Page last updated: 2024-10-30

mebendazole and Necatoriasis

mebendazole has been researched along with Necatoriasis in 27 studies

Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.

Necatoriasis: Infection of humans or animals with hookworms of the genus NECATOR. The resulting anemia from this condition is less severe than that from ANCYLOSTOMIASIS.

Research Excerpts

ExcerptRelevanceReference
"This paper presents our experience with mebendazole, a new broad-spectrum anthelmintic, in 91 cases with ascariasis, 71 cases with necatoriasis 54 cases with trichuriasis and 10 cases with T."5.04Clinical trials with mebendazole a new broad spectrum anthelmintic. ( Dalal, NJ; Enjetti, E; Vakil, BJ, 1975)
"Mebendazole and pyrantel were equally effective in this system."1.27Response of preadult Necator americanus to some known anthelmintics in hamsters. ( Bose, S; Deb, BN; Dhage, KR; Rajasekariah, GR, 1986)
"Mebendazole-treated subjects remained worm-free and the hookworm egg counts of the controls decreased during the study period."1.26The relationship of hookworm infection, anaemia and iron status in a Papua New Guinea highland population and the response to treatment with iron and mebendazole. ( Blunden, RW; Casey, GJ; Kimber, RJ; Kutkaite, D; Payne, R; Shield, JM; Vaterlaws, AL, 1981)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's7 (25.93)18.2507
2000's1 (3.70)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wong, SJ1
Gunawardena, GS1
Karunaweera, ND1
Ismail, MM1
Shield, J2
Anian, G1
Ostwald, R1
Arnhold, R1
Shield, JM1
Vaterlaws, AL1
Kimber, RJ1
Payne, R1
Casey, GJ1
Blunden, RW1
Kutkaite, D1
Griffin, L1
Okello, GB1
Pamba, HO1
Kaul, CL1
Talwalker, PK1
Sen, HG1
Grewal, RS1
Bhopale, MK1
Menon, S1
Kamath, VR1
Sinniah, B2
Sinniah, D2
Dissanaike, AS1
Yang, WP1
Shen, YP1
Shao, JO1
Dong, K1
Zhong, T1
Hu, YL1
Xu, ZL1
Tang, CM1
Huang, JJ1
De Clercq, D1
Sacko, M1
Behnke, J1
Gilbert, F1
Dorny, P1
Vercruysse, J1
Nontasut, P3
Waikagul, J1
Muennoo, C1
Sanguankait, S1
Nuamtanong, S1
Maipanich, W2
Stoltzfus, RJ1
Albonico, M1
Chwaya, HM1
Tielsch, JM1
Schulze, KJ1
Savioli, L1
Kojima, S1
Georgiev, VS1
Botero, D1
Migasena, S1
Suntharasamai, P1
Harinasuta, T1
Breedveld, PH1
De Gues, A1
De Jong-Stoelinga, MH1
Vakil, BJ1
Dalal, NJ1
Enjetti, E1
Rajasekariah, GR2
Deb, BN2
Dhage, KR2
Bose, S2
Singhasivanon, V2
Prarinyanuparp, V1
Chiamratana, B1
Sanguankiat, S1
Dekumyoy, P1
Setasuban, P1
Holzer, BR1
Frey, FJ1
Yamput, S1
Visiassuk, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Drug Efficacy of Albendazole Bought on Local Market Against Soil-transmitted Helminth Infections in School Children in Jimma, Ethiopia[NCT02420574]679 participants (Actual)Interventional2014-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for mebendazole and Necatoriasis

ArticleYear
[Wakana disease].
    Ryoikibetsu shokogun shirizu, 1999, Issue:24 Pt 2

    Topics: Ancylostoma; Ancylostomiasis; Animals; Antinematodal Agents; Diagnosis, Differential; Humans; Intest

1999
Parasitic infections. Treatment and developmental therapeutics. 1. Necatoriasis.
    Current pharmaceutical design, 1999, Volume: 5, Issue:7

    Topics: Albendazole; Anemia, Iron-Deficiency; Animals; Drug Resistance; Humans; Mebendazole; Necatoriasis

1999
Chemotherapy of human intestinal parasitic diseases.
    Annual review of pharmacology and toxicology, 1978, Volume: 18

    Topics: Amebiasis; Amides; Ancylostomiasis; Ascariasis; Bephenium Compounds; Cestode Infections; Emetine; Fu

1978

Trials

6 trials available for mebendazole and Necatoriasis

ArticleYear
The anthelmintic effects of pyrantel pamoate, oxantel-pyrantel pamoate, levamisole and mebendazole in the treatment of intestinal nematodes.
    Annals of tropical medicine and parasitology, 1981, Volume: 75, Issue:3

    Topics: Anthelmintics; Ascariasis; Benzimidazoles; Child; Costs and Cost Analysis; Drug Administration Sched

1981
Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali.
    The American journal of tropical medicine and hygiene, 1997, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antinematodal Agents; Child; Child, Preschool; Double-Blind Method

1997
Minimum effective doses of mebendazole in treatment of soil-transmitted helminths.
    The Southeast Asian journal of tropical medicine and public health, 1997, Volume: 28, Issue:2

    Topics: Animals; Antinematodal Agents; Ascariasis; Ascaris lumbricoides; Child; Dosage Forms; Humans; Mebend

1997
Mebendazole, tetrachlorethylene and pyrantel pamoate in the treatment of hookworm infection.
    Annals of tropical medicine and parasitology, 1978, Volume: 72, Issue:2

    Topics: Adult; Benzimidazoles; Clinical Trials as Topic; Female; Hookworm Infections; Humans; Male; Mebendaz

1978
Clinical trials with mebendazole a new broad spectrum anthelmintic.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:7

