma, SP | 1 |
| Vondrejc, M | 1 |
| Klecá ková, J | 1 |
| Rahman, MS | 1 |
| Cornish, RA | 1 |
| Bryant, C | 1 |
| Zajícek, D | 1 |
| Márová, M | 1 |
| Zahradníková, W | 1 |
| Mamaev, NKh | 1 |
| Davudov, DM | 1 |
| Kelly, JD | 2 |
| Hall, CA | 1 |
| Whitlock, HV | 2 |
| Thompson, HG | 1 |
| Campbell, NJ | 1 |
| Martin, IC | 1 |
| Thienpont, D | 1 |
| Vanparijs, O | 1 |
| Niemegeers, C | 1 |
| Marsboom, R | 1 |
| Varga, I | 1 |
| Janisch, M | 1 |
| Taylor, MA | 2 |
| Hunt, KR | 2 |
| Wilson, CA | 2 |
| Quick, JM | 2 |
7 trials available for mebendazole and Ovine Diseases
| Article | Year |
|---|---|
A pharmacology-based comparison of the activity of albendazole and flubendazole against Echinococcus granulosus metacestode in sheep.
Topics: Albendazole; Animals; Anthelmintics; Area Under Curve; Echinococcosis; Echinococcus granulosus; Half | 2013 |
Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis.
Topics: Animals; Biotransformation; Haemonchiasis; Haemonchus; Liver; Male; Mebendazole; Sheep; Sheep Diseas | 2010 |
Exploring flubendazole formulations for use in sheep. Pharmacokinetic evaluation of a cyclodextrin-based solution.
Topics: Abomasum; Albendazole; Animals; Antinematodal Agents; Area Under Curve; Benzimidazoles; Body Fluids; | 2012 |
Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep.
Topics: Administration, Oral; Administration, Topical; Albendazole; Animals; Anthelmintics; Drug Resistance, | 2007 |
Anthelmintic efficacy of mebendazole suspension against induced helminth infections in South African sheep and cattle.
Topics: Administration, Oral; Animals; Benzimidazoles; Cattle; Cattle Diseases; Clinical Trials as Topic; Fe | 1984 |
Comparative efficacy of moxidectin and mebendazole against gastrointestinal nematodes in experimentally infected lambs.
Topics: Administration, Oral; Animals; Anthelmintics; Anti-Bacterial Agents; Female; Intestinal Diseases, Pa | 1994 |
Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.
Topics: Aging; Animals; Anthelmintics; Benzimidazoles; Cambendazole; Drug Combinations; Fenbendazole; Haemon | 1993 |
27 other studies available for mebendazole and Ovine Diseases
| Article | Year |
|---|---|
Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites.
Topics: Albendazole; Animals; Anthelmintics; Biochemical Phenomena; Biotransformation; Drug Resistance; Fema | 2018 |
Biotransformation of anthelmintics and the activity of drug-metabolizing enzymes in the tapeworm Moniezia expansa.
Topics: Albendazole; Alcohol Oxidoreductases; Animals; Anthelmintics; Biotransformation; Catalase; Cestoda; | 2015 |
Malformations including hemimelia and amelia in sheep.
Topics: Albendazole; Animals; Anthelmintics; Ectromelia; Female; Mebendazole; Pregnancy; Sheep; Sheep Diseas | 2008 |
Enhanced bioavailability and cysticidal effect of three mebendazole-oil preparations in mice infected with secondary cysts of Echinococcus granulosus.
Topics: Animals; Biological Availability; Echinococcosis, Hepatic; Echinococcus granulosus; Female; Mebendaz | 2012 |
The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics.
Topics: Animals; Anthelmintics; Drug Resistance; Haemonchiasis; Haemonchus; Mebendazole; Sheep; Sheep Diseas | 2012 |
Percutaneous sonographically guided treatment of hydatid cysts in sheep: direct injection of mebendazole and albendazole.
Topics: Albendazole; Animals; Antinematodal Agents; Antiprotozoal Agents; Echinococcosis, Hepatic; Injection | 2003 |
Integrated pharmacological assessment of flubendazole potential for use in sheep: disposition kinetics, liver metabolism and parasite diffusion ability.
Topics: Animals; Anthelmintics; Area Under Curve; Cestoda; Chromatography, High Pressure Liquid; Cross-Over | 2004 |
Withdrawal period for Ovitelmin S&C.