    Topics: Adolescent; Adult; Ascariasis; Benzimidazoles; Cestode Infections; Child; Child, Preschool; Clinical

1975
Effect of single-dose albendazole and single-dose mebendazole on Necator americanus.
    The Southeast Asian journal of tropical medicine and public health, 1989, Volume: 20, Issue:2

    Topics: Adolescent; Albendazole; Animals; Child; Drug Therapy, Combination; Female; Humans; Male; Mebendazol

1989

Other Studies

18 other studies available for mebendazole and Necatoriasis

ArticleYear
A Rare But Curable Cause of Iron Deficiency Anemia.
    Gastroenterology, 2018, Volume: 154, Issue:4

    Topics: Aged, 80 and over; Anemia, Iron-Deficiency; Animals; Antinematodal Agents; Duodenal Diseases; Duoden

2018
Soil-transmitted helminthiases: number of children treated in 2013.
    Releve epidemiologique hebdomadaire, 2015, Mar-06, Volume: 90, Issue:10

    Topics: Adolescent; Albendazole; Ancylostoma; Ancylostomiasis; Animals; Anthelmintics; Ascariasis; Ascaris l

2015
Effects of climatic, socio-economic and behavioural factors on the transmission of hookworm (Necator americanus) on two low-country plantations in Sri Lanka.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Antinematodal Agents; Child; Child, Preschool; Climate; Feces; Fem

2005
Reinfection with intestinal helminths after treatment with mebendazole and fluctuations in individual Ascaris lumbricoides infections with time.
    Papua and New Guinea medical journal, 1984, Volume: 27, Issue:2

    Topics: Ascariasis; Benzimidazoles; Child; Drug Administration Schedule; Humans; Intestinal Diseases, Parasi

1984
The relationship of hookworm infection, anaemia and iron status in a Papua New Guinea highland population and the response to treatment with iron and mebendazole.
    Papua and New Guinea medical journal, 1981, Volume: 24, Issue:1

    Topics: Anemia, Hypochromic; Benzimidazoles; Drug Therapy, Combination; Ethnicity; Female; Ferritins; Folic

1981
Mebendazole: a preliminary study comparing its efficacy against hookworm with pyrantel pamoate (Combantrin) and bephenium hydroxynaphthoate (Alcopar) in patients at Kenyatta National Hospital.
    East African medical journal, 1982, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Aged; Benzimidazoles; Bephenium Compounds; Female; Humans; Kenya; Male; Mebendazo

1982
Changes in carbohydrate metabolism in golden hamsters infected with Necator americanus.
    Annals of tropical medicine and parasitology, 1982, Volume: 76, Issue:4

    Topics: Animals; Carbohydrate Metabolism; Cricetinae; Disease Models, Animal; Fatty Acids, Nonesterified; Gl

1982
The anthelmintic effects of mebendazole on Necator americanus in rabbit model.
    Journal of helminthology, 1982, Volume: 56, Issue:4

    Topics: Animals; Benzimidazoles; Eosinophils; Hemoglobins; Leukocyte Count; Mebendazole; Necatoriasis; Paras

1982
Single dose treatment of intestinal nematodes with oxantel-pyrantel pamoate plus mebendazole.
    Annals of tropical medicine and parasitology, 1980, Volume: 74, Issue:6

    Topics: Adolescent; Adult; Antinematodal Agents; Ascariasis; Benzimidazoles; Child; Child, Preschool; Drug A

1980
[Effect of combined chemotherapy against human intestinal nematode eggs].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1994, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Albendazole; Ancylostomiasis; Ascariasis; Child; Child, Preschool; Drug Combinati

1994
[Field studies on different control schemes for hookworm infection].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1993, Volume: 11, Issue:3

    Topics: Ancylostomiasis; Animals; Bephenium Compounds; Humans; Levamisole; Mebendazole; Necator americanus;

1993
Effects of the Zanzibar school-based deworming program on iron status of children.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:1

    Topics: Ancylostomiasis; Anemia, Iron-Deficiency; Animals; Antinematodal Agents; Ascariasis; Ascaris lumbric

1998
[Intestinal worm infestations in migrants from Surinam].
    Nederlands tijdschrift voor geneeskunde, 1977, Jul-09, Volume: 121, Issue:28

    Topics: Adult; Ascariasis; Child; Female; Helminthiasis; Humans; Intestinal Diseases, Parasitic; Levamisole;

1977
Response of adult Necator americanus to some known anthelminthics in hamsters.
    Annals of tropical medicine and parasitology, 1989, Volume: 83, Issue:3

    Topics: Animals; Cricetinae; Disease Models, Animal; Humans; Ivermectin; Mebendazole; Mesocricetus; Necator;

1989
Differential efficacy of mebendazole and albendazole against Necator americanus but not for Trichuris trichiura infestations.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:6

    Topics: Albendazole; Benzimidazoles; Humans; Male; Mebendazole; Necatoriasis; Trichuriasis

1987
Comparative study of different doses of mebendazole in hookworm infection.
    The Southeast Asian journal of tropical medicine and public health, 1987, Volume: 18, Issue:2

    Topics: Adolescent; Ancylostomiasis; Child; Child, Preschool; Drug Administration Schedule; Feces; Female; H

1987
A study of the effectiveness of mebendazole and pyrantel pamoate as a combination anthelmintic in Papua New Guinean children.
    Papua and New Guinea medical journal, 1985, Volume: 28, Issue:1

    Topics: Ascariasis; Benzimidazoles; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Mebendazole

1985
Response of preadult Necator americanus to some known anthelmintics in hamsters.
    Chemotherapy, 1986, Volume: 32, Issue:1

    Topics: Administration, Oral; Animals; Anthelmintics; Bephenium Compounds; Body Weight; Cricetinae; Dose-Res

1986