Topics: Animals; Antinematodal Agents; Consumer Product Safety; Drug Evaluation; Female; Male; Mebendazole; | 2005 |
Morphobiology of Echinococcus granulosus and therapeutic trials in sheep.
Topics: Albendazole; Animals; Antinematodal Agents; Echinococcosis; Echinococcus granulosus; Mebendazole; Sh | 1989 |
Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus.
Topics: Animals; Biotransformation; Haemonchiasis; Haemonchus; Mebendazole; Oxidoreductases; Sheep; Sheep Di | 2008 |
Effect of mebendazole against Echinococcus granulosus and Taenia hydatigena cysts in naturally infected sheep and relevance to larval tapeworm infections in man.
Topics: Animals; Benzimidazoles; Echinococcosis; Echinococcus; Female; Humans; Mebendazole; Pregnancy; Sheep | 1981 |
The effect of mebendazole on sheep hydatid cysts as demonstrated by electron microscopy.
Topics: Animals; Benzimidazoles; Echinococcosis, Hepatic; Echinococcosis, Pulmonary; Echinococcus; Female; M | 1981 |
The efficacy of anthelmintics against Thysaniezia giardi in South Africa.
Topics: Albendazole; Anilides; Animals; Anthelmintics; Benzimidazoles; Cambendazole; Mebendazole; Nematode I | 1981 |
[Functional and morphological state of the liver of lambs under therapy for Cysticercus tenuicollis infection].
Topics: Animals; Anthelmintics; Benzimidazoles; Cysticercosis; Drug Evaluation, Preclinical; Liver; Mebendaz | 1980 |
The speed of action of anthelmintics: mebendazole.
Topics: Animals; Benzimidazoles; Digestive System; Fascioliasis; Haemonchiasis; Mebendazole; Monieziasis; Sh | 1980 |
Fasciola hepatica: mebendazole and thiabendazole pharmacokinetics in sheep.
Topics: Administration, Oral; Animals; Fascioliasis; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Liv | 1994 |
Multiple anthelmintic resistance in Haemonchus contortus on a sheep farm in India.
Topics: Albendazole; Animal Husbandry; Animals; Anthelmintics; Benzimidazoles; Drug Resistance, Multiple; Fe | 1995 |
[Effect of flubendazole on Muellerius capillaris in mouflon].
Topics: Animals; Animals, Wild; Antinematodal Agents; Czech Republic; Mebendazole; Metastrongyloidea; Sheep; | 1996 |
Metabolic changes in some helminths from sheep treated with mebendazole.
Topics: Animals; Benzimidazoles; Candidiasis; Cestoda; Fasciola; Fascioliasis; Haemonchiasis; Haemonchus; He | 1977 |
[Efficacy of mebendazole in sheep experimentally invaded with larvae of Haemonchus contortus and Trichostrongylus colubriformis in relation to the results of clinical examination].
Topics: Animals; Benzimidazoles; Disease Models, Animal; Haemonchiasis; Mebendazole; Sheep; Sheep Diseases; | 1978 |
[Tetramisole granulate and Mebenvet against ovine Strongylata infections].
Topics: Animals; Benzimidazoles; Drug Evaluation; Drug Therapy, Combination; Mebendazole; Nematode Infection | 1979 |
The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole.
Topics: Abomasum; Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Female; Fen | 1977 |
Biological and pharmacological properties of flubendazole.
Topics: Animals; Benzimidazoles; Chickens; Dog Diseases; Dogs; Embryo, Mammalian; Embryo, Nonmammalian; Fema | 1978 |
The anthelmintic efficacy of mebendazole against adult Fasciola hepatica and a concurrent mixed nematode infection in sheep.
Topics: Animals; Benzimidazoles; Fasciola hepatica; Fascioliasis; Female; Mebendazole; Nematode Infections; | 1975 |
Anthelmintic activity of mebendazole against naturally acquired gastrointestinal nematodes in sheep.
Topics: Animals; Benzimidazoles; Female; Intestinal Diseases, Parasitic; Male; Mebendazole; Nematode Infecti | 1975 |
Effectiveness of strategic anthelmintic dosing in controlling Haemonchus contortus infections in sheep in the United Kingdom.
Topics: Animals; Anthelmintics; Drug Therapy, Combination; Feces; Female; Haemonchiasis; Levamisole; Mebenda | 1991 |
Clinical observations, diagnosis and control of H contortus infections in periparturient ewes.
Topics: Animals; Female; Haemonchiasis; Haemonchus; Hematocrit; Mebendazole; Parasite Egg Count; Pregnancy; | 1990 